C-MIC: Sustained Improvement in Heart Failure Symptoms and LVEF Even After Discontinuation of Microcurrent Therapy

Jul 22, 2025 22:15 CST Updated 22:15

Berlin Heals

Developer of Cardiac Disease Treatment Devices

Berlin HealsAnnouncement in the journal "SC Heart Failure journal》Release onMicrocurrent Technology---C-MIC Two-year clinical data of FIM.Research shows:Research results showing clinical benefits maintained even after active treatment termination.

Specific Research Data

No device-related adverse events reported within two years.
C-MICAfter discontinuation, the improvement in left ventricular ejection fraction increased from 11.6% at 6 months to 12.6.%
6-Minute Walk Distance Increased by Over 200 Meters at 6 Months, Remaining 191 Meters Above Baseline After Two Years
New York Heart Association Functional Classification and SF-36 Quality of Life Score Continuously Improve
Among 7 patients, only 1 patient required a restartC-MICTreatment

PI Evaluation

"These findings provide important clinical evidence for the long-term potential of C-MIC therapy. Most excitingly, cardiac function and patient quality of life continued to improve even after device discontinuation, indicating the therapy's ability to alter disease progression."

---Dragana Kosevic Co-Chief Investigator

Executive Evaluation

"The publication of this study strengthens our confidence in the transformative potential of microcurrent therapy for heart failure treatment. The two-year results validate the safety and sustained efficacy of C-MIC, laying the groundwork for larger-scale clinical trials."

---John Brumfield CEO of Berlin Heals

C-MIC

C-MICIt is a new type of implantable electronic device (which looks somewhat like a pacemaker). It delivers a constant direct current equivalent to physiological intensity to the heart through two leads, one located on the epicardium of the left ventricle and the other in the cavity of the right ventricle.C-MICIt is through this microcurrent therapy that reverse remodeling of myocardial tissue is achieved.。

The patient is in a constantWith the help of microcurrent, the inflammatory parameters of the patient's cardiac tissue continue to improve, and edema (excess water) is drained from the heart.

C-MIC Advantages

Even ifPause, Still Able to Continuously Improve
Implantation is a minimally invasive surgery that takes less than an hour.
Almost no necessity for subsequent intervention
No external power supply required
NYHA class decreased by 2 levels in June
Reduce the number of hospitalizations per year
Reduce the Cost of Heart Failure Treatment
Clinical signs of comprehensive improvement can appear within 4 weeks.

C-MIC Demonstration

Berlin Heals

Berlin HealsIs a Swiss innovative medical device company founded in 2015.Berlin HealsIs leading people into a new era of treating heart failure. Heart failure is the leading cause of death worldwide, and it employs microcurrent as a treatment method.Berlin HealsA Preliminary Study on an Innovative and Disruptive Implantable, Minimally Invasive Microcurrent Device Clearly Demonstrates Unprecedented Significant Clinical Outcomes, with Marked Improvement in Ventricular Function and Cardiopulmonary Exercise Capacity, and Favorable Safety.