Deep Apple Therapeutics

Deep Apple Therapeutics discovers novel small molecule compounds for high-value targets at an unprecedented speed within the vast, untapped virtual chemical space. Deep Apple integrates cryo-electron microscopy of receptor conformation ensembles, deep learning, and docking of billions of compounds generated using the company’s proprietary Orchard.ai™ algorithm. Deep Apple's deep learning discovery engine is built on the founders' expertise in computational modeling, protein and target structure determination, large-scale molecular docking, and elucidation of protein dynamics and conformational changes. This structure-based, machine learning-driven drug design approach enables the company to rapidly develop novel drug candidates to address validated targets in inflammation, metabolic, and endocrine diseases.