Outrun Therapeutics

Outrun Therapeutics is unlocking the therapeutic potential of stabilizing proteins by inhibiting E3 ligases to maintain levels of key proteins that lose stability in certain diseases, thereby disrupting the body's highly complex natural disease-suppression processes. Compared to other approaches, blocking the activity of E3 ligases stabilizes proteins at the "source." It directly becomes part of the tagging mechanism used by healthy cells to destabilize dispensable or misfolded proteins. Protein stabilization can be applied across a wide range of indications, including oncology and neurology.