JensCare's Self-Developed Preloaded Dry Valve Prostyle A® Completes First Clinical Implantations Following NMPA Approval

Recently,"Kingstron Bio"Prostyle, a self-developed pre-loaded dry valve productA®Under the leadership of Professor Mao Chen's team from the West China Clinical Medical College of Sichuan University, Professor Guangyuan Song's team from Anzhen Hospital affiliated with Capital Medical University, and Professor Wensheng Chen's team from Xi'an High-tech Hospital,Successfully completed clinical implantation。

This is ProstyleA®In April this yearThe First Batch of Clinical Applications Completed After Obtaining NMPA Approval for Marketing, RelatedSuccess of the Surgery, which not only demonstrates Kingstron Bio's commitment to bringing cutting-edge research results to truly serve patients, but also signifiesChinaTAVR Treatment Officially Enters the Dry Valve Era。

Sticking to the Source of Innovation, Leading the Medical Journey: Anchoring clinical pain points and continuously深耕, is the innovation code engraved in the genes of Huaxi. Since the establishment of Huaxi Hospital, generations of medical professionals have taken攻克医学难题 as their responsibility. This spirit has been passed down, driving us to explore unknown fields. Our team and the Kingstron Bio team jointly developed the world's first pre-installed dry valve Prostyle.A®The Transcatheter Artificial Aortic Valve Replacement System represents a revolutionary concept in valve products. From the "standardization and convenience" of product design to the industry's focus on "durability," it addresses the practical pain points in the development of the valve industry. Innovation begins with clinical needs and will ultimately return to clinical practice. We look forward to innovative pre-loaded dry valves providing more solutions for clinical use.

Refining Technical Breakthroughs, Deepening Clinical Applications: With the continuous advancement of clinical TAVR applications, industry pain points have gradually emerged. Traditional TAVR wet valves, which rely on glutaraldehyde solution for preservation, inevitably encounter issues of aldehyde residue, affecting the biocompatibility of the valve and accelerating the calcification process. However, Prostyle...A®Preloaded dry valve, the brand-new dry storage is backed by an anti-calcification technology platform, providing a more durable guarantee for the valve. The preloaded structure moves the valve assembly process forward and standardizes it, eliminating the possibility of loading errors compared to traditional wet valves, and can be prepared for loading in just 5 minutes. Technological innovation propels the long-term development of the TAVR field, looking forward to Prostyle.A®To provide new technical pathways for optimizing clinical treatment plans and improving patient outcomes.

Refining Innovative Dry Valves, Strictly Upholding Data Integrity: Pre-installed dry valves represent a breakthrough innovation, breaking free from the limitations of traditional wet valves and offering patients a new choice. As medical practitioners, we must have the courage to embrace technological advancements while adhering to the principle of rigorous precision, ensuring every surgery stands the test of time — "Technological innovation must be measured by clinical standards and proven by data." Every preoperative evaluation, every postoperative assessment, every patient's long-term follow-up, and data analysis are crucial to verifying clinical efficacy. By allowing innovation to take root in clinical practice, we jointly safeguard the health of patients' 'heart valves.'

Technological innovation never stops, and the pursuit of creativity never ceases.: Everything starts from the patient, and the relentless pursuit of innovation is a steadfast belief. The exploration of 'ALL IN ONE' back in the day was driven by this original intention — by integrating instruments and procedures, we minimize access trauma, allowing patients to recover more quickly through minimally invasive techniques. This is technology's gentle promise to patients. Intraoperative brain protection is another line of defense we have established for safety.

The clinical application of this pre-mounted dry valve allows us to confront the clinical dilemma of valve "durability," and we look forward to innovative technologies supporting lifecycle management!

The Path of a Doctor: Shouldering Dual Responsibilities in Clinical Work and Management

In addition to leading the team to continuously improve their clinical skills, we in the clinic are also looking forward to technological innovations—more handy instruments that can solve practical problems in clinical practice.Preloaded Dry Valve ProstyleA®The advent of undoubtedly brings new hope to the clinical field.Micro-EX™ Patented Anti-calcification Technology: Utilizing nanotechnology to remove cellular debris and phospholipids from tissues, and blocking free aldehyde groups, this technology fundamentally interrupts multiple factors contributing to valve calcification, significantly enhancing the durability of the valve. At the same time, it maximally preserves the hydrophilic-lipophilic balance of the pericardium, restoring the tissue's natural flexibility. The emergence of this technology represents a significant breakthrough in the medical field and brings new hope for the long-term management of valve health in clinical patients.

Prostyle A®It is the world's first pre-loaded dry valve product independently developed and launched by Kingstron Bio., and in April this yearSuccessfully obtained approval for marketing from the National Medical Products Administration (NMPA)(NMPA Registration No. 20253130729).

This product integrates numerous cutting-edge technologies in the field of valves, featuring dry valve technology, a clever and convenient pre-loading system, excellent hemodynamic performance and durability of the valve, superior deliverability and passability, smooth deployment, and reliable anchoring.

Prostyle A®Safety and Efficacy of Treating Aortic StenosisAlso previously carried out by top hospitals in China and many renowned cardiovascular experts, including West China Hospital of Sichuan University, the Second Affiliated Hospital of Zhejiang University School of Medicine, the First Affiliated Hospital of Air Force Medical University of the Chinese People's Liberation Army, the Second Xiangya Hospital of Central South University, Beijing Anzhen Hospital Affiliated to Capital Medical University, Shanghai Chest Hospital, Cardiovascular Hospital Affiliated to Xiamen University, Nanjing First Hospital, Peking University Third Hospital, Union Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology, and Yunnan Fuwai Cardiovascular Hospital.Test Confirmed。

Prostyle A®It is Kingstron Bio's pioneering exploration of cutting-edge technology and a representative product of Kingstron's innovative solutions to clinical challenges. Next, accompanied by Prostyle...A®With the successive clinical implantations, its excellent clinical performance will continue to be validated. We look forward to Kingstron Bio's independently innovated dry valve technology and its products, under the guidance of relevant hospitals and experts, bringing "more durable" new hope for heart health to more patients.

Source: Kingstron Bio