Bonum

Bonum Therapeutics Focuses on Developing a New Class of Treatments Through Its Technology Platform. The platform leverages the principles of allosteric regulation to produce drugs with high potency and low toxicity. This technology will enable us to harness powerful central biologics in safe and effective medications. The company’s molecules combine a sensor component targeting specific biomarkers with a therapeutic component. When the sensor binds to its target, the molecule reversibly changes shape and becomes active, delivering potent activity only where needed. Bonum Therapeutics' technology is applicable across a wide range of therapeutic areas, including oncology, autoimmune disorders, metabolic diseases, and pain management. The company is initially focused on modulating immune cytokines, including conditionally active IFN-α, IL-12, and TGF-β, while collaborating with other companies to develop additional applications.