Peptone

Peptone is a molecular computational biophysics company focused on protein drug discovery. Since its establishment in 2018, Peptone has combined atomic-level physical protein analysis technology to create accurate characterizations of intrinsically disordered proteins (IDPs) and protein regions, predicting the optimal approaches for drug targeting. The company conducts analyses by integrating nuclear magnetic resonance (NMR) spectroscopy, hydrogen-deuterium exchange mass spectrometry (HDX-MS), machine learning (ML), and supercomputing. Peptone’s technology has been tested through collaborations with leading pharmaceutical companies, assisting them in advancing previously "misbehaving" protein-based drugs through the pipeline to target partially disordered proteins.