Clarify Medical Launches Home Light Therapy System for Stubborn Plaque Psoriasis and Files IPO Prospectus

VCBeat (WeChat ID: vcbeat) has learned that Clarify Medical recently launched the Clarify Home Light Therapy System (hereinafter referred to as the “Clarify Home Phototherapy System”), a home-use phototherapy device for treating plaque psoriasis.

Clarify Medical is a medical device company headquartered in San Diego, USA, dedicated to developing innovative technologies and products with a focus on chronic skin conditions. In 2017, the company’s flagship product, the Clarify Home Phototherapy System, received FDA approval for the treatment of the following skin conditions: psoriasis, vitiligo, atopic dermatitis (eczema), seborrheic dermatitis, and leukoderma.

Psoriasis, commonly known as "niupixuan" in Chinese, is a chronic inflammatory skin disease with a strong genetic predisposition. It is characterized by a prolonged clinical course and a tendency to relapse, with some cases remaining incurable throughout the patient's lifetime. Psoriasis primarily affects young and middle-aged adults, significantly impacting their physical health and psychological well-being. Clinically, it presents mainly with erythema and scaling. Lesions can occur all over the body but are more common on the scalp and the extensor surfaces of the limbs, often worsening in winter. In addition to pharmacological treatments, common therapeutic approaches for psoriasis include herbal baths, herbal vapor therapy, fumigation and steam therapy, and photodynamic therapy.

The Clarify Home Phototherapy System is a form of photodynamic therapy and a type of physical therapy, primarily used to treat generalized or localized refractory psoriasis. Based on narrowband UVB (a specific band within the ultraviolet spectrum), the system utilizes visible and invisible light from natural sunlight or artificial sources, filtering out harmful UV wavelengths that can damage the skin. By targeting the affected areas, it regulates cutaneous microcirculation, accelerates the elimination of metabolic waste and toxins, and promotes normal skin keratinization, thereby achieving therapeutic outcomes.

Clarify Medical conducted a 10-week clinical trial on eight adult patients with stable plaque psoriasis. The trial results demonstrated improvement in lesions among patients using the Clarify home phototherapy system, along with a reduced incidence of erythema, more pronounced efficacy, lower carcinogenic risk, and reduced costs. Furthermore, the system is suitable for special populations, including pregnant women and children.

It is understood that the Clarify Home Phototherapy System is the first and only connected smart device in the field of dermatology. This product connects to an app on the patient’s smartphone, allowing specialized physicians to provide online guidance and prescribe appropriate phototherapy dosages, frequencies, and durations for specific skin conditions. Furthermore, all treatment records, including photographs and patient-reported outcomes, are stored in the backend system for access and use by both patients and physicians. These advantages reduce healthcare costs for patients, improve treatment efficacy, and significantly alleviate the clinical burden on physicians.

“Lawrence D. Eichenfield, MD, Professor of Dermatology and Pediatrics at the University of California, stated: ‘The Clarify Home Topical Phototherapy System innovates upon traditional medical devices by synchronizing monitoring and management with handheld devices, offering a user-friendly and effective solution that enables patients to receive personalized care without leaving home.’”

George Mahaffey, President and Chief Executive Officer of Clarify Medical, stated, “We aim for the Clarify Home Phototherapy System to become the preferred choice for novel targeted therapy among patients with psoriasis, vitiligo, and other chronic skin conditions.”

(Compiled by Feng Yutong)