AccuPulse PFA System Achieves Successful Clinical Application at Shanghai Sixth People's Hospital as Part of National Pilot Program

Recently,Shanghai Sixth People's HospitalAs one of the first clinical application units in China, byDirector Shen Chengxing's Cardiology Team Led by Professor Wang Yuanlong and His TeamApplication of AccuPulse by AccuPulse Medical^®Single-use Cardiac Pulsed Field Ablation Catheter and AccuBlator^®AccuPulse Medical Technology Co.Ltd's cardiac pulsed field ablation system successfully performed a cardiac pulsed field ablation (PFA) procedure on a patient with atrial fibrillation.

The patient in this surgery is a 65-year-old male with persistent atrial fibrillation. The success of the surgery began with the precise and safe establishment of the entry point. AccuQuest was selected for this procedure.^®The atrial septal puncture needle performed exceptionally well, with precise and stable puncturing, laying a solid foundation for the smooth progress of subsequent operations.

Preoperative Left Atrial Modeling Diagram

Schematic Diagram of Substrate Mapping After Ablation

Professor Wang Yuanlong expressed approval for the clinical performance of AccuPulse's PFA system this time and shared that his most intuitive feeling was that the catheter’s adjustable loop design was excellent, making the operation process extremely smooth, which greatly enhanced confidence and efficiency during the procedure. The adjustable loop design can flexibly adapt to the personalized anatomical structures of patients, achieving better contact and laying a solid foundation for the success of the surgery. The catheter combines excellent operational feel with flexible adaptability, and its promotion and application will bring good news to more patients with arrhythmia, pushing interventional treatment for arrhythmia to new heights.

Flexible Adaptation, Precise Adhesion:Its unique 7.5F adjustable loop diameter design can flexibly match the pulmonary vein anatomy of different patients, achieving personalized adaptation and significantly enhancing the adaptability and safety of the operation.

Intelligent docking, real-time feedback:The system is equipped with AccuPulse's independently developed impedance contact prompting technology, which can monitor the catheter-tissue contact quality in real time, clearly indicate the contact status, assist operators in achieving stable and reliable catheter manipulation, and provide a solid guarantee for precise ablation.

Efficient Integration, Streamlined Processes:The circular catheter integrates mapping, modeling, and ablation functions, rapidly constructing a three-dimensional electroanatomical model of the heart during surgery, precisely locating lesions, and significantly reducing reliance on additional high-density mapping catheters in traditional surgeries. This not only decreases surgical complexity but also saves on consumable costs, offering atrial fibrillation patients a safer, more effective, and less invasive treatment option.

Safer:7.5F Ultra-thin Catheter, Reducing Tissue Damage

More Stable:Smart Snap Tips for More Precise Operation

More flexible:Adjustable loop diameter (15-20mm or 20-25mm) to meet different clinical choices.

AccuPulse Medical Technology Co., Ltd. has received approval for its disposable cardiac pulsed field ablation catheter, overcoming the challenges of stability and anatomical adaptability in PFA ablation catheters, providing a precise and reliable solution for pulmonary vein isolation (PVI). The unique 7.5F adjustable loop diameter design of the AccuPulse cardiac pulsed field ablation catheter flexibly adapts to different anatomical structures of the pulmonary veins. Intelligent contact indication and flexible electrode selection give operators complete control, enabling accurate pulsed field ablation!

AccuPulse is an innovative company focused on the research, development, and industrialization of advanced technologies in the field of cardiac electrophysiology. The company’s core team has a strong background in electrophysiological technology and extensive experience in the industrialization of medical devices, consistently striving to provide safer, more efficient, and more convenient treatment options for patients with arrhythmias such as atrial fibrillation.

This time, AccuPulse^®Single-use Cardiac Pulsed Field Ablation Catheter and AccuBlator^®The successful application of the cardiac pulsed electric field ablation system at the Sixth People's Hospital of Shanghai marks a milestone achievement for AccuPulse in the field of innovative electrophysiological treatment technology.

