Aptamer Group

Aptamer Group focuses on the development of aptamer technology. We develop nucleic acid aptamers for research and development, biomarker discovery, diagnostics, or therapeutic development. Aptamers are short DNA or RNA sequences that provide high affinity and specificity for almost any type of target. As such, they can be considered synthetic nucleic acid equivalents to antibodies. Aptamers have a wide range of applications, are cost-effective, and can offer complementary or alternative solutions to antibodies. We have over 20 years of combined expertise in developing nucleic acid aptamers with peptides, proteins, cells, tissue samples, microorganisms, and small molecules.Aptamer Group has cutting-edge platforms suitable for aptamer selection. These include semi-automated selection platforms that ensure accurate replication of selection conditions to guarantee optimal aptamer results. We can work with a variety of targets: peptides, proteins, whole cells, viruses, small molecules, and more. The typical aptamer selection process can be completed within a few weeks. Monoclonal antibodies usually take months to generate.Our custom services can focus on specific applications so that the final aptamer is suitable for a given detection platform, sample type, and assay buffer.Aptamers themselves are increasingly being viewed as the best choice reagents for various applications, including:Imaging experiments: fluorescence, brightfield and phase contrast, IHC, ICCQuantification: ELISA (or ELONA), homogeneous assays, etc.Rapid diagnostics: lateral flow devices, biosensors, electrochemical detection, nanowiresBinding studies: label-free detection, SPR, Biolayer InterferometryPurification: affinity chromatographyWe also offer aptamer-based assay development services.Our solutions can identify aptamers suitable for almost any application under almost any condition for almost any target. Our applications are more diverse than those using antibodies. These include therapeutics, biomarker discovery, drug target discovery, diagnostics, biosensors as part of biochemical tests such as lateral flow devices, Enzyme-Linked Oligonucleotide Assay (ELONA: the aptamer-based equivalent of ELISA), affinity chromatography, and research reagents.For more information, please visit: www.aptamergroup.co.uk and www.aptamersolutions.co.uk