Popular Hemorrhoid Drug Titanoreine Suppositories Withdrawn from China Market, Prices Surge Nearly 40-Fold Following Discontinuation

Internet-famous hemorrhoid medicine Compound Carrageenate Suppositories (trade name“Tainingshu”) Completely withdraw from the Chinese market.

10Month15On [date], the National Medical Products Administration announced the deregistration of loratadine tablets, etc.80Announcement of a drug registration certificate. This includes Titanoreine, with its two dosage forms.——The approval numbers for creams and suppositories have been canceled upon application. Apart from Taian, the drugs with canceled approval numbers this time also include several medicines from foreign enterprises, such as Pfizer's Doxorubicin Hydrochloride for Injection and Xian Janssen's Compound Carraghenates Suppository./Darunavir and Cobicistat Tablets/Fentanyl Transdermal Patch, GlaxoSmithKline's Salbutamol Sulfate Inhalation Solution, Sanofi's Lixisenatide Injection, Bayer's Rivaroxaban for Dry Suspension/Injectable Hydrochloric Acid Copanlisib, etc.

According to the application cancellation list published by the National Medical Products Administration, the cancellation of this approval number is an active action by the company.

Among them, the well-known hemorrhoid medicine Tai Ning Suppository has been...2023Year11It was discontinued in the month. Public information shows that Tai Ning is an exclusive product of Xian Janssen, a topical over-the-counter medication used for symptomatic treatment of pain, itching, swelling, and bleeding caused by hemorrhoids and other anal disorders. It can also be used to relieve discomfort following anal surgery.

Before the product was reported to be out of supply,3.4g×6The specification of Tai Ning Suppository is only20～40Yuan,3.4g×12The price per unit is40Yuan-80Yuan. According to the Health Client of "People's Daily"2024Year7Monthly Report: After the Supply Cut, the Price of Taining Suppositories Rose20Multiple times, at that time, only a few pharmacies on major e-commerce platforms were supplying Tai Ning Suppositories, among which3.4g×6The selling price of each specification is generally at500-600Yuan,3.4g×12The price per unit is1100-1200Yuan.

10Month22Recently, the Interface News queried various e-commerce platforms and found that currently6Price per unit856Yuan Zhi966Varies. On JD.comAPP, with3.4g×12Piece/The price of the box is as high as1858Yuan,3.4g×6Piece/Box of3Priced as high as (per box)2684Yuan, the merchant also clearly marked the expiration date as2026Year4Month.

According to the Red Star Capital Bureau, the reporter called the customer service number of Xian Janssen, and the staff stated that the company had already2023Stopped in the yearTainingPlugThe production and market supply of this drug, which has a validity period of36months. Currently, drugs on the market within their validity period can be sold normally, and the retail price is determined by retailers based on market strategy, operating costs, market competition environment, and actual business conditions.

It is reported that the main active ingredient of Compound Carrageenate is naturally extracted and non-renewable, and currently, there is no raw material available for sustainable production globally. Because of this, Xian Janssen Pharmaceutical Ltd.2023Year10Month19Submitted a withdrawal application to the National Medical Products Administration.

Public information shows,TaininePlugIn2001Introduced to the Chinese market by Xian Janssen in the year, it once ranked among the top five in China's hemorrhoid sales market after its launch, but later due to domestically produced...Ma Ying LongThe launch of hemorrhoid cream and other products has been defeated by the competition.