Lingchuang Yigu Raises Nearly RMB 200 Million in Series B Funding to Advance Wireless Energy Transfer-Based Brain-Computer Interface and Neuromodulation Platforms

Leadinno Medical Valley News Recently，Leadinno Medical Valley (hereinafter referred to as"Leadinno Medical Valley" announced the completion of a nearly 200 million RMB B-round financing. This round of financing was jointly led by Shunxi Fund and Yizhuang Guotou, with participation from Galaxy Innovation Capital, Guangzhou Industrial Investment Capital, and Yizhuang Investment. Yuan Yi Capital serves as the company's long-term strategic advisor.

The financing is mainly used for establishing new production bases in Yizhuang, Beijing, and Keqiao, Shaoxing, to meet the needs of registration clinical trials and future commercialization. It will also support the rapid expansion from the existing wireless-powered spinal cord stimulation (SCS) product to other pipelines, including peripheral nerve stimulation (PNS), sacral nerve stimulation (SNS), and deep brain stimulation (DBS).Extended R&D.

It is reported that Leadinno Medical Valley was founded2016Founded in , Leadinno Medical Valley mainly develops two major technology platforms: wireless energy transmission and in-body chips, for neuromodulation and future brain-computer interface technologies.Extension.NucleusHeart TeamLed by Academician Han Jisheng, the founder of China's pain research field, and Professor Fan Bifa, the academic leader of China's pain science, as chief scientists, the team has long been committed to innovation in pain management and neurostimulation technology. The related technologies fall under neuromodulation./One of the representatives of domestically produced brain-computer interface in China. In the field of neuromodulation, it owns a full-stack platform capable of system integration loop closure from power supply to chips.。

In terms of product development,Currently, breakthroughs have been achieved in the self-developed key modules; in terms of technical architecture, Leadinno Medical Valley adopts a fully self-developed"Wireless Power Supply + Smart Chip + Multi-mode Stimulation" System Solves Pain Points of Traditional IPG Products Such as Complex Intraoperative Wiring, Large Size, and Difficult Postoperative Maintenance. Its Wireless Power Transmission Technology Can Efficiently Transfer Energy Without Interrupting the Skin, Significantly Improving Patients' Quality of Life and Device Durability.

Leadinno Medical Valley's first wireless-powered spinal cord stimulation (SCS) products initiated registration clinical trials earlier this year. The project is advancing simultaneously in 15 hospitals across China, with a planned enrollment of 70 cases, and more than half have already been enrolled.In terms of clinical outcomes, the analgesic effect was significant, with patients' pain scores decreasing from severe to mild, and their sleep and mood showing marked improvement.

On the basis of comparable analgesic effects, the system can reduce the operation time from traditional methods.Reduced from more than 2 hours to about 30-40 minutes, and no need for wound expansion to locate the IPG implantation site during the procedure, greatly simplifying the doctor's operation process and reducing the burden on patients.

In addition, the independently developed peripheral nerve electrical stimulation (PNS) products also adopt wireless power transmission technology. PNS products use a new wireless power transmission solution, with smaller implanted electrodes in the body and a more lightweight external stimulator, better meeting patients' needs for daily and long-term wear.

And the population of Leadinno Medical ValleySCS and PNS products can form a good synergistic effect. SCS products mainly target moderate to severe chronic pain in the trunk area, while PNS products are suitable for mild to moderate pain in the head, face, and limbs. The two complement each other, providing comprehensive solutions for patients with chronic intractable pain, ensuring that patients at different stages of the disease, with varying degrees of pain, and in different pain locations can receive appropriate treatment.

All products implanted with sensing chipsAll integratedThe core stimulation unit is completely self-designed.ASIC chip driver, with a package size controlled to less than 1×3 millimeters, features low power consumption, low latency, and high drive capability. It supports various stimulation modes such as high frequency, low frequency, burst, and random, and can adapt to different neuromodulation requirements.

Currently Leadinno Medical Valley mainlyLed by China-Japan Friendship HospitalMore than 20 clinical centers have established cooperation, and joint research with Peking University, the Chinese Academy of Sciences, and other research institutions has deepened fundamental studies in neuromodulation, providing a comprehensive solution in the field of neuromodulation.

In the field of brain-computer interfaces, Leadinno Medical Valley is also collaborating with related enterprises to expand frontier directions such as promoting awakening in patients with disorders of consciousness, lower limb motor rehabilitation after spinal cord injury, and post-stroke rehabilitation. Relying on the dual-platform barriers of wireless energy transmission and self-developed chips, it can cover a product matrix for different indications and different patient levels.

The current trend of global population aging is inevitable, and in the future, China alone will see an increase of over2Hundreds of millions of peopleCrossEnter intoPeople aged 60 and above. Due to the degeneration of cardiovascular and bone tissues in the elderly population, there is a significant clinical demand for pain management and emotional management. The industry predicts that within the next five to ten years, the market potential for pain management alone could reach tens of billions of US dollars.

And with the futureAI Artificial Intelligence andBrain-Computer Interface TechnologyBreakthrough: Tissue repair implant technology is becoming increasingly mature. Pain management, together with brain-computer collaboration, can not only serve patients and the elderly population but will also see more application scenarios in the field of productivity.

Leadinno Medical Valley"Wireless Power Transmission" and "In-body Stimulation Chip" Two Major Technology PlatformsRepresents the mainstream development direction of the industry's future, so itsExcellent product definition, engineering, and commercialization capabilities have also been widely recognized by the capital market.Leadinno Medical Valley also stated,The field of neuromodulation has become the most active product track both in China and internationally, with various innovative clinical applications emerging continuously.Leadinno Medical ValleyWill continue to adhere to the technical route that combines independent innovation with clinical needs, and looks forward to becoming a representative Chinese neuromodulation company., and forThe Development of Brain ScienceOwn Contribution。

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