Totus Medicines

Totus Medicines, founded in 2019, uses revolutionary chemical biology to create life-changing therapies to treat previously incurable diseases across the entire human genome. Located in Cambridge, Massachusetts, Totus was established with the aim of bringing hope to the most vulnerable patients by making these diseases treatable. Totus Medicines' drug program, TOS-358, targets PI3Kα mutations, which affect more than 500,000 people annually in the United States and cause a significant proportion of breast cancer, colon cancer, lung cancer, bladder cancer, stomach cancer, and other cancers.