Home Global Pharma Top 50 Rankings Unveiled: Johnson & Johnson Retains Lead, Chinese Pharma Companies Shine

Global Pharma Top 50 Rankings Unveiled: Johnson & Johnson Retains Lead, Chinese Pharma Companies Shine

Jun 22, 2025 10:45 CST Updated 10:45
Johnson & Johnson

Medical Device R&D and Manufacturer

Sino Biopharm

Pharmaceutical R&D Developer



Main Body: 2008Word4Figure

Estimated reading time: 5Minute



Image Source:Pharmaceutical Executive (hereinafter the same)

On June 20, 2025, the globally renowned industry media Pharmaceutical Executive announced its annualTop 50 Global Pharmaceutical Companies2025 Pharm Exec Top 50 Companies, the listRanking the top 50 pharmaceutical enterprises globally based on prescription drug sales has a significant impact on the industry.

Johnson & Johnson topped the list again with sales of $55.745 billion. It was followed by AbbVie and Merck, ranking second and third with sales of $54.484 billion and $54.314 billion respectively. These companies not only excelled in sales but also demonstrated strong capabilities in R&D investment. Merck, Johnson & Johnson, and Roche invested $17.865 billion, $17.034 billion, and $14.818 billion respectively in R&D.


TOP 10


Johnson & Johnson, AbbVie, Merck & Co., Roche, Pfizer, AstraZeneca, Novartis, Bristol-Myers Squibb, Sanofi, Novo Nordisk





TOP 11 ~ TOP 30


Lilly, GSK, Amgen, Takeda, Gilead, Boehringer Ingelheim, Bayer, CSL Behring, Viatris, Teva, Astellas, Vertex, Daiichi Sankyo, Sandoz, Merck Group, Otsuka, Regeneron, Biogen, Grifols, Organon






TOP 31-50


Sun Pharma, UCB,Yunnan Baiyao, Servier, Abbott, Bausch + Lomb, Fresenius, Eisai,Sino Biopharm、Menarini、East China Pharmaceutical, Stada, Jazz Pharmaceuticals, BeiGene, Ipsen,Hengrui Medicine, Incyte,CSPC Pharmaceutical Group, Dr. Reddy's Laboratories, Moderna




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Notably, Chinese pharmaceutical companies also performed impressively in this ranking, with several entering the global top 50 pharmaceutical companies list. Yunnan Baiyao ranked 33rd, unchanged from last year. Sino Biopharm ranked 39th, dropping one position compared to last year. Huadong Medicine ranked 41st, appearing on the list for the first time. Hengrui Medicine ranked 46th, rising two positions from last year. CSPC Pharmaceutical Group ranked 48th, returning to the list.


The listing of these Chinese pharmaceutical companies not only reflects the rapid development of China's pharmaceutical industry but also demonstrates global market recognition of Chinese pharmaceutical enterprises.


A Quick Review of the Listing Status of Chinese Pharmaceutical Companies in the Past Five Years.


In the 2024 Pharm Exec Top 50 ranking of global pharmaceutical enterprises, four Chinese pharmaceutical companies were listed. These four Chinese pharmaceutical companies are: Yunnan Baiyao (ranked 33rd), Sino Biopharm (ranked 38th), Shanghai Pharmaceutical Group (ranked 42nd), and Hengrui Medicine (ranked 48th). Among them, Sino Biopharm has been listed for six consecutive years, Yunnan Baiyao returned to the list, while CSPC fell out of the TOP50.


In the 2023 Top 50 list, four Chinese pharmaceutical companies were ranked: Sino Biopharm (ranked 39th), Shanghai Pharmaceutical Group (ranked 41st), Hengrui Medicine (ranked 43rd), and CSPC Pharmaceutical Group (ranked 48th).


In 2022,Four Chinese pharmaceutical companies made the list: Hengrui Medicine (ranked 32nd), Sino Biopharm (ranked 40th), Shanghai Pharmaceuticals (ranked 41st), and CSPC Pharmaceutical Group (ranked 43rd). This achievement demonstrates that the competitiveness and influence of Chinese pharmaceutical companies in the global pharmaceutical industry are gradually increasing.


In 2021,A total of five Chinese pharmaceutical companies made the list, the most in history. They are: Yunnan Baiyao, Hengrui Medicine, Sino Biopharmaceutical, Shanghai Pharmaceuticals, and CSPC. Among them, Yunnan Baiyao ranked 34th, Hengrui Medicine ranked 38th, Sino Biopharmaceutical ranked 40th, Shanghai Pharmaceuticals ranked 42nd, and CSPC ranked 44th.


Believe that from now on, more Chinese pharmaceutical companies will make it to the list.


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Overall, this list not only showcases the market positions of global pharmaceutical companies but also reflects their efforts in R&D innovation and market competitiveness. As global demand for health and medical services continues to grow, these pharmaceutical giants will continue to play a significant role in innovative drug development and market expansion. Meanwhile, the rise of Chinese pharmaceutical companies is injecting new vitality and reshaping the competitive landscape of the global pharmaceutical industry.


References:

1. 2025 Pharm Exec Top 50 Companies

2. Top 50 Pharmaceutical Companies Worldwide in 2023 Revealed! (With List)

3. R&D Investment Triples! Changes in the TOP50 List of R&D Investment by Chinese Listed Pharmaceutical Companies from 2018-2021: PD-1 Has Become a Core Competitiveness

4. Before 2030, 24 of the TOP50 blockbuster drugs will face a patent cliff, with a total value of up to USD 166.45 billion.

5. Top 50 Global Pharmaceutical Companies in 2022 and Their Best-Selling Drugs

6. Top 50 Global Pharmaceutical Companies in 2021 and Their Best-Selling Drugs

7. PharmTimes Has Published Articles

8. Other Public Information

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Image Source: Pharmaceutical Executive

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