Home Carvykti Q1 Sales Surge 135% to Over $2.65 Billion, Driven by Strong U.S. Demand and Expanded Indications

Carvykti Q1 Sales Surge 135% to Over $2.65 Billion, Driven by Strong U.S. Demand and Expanded Indications

Apr 16, 2025 14:45 CST Updated 14:45
Johnson & Johnson

Medical Device R&D and Manufacturer

On April 15, Johnson & Johnson disclosed in its Q1 2025 earnings report that Carvykti(Cilta-cel)Q1 Sales reached $369 million (approximately 2.65 billion yuan)Up 135% year-over-yearAmong which, the revenue from the U.S. market was 318 million U.S. dollars, increasing by 127% year-on-year.
Source: Johnson & Johnson Earnings Report
Carvykti is a B-cell maturation antigen-targeted therapy co-developed by Legend and Johnson & Johnson.(BCMA)Chimeric Antigen Receptor T-Cells(CAR-T)The therapy has currently been launched in multiple countries and regions, including China, the United States, the European Union, and Japan, and has been approved for the treatment of multiple myeloma. Among them,The United States and the European Union have expanded to second-line therapy in April 2024.
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Source:Insight Database
Carvykti isThe First and Only BCMA CAR-T Approved for Second-Line Treatment of Multiple Myeloma Patients, alsoThe First and Only Cell Therapy to Significantly Extend OS Compared to Standard Treatments in Multiple MyelomaSince its launch in 2022, sales have been steadily increasing. In 2024, with the introduction of frontline indications and increased market penetration, Carvykti's global revenue reached $963 million, making it the best-selling BCMA CAR-T product.
Source:Insight Database
To meet the strong global market demand for Carvykti, Legend and Johnson & Johnson have established four production bases in the U.S. and the EU, with a current turnaround time of 32 days. With sufficient supply and rapid global expansion of indications, market growth remains robust. Carvykti is expected to become the world’s best-selling CAR-T product in the future.

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