Home Hopstem Announces Phase I Clinical Data for iPSC-Derived Cell Therapy hNPC01 Injection

Hopstem Announces Phase I Clinical Data for iPSC-Derived Cell Therapy hNPC01 Injection

Dec 18, 2025 15:01 CST Updated 15:01
Hopstem Biotechnology

iPSC Cell Therapy Product Developer

Bayer

Pharmaceutical Product R&D Developer

BlueRock Therapeutics

Induced Pluripotent Stem Cell (iPSC) Therapy Developer

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On December 11, 2025, Hopstem Biotechnology was invited to present its independently developed technology at the 2025 International Society for Stem Cell Research (ISSCR) International Symposium on Pluripotent Stem Cell-Derived Therapies.18-Month Follow-Up Data from Phase 1 Clinical Trial of iPSC-Derived Cell Therapy Product hNPC01 Injection. This year's event focuses on the development and commercialization of pluripotent stem cell-derived products entering the clinical stage, bringing together top global forces and the latest clinical breakthroughs in this field.
During the conference, leading international companies in pluripotent stem cells (PSC), such as Bayer/BlueRock Therapeutics, Vertex Pharmaceuticals, Neurona Therapeutics, and Astellas, also announced significant clinical progress in their PSC-derived cell therapy programs, covering multiple indications including neurological, metabolic, and neurodegenerative diseases. Meanwhile, several internationally renowned scientists, including Professor Hideyuki Okano, Professor Takehiko Kaneko, and Dr. Jane Lebkowski, shared the latest clinical results in myocardium, spinal cord injury, and ophthalmology. In-depth discussions were held on key topics such as clinical safety and efficacy evaluation, commercialization readiness, GMP-grade pluripotent stem cell lines, large-scale production capabilities, and late-stage clinical development pathways.

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Dr. Fan Jing, founder and CEO of Hopstem Biotechnology, was invited to give a special report. The excellent efficacy data of hNPC01 in the Phase I clinical study conducted in China has attracted high attention from researchers and industry peers, marking that the high-quality clinical research of pluripotent stem cells in China is also at the forefront internationally.


"The scientific research and clinical achievements showcased at this year's symposium demonstrate that multiple pluripotent stem cell-derived therapies are entering the next critical stage of development," said Dr. Fan Jing. "We are honored to share the clinical data of hNPC01 on this global platform—a leading product in terms of progress and market scarcity, these forebrain neural precursor cells have already shown significant potential in treating long-term motor dysfunction after stroke in Phase I clinical trials. Hopstem Biotechnology will continue to advance the global clinical development of hNPC01, bringing safe, effective, accessible, and groundbreaking regenerative medicine therapies to patients with unmet clinical needs such as stroke and traumatic brain injury."

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