Jocasta

Jocasta Neuroscience is a preclinical-stage, longevity-focused company dedicated to developing a proprietary formulation of the a-Klotho protein (JN-0413) to manage cognitive decline associated with various forms of neurodegenerative-induced dementia. Jocasta's foundational data demonstrates the critical role of a-Klotho in both health and disease. From human genetics (the impact of KL mutations on humans) to robust cognitive enhancement in healthy rats, rodent disease models, and non-human primates, the results strongly support advancing JN-0413 into clinical trials for patients with dementia and cognitive decline.