Gate Neurosciences

Gate Neurosciences, headquartered in Indianapolis, is a precision medicine biotechnology company focused on advancing next-generation central nervous system (CNS) treatments to meet the growing mental health needs. Gate Neurosciences' mission is to address hallmark disease biology by developing safe, effective, and fast-acting therapies to meet the unmet needs of patients with CNS disorders. Our therapeutic candidates are specifically designed to target underlying synaptic dysfunction to restore healthy and balanced brain signaling. We are developing novel mechanisms that represent a more direct approach to enhancing synaptic function and neuroplasticity compared to other next-generation rapid-acting antidepressants.