The Department of Cardiology at the Sixth People's Hospital of Shanghai is one of the earliest large clinical medical centers to establish a cardiovascular specialty in China. It is one of the most academically influential disciplines domestically, a component of the national key discipline, and a key discipline at both Shanghai Jiao Tong University School of Medicine and the hospital level. It is also a training base for coronary intervention and arrhythmia intervention under the National Health Commission. The first director of the department, Professor Dong Chenglang, the founder of cardiology in China, was the earliest editor of the first domestic monograph on heart disease, "Practical Cardiology." He is the founding figure of the cardiovascular and electrocardiology specialties in China and an internationally renowned scholar in cardiovascular diseases with profound knowledge.

Professor Shen Chengxing, the current academic leader, holds a high academic position in the field of cardiology in China. He is highly recognized by his peers and currently serves as a standing director of the Chinese Society of Microcirculation, a member of the Chinese Medical Doctor Association, a member of the Shanghai Branch of the Chinese Medical Association, a fellow of the European Society of Cardiology (FESC), a reviewing expert for the *Chinese Journal of Cardiology* and the *Chinese Medical Journal*, one of the forum chairs of the Chinese International Forum at the OCC conference, and an interventional training mentor at the Ministry of Health Coronary Intervention Training Base. Currently, the department has more than 10 members with senior titles such as professors/associate professors, 18 members with doctoral degrees, and 93 open beds available for patients. The department specializes in the diagnosis and treatment of various complex, difficult, and critical cardiovascular diseases.

Doctor of Medicine, Chief Physician, Doctoral Supervisor, graduated from Fudan University School of Medicine. Currently serves as the Director of the Heart Center at Shanghai Sixth People's Hospital, member of the Cardiovascular Branch of the Chinese Medical Association, member of the Cardiovascular Branch of the Chinese Doctors Association, Deputy Head of the Metabolic Cardiovascular Disease Group of the Cardiovascular Physicians Branch of the Chinese Doctors Association, Standing Director of the Chinese Society of Circulation, Standing Committee Member of the Cardiovascular Branch of the Chinese Stroke Society, Standing Committee Member of the Straits Critical Care Society, member of the Cardiovascular Branch of the Shanghai Medical Association (Deputy Head of the Cardiac Intervention Group), FESC, Chairman of the OCC Rehabilitation Forum, and Head of the Working Group of the Cardiac Prevention and Rehabilitation Center of the Cardiovascular Physicians Branch of the Shanghai Doctors Association. Has participated in research projects including the National 973 Program, National Natural Science Foundation projects, and multiple provincial and ministerial level projects; has led five national-level projects and three provincial and ministerial level projects. Has published over 30 Chinese and English articles in domestic and international core journals, including 15 SCI papers. Is one of the earliest doctors in China to perform interventional diagnosis and treatment of coronary heart disease and acute myocardial infarction via the radial artery, with rich clinical experience. The main research directions are the mechanisms and prevention of coronary heart disease and molecular mechanisms of heart failure.

Doctor of Medicine, Deputy Chief Physician of the Cardiology Department at Shanghai Sixth People's Hospital. Youth Committee Member of the Shanghai Heart Rhythm Society, Committee Member of the Cardiovascular Internal Medicine Branch of the Shanghai Stroke Society, Member of the Arrhythmia Group of the Cardiovascular Physicians Branch of the Chinese Medical Doctor Association, and Member of the Left Atrial Appendage Occlusion Expert Committee of the Asian Heart Rhythm Society. Long engaged in clinical work related to cardiac pacing and electrophysiology, with extensive clinical experience in the diagnosis and treatment of arrhythmias. Skilled in catheter ablation for tachyarrhythmias (such as atrial fibrillation, atrial flutter, atrial tachycardia, supraventricular tachycardia, premature ventricular contractions, ventricular tachycardia, etc.), pacemaker therapy for bradyarrhythmias (including leadless pacemaker implantation), device therapy for heart failure (CRT-P/D), and left atrial appendage occlusion. Independently completed over 6,000 cases of catheter-based radiofrequency ablation for various types of tachyarrhythmias and has been invited to assist multiple hospitals across provinces and cities in performing electrophysiological radiofrequency ablation surgeries. Presided over or participated in more than ten national natural science projects and other research initiatives, published over 20 academic papers, and contributed to academic monographs such as "Catheter Ablation for Atrial Fibrillation," "Atlas of Catheter Ablation for Atrial Fibrillation," and "New Advances in Cardiopulmonary Cerebral Resuscitation."