Home Sirius Therapeutics Secures Nearly $50M in Series B2 Financing; Haichuang Pharma's Deuterated Enzalutamide Approved for mCRPC

Sirius Therapeutics Secures Nearly $50M in Series B2 Financing; Haichuang Pharma's Deuterated Enzalutamide Approved for mCRPC

Jun 11, 2025 09:31 CST Updated 09:31
Sirius Therapeutics

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Financing Information

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Sirius Therapeutics | Announces Completion of Nearly 50 Million USD Financing to Accelerate Clinical Development of siRNA Therapies for Cardiovascular Metabolic Diseases

On May 9, 2025, Sirius Therapeutics announced the successful completion of a nearly US$50 million Series B2 financing round to accelerate the clinical development of its novel small interfering RNA (siRNA) therapies for cardiometabolic diseases and to further innovate its next-generation RNA delivery technology. This round of financing was led by a globally renowned industry investment institution, with participation from BioTrack Capital and existing investors Orbimed, Hongyuan Capital, and Hanscan Capital.


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Acchrom Tech | Announces Completion of Over 100 Million Yuan Pre-B Round Financing

Full Range of Chromatography Equipment, Software, and Consumables Made in ChinaPlatform EnterpriseAcchrom Tech (Beijing) Co., Ltd.("Acchrom Tech" hereinafter)Completed Pre-B Round Financing of Over 100 Million YuanThis round of financing was co-led by Jingguorui Fund and Beijing High-Precision Fund managed by BGIC, with follow-up investments from existing shareholders Hony Capital and Bridge Capital., The funds raised in this round will be mainly used for further construction of sales channels at home and abroad and the development of the next generation of products.


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Salus|Announces Completion of A+ Round Financing, Accelerating Global Expansion

Salus Medical Technology (Shenzhen) Co., Ltd. (hereinafter referred to as "Salus") announced the completion of its Series A+ financing. This round of financing was led by Fosun Pharma, a leading company in the healthcare industry, with Changzhou Weichi Investment participating, and existing shareholder Shenzhen Capital Group continuing to increase its investment.This round of funding will focus on the registration and application of China's national sequencing platform, capacity expansion, and the globalization of market expansion, further consolidating its leading position in innovation within the life science tools sector.


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Business Progress

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CANbridge|Announces the Approval and Launch in China of Velaglucerase Alfa for Injection (Brand Name: Gornin), a Novel Drug for the Treatment of Type I and Type III Gaucher Disease

On May 16, 2025, CANbridge Pharmaceutical Inc. (hereinafter referred to as "CANbridge", stock code "01228.HK") announced that its wholly-owned subsidiary, CANbridge (Shanghai) Biotechnology Co., Ltd., obtained approval from the National Medical Products Administration for the listing of Velaglucerase Alfa for Injection (brand name: Gorenin).Gorining is the first domestically self-developed enzyme replacement therapy in China for long-term treatment of Type I and Type III Gaucher disease in patients aged 12 years and above, including both adolescents and adults. As an innovative Class 1 drug, it can fully replace similar imported products, significantly improving the accessibility of treatment for patients in China.

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HaiChuang Pharma | New Prostate Cancer Drug "Deuterated Enzalutamide" Approved for Marketing

On May 29, it was learned from the NMPA website that Hycure Pharma (688302.SH) independently developed Class I new drug Haina An® (generic name: Deuterated Enzalutamide Soft Capsules), which has been approved for marketing by the National Medical Products Administration., for the treatment of adult patients with metastatic castration-resistant prostate cancer (mCRPC) who have experienced disease progression after receiving abiraterone acetate and chemotherapy, and who have not previously received novel androgen receptor inhibitors.As a project supported by the National Science and Technology Major Project for Significant New Drug Development, deuterated enzalutamide soft capsules are the first domestically produced innovative drug approved for marketing in China to treat this indication.


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Genor Biopharma | First-in-class Innovative Drug Rujiane® (Lerociclib Hydrochloride Tablets) Approved for Marketing

On May 29, Genor Biopharma (Cayman) Holdings Limited ("Genor Biopharma") announced that the National Medical Products Administration (NMPA) of China had approved the New Drug Application (NDA) for Lerociclib tablets (GB491). Lerociclib is indicated for adult patients with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative (HR+/HER2-) locally advanced or metastatic breast cancer.

  • In combination with aromatase inhibitors as initial endocrine therapy

  • In combination with fulvestrant for patients with disease progression after prior endocrine therapy

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Zhongsheng Pharmaceutical|China's Original Innovative Drug Aoladiwei Tablets Approved for Marketing, World's First RNA Polymerase PB2 Target Leading New Breakthrough in Influenza Treatment

May 22,China's National Medical Products Administration (NMPA) has officially approved the marketing of Oradawir Tablets (trade name: Anruiwei®), a Class 1 innovative drug developed by Guangdong Zhongsheng Ruichuang Biotechnology Co., Ltd., for the treatment of adult patients with uncomplicated influenza A.

