Endoluminal Sciences

Endoluminal Sciences is a medical technology company that has developed a proprietary polymer-based platform technology to significantly enhance the clinical performance of endovascular prostheses. While the technology can be applied to a range of vascular disease treatments, the current focus is on structural heart disease and aortic aneurysm disease. Our unique approach combines mechanical engineering and polymer science to overcome critical failure modes of endovascular devices, particularly those related to paraprosthetic leakage, outperforming any devices currently in clinical trials or on the market. The company has developed a groundbreaking sealing technology that eliminates paraprosthetic leakage in endovascular devices, including paravalvular leakage in transcatheter heart valves, peridevice leakage in left atrial appendage implants, and endoleaks in endovascular stent grafts. This novel, highly expandable polymer-based technology actively seals devices within complex anatomical structures while enabling low-profile delivery. The technology is easily adaptable to current endovascular implants, preserving their durability and deliverability without requiring any learning curve for physicians. It is designed to overcome key anatomical limitations of most endovascular implants, thereby enhancing their clinical applicability and improving clinical outcomes.