Calvert Laboratories

Calvert Laboratories is a preclinical CRO that offers a wide range of lead identification, lead optimization, and preclinical services, while providing clients with scientific guidance, excellent regulatory services, and customized research design services.Calvert Laboratories also provides lead identification and lead optimization services: offering pre-drug services in the fields of toxicology, pharmacology, immunology, pharmacokinetics/TK/ADME, and pharmacodynamics/toxicodynamics.In addition, Calvert Laboratories provides: 1. Bioanalytical evaluation services; 2. Screening services, including single-dose and multi-dose PK analysis, bioavailability/dose proportionality, mass balance, elimination/excretion; 3. Organ distribution studies, including ex vivo services, blood cell partitioning, and plasma protein binding studies; 4. In vitro ADME services, including drug metabolism enzyme inhibition and induction, reaction phenotyping, metabolic stability, metabolite profiling and identification, hepatotoxicity, and transporter studies.