As the world's first anti-influenza drug targeting the PB2 subunit of the RNA polymerase of the influenza A virus, Aorladivir provides a brand-new "Chinese solution" for global influenza prevention and control with its rapid, potent, and low-resistance characteristics.

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Sirius Therapeutics | Next-Generation Long-Acting FXI-Targeted siRNA Licensed Overseas

On May 20, Sirius Therapeutics and CRISPR Therapeutics announced a strategic partnership to jointly advance the co-development and commercialization of siRNA therapies. This collaboration combines the complementary capabilities of both parties in research and development as well as industrialization, aiming to co-develop and commercialize SRSD107, a next-generation long-acting Factor XI (FXI) targeted small interfering RNA (siRNA) therapy, for the treatment of thrombotic and thromboembolic diseases.

According to the terms of the agreement, Sirius Therapeutics will receive $95 million in cash and cash equivalents as an upfront payment from CRISPR Therapeutics and is eligible to receive over $800 million in upfront and milestone payments. The two parties will jointly develop SRSD107 under a 50:50 cost and profit-sharing mechanism. Additionally, the agreement grants CRISPR Therapeutics the exclusive right of first negotiation to license up to two additional siRNA programs in the future.


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Enterprise Honors

Beiqi Biotech | Professor Deng Hongkui Selected by TIME MagazineTIME100 Health: The Most Influential People in Global Health 2025





NewMed|Prizvalve Main Valve System Honored2025 Global Cardiovascular Technology Innovation Award




Qianglian, Haijeya, Meili Weiye, Maixin Health, Boya Gene, Ruifeng Bio|

Awarded "Top 50 Most Influential Companies in Healthcare Investment and Financing in China's Healthcare Industry in 2024"





Shenluo Medical, Cargene Biotech|Awarded "2024 China Healthcare Industry Investment & Financing Honor Roll: Top 50 Most Investment-Worthy Companies in Healthcare"


SurgSharp Medical, D-Join Medical, Telight Medical, EaseSurge Medical, Qitan Tech, NewMed Medical, HAIJIEYA, Concorde Medical, Calibre, Eukomed Medical, StrongLink Intelligence, FarHill Medical, Banger Technology|

"Artery Network · 2025 Future Healthcare 100 Strong: Top 100 List of China's Innovative Medical Devices and Intelligent Manufacturing"





Shanghai Haihe, Aikang Bio, Zhencon Raytron, Changfeng Pharmaceuticals, Hangzhou Jiayin Bio, Yanming Bio, Boya Gene Editing, Liminus Pharma, Hengmei Health, Beiheng Bio, Ruifeng Bio |

"Artery Network · 2025 Future Healthcare 100 Strong: Top 100 in China's Innovative Pharmaceuticals and Biologics"





Magnacare, Anzgene Biotech, Yunhu Tech, Yibao Tech|

"Arterial Network · 2025 Future Healthcare 100 Strong: Top 100 China Healthcare and Innovation Service List"





Acchrom Tech, MedIntelligent, CareGroup, Huimei Digital Technology, Acchrom Tech

"Artery Network · 2025 Future Healthcare 100 Strong China Healthcare Industry Chain Service List TOP100"





HuiMei Data Technology | "2025 Future Healthcare 100 Strong Annual Innovation Enterprise"





Yizhi Technology | "2025 Future Healthcare 100 Strong - Annual Rising Enterprise"






Aikang Biopharma, Canbridge Pharma, Changfeng Pharmaceuticals, Ray Therapeutics|

"Artery Network · 2025 Future Healthcare 100 Strongest Best Biotechnology Innovation Product"





Huihe Medical | "Arterial Network · 2025 Future Healthcare 100 Strong Valuable Products/Solutions"






Boyu Honor

Artery Network | Boyuan Capital Honored with "2025 Future Healthcare 100 Strong - Annual Healthcare Leader Investment Institution", "2025 Future Healthcare 100 Strong - Annual Healthcare Innovation Track Investment Institution" & Boyuan Capital Founding Partner Chen Penghui Honored with "2025 Future Healthcare 100 Strong - Annual Healthcare Leader Investor"


First New Voice | Boyuan Capital Honors "Invest in China - Top 10 Most Active Healthcare Investment Institutions Q1 2025"




CHC Medical Consulting, CITIC Securities | Boyuan Capital Founding Partner Chen Penghui Awarded "Top 50 Most Influential Investors of the Year 2023"





Disclaimer: The information in this report is sourced from publicly available materials. Our company does not guarantee the accuracy or completeness of this information. The copyright of the report belongs solely to our company, and no institution or individual may reprint, reproduce, publish, post, or quote it in any form without written permission.


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