DP Technology to Showcase AI for Science Innovations at J.P. Morgan Biotech Showcase 2025

RiDYMO® is a high-quality Hit discovery and optimization platform developed by DP Technology based on Al for Science. Relying on the independently developed Hermite® computational drug design software, it aims to unlock the kinetic mechanisms of difficult-to-drug targets through innovative artificial intelligence, physical algorithms, and high-throughput experiments, exploring a broader chemical space of small molecules, macrocyclic molecules, and cyclic peptide molecules. The platform has unique advantages in the design of orally available macrocyclic molecules, and when combined with parallel synthesis, it can rapidly deliver innovative drug candidate compounds. One of its core algorithms, Reinforced Dynamics (RiD), achieves nearly a hundredfold improvement in molecular simulation sampling efficiency. By fully leveraging the high-dimensional representation capabilities of neural networks, RiD can effectively capture dynamic conformational changes in complex biomolecular systems. RiDYMO® has been successfully applied to multiple projects, including the design of c-Myc small molecules, GPX4 small molecules, and β-catenin cyclic peptides, fully demonstrating its powerful potential in innovative drug discovery.

More information is available at: https://www.dp.tech/services/medicine

Hermite® is a next-generation drug computational design platform powered by Alfor Science and developed by DP Technology, providing a one-stop computational solution for preclinical drug research and development. It includes core modules such as the industry-leading free energy perturbation calculation tool Uni-FEP and the ultra-high throughput virtual screening tool Uni-VSW, empowering multiple stages including protein structure prediction, target validation, hit compound discovery, and lead optimization.

Hermite® provides an interactive, web-based molecular display experience with fine-grained management of projects, members, and data. It features comprehensive qualification certifications and multi-level security protection, supporting both online use and private deployment.

The Hermite® platform is highly trusted by customers, with over 60% of China's top industry users choosing to utilize the Hermite® platform. It has been applied in more than 50 drug pipeline projects, and customers have cumulatively conducted over 200,000 Hermite® Uni-FEP computing tasks.

More information is available at:https://www.dp.tech/product/hermite