Revenue of $94.193 billion, a year-on-year increase of 6% ——Johnson & JohnsonBeneath the robust appearance of this report card lies a passive strategic contraction: the growth rate of the orthopedics business.Dropped to 1.1%, becoming the only department in the medical technology sector to lose momentum, forcing the company to announce the spin-off of DePuy Synthes to save the overall valuation system.
Latest! Johnson & Johnson Plans to Spin Off Orthopedics Business, Another $10 Billion Spin-Off Deal
In contrast,Abbott$44.328 billion in revenue, though only half of Johnson & Johnson's, faces even more pressing transformation anxiety: IVD business year-on-yearDown 4.3%, becoming the only position that has been lost. To this end, the company splurged $21 billion to acquire Exact Sciences, attempting to fill the performance vacuum left by the retreat of the COVID-19 dividend with a "growth through acquisition."
Under the dual pressures of evolving global healthcare demands and deepening centralized procurement, the response strategies of the two giants have diverged significantly:Johnson & Johnson Chooses "Cutting Losses" to Divest Low-Growth Assets, Abbott Bets on Emerging Tracks with "Blood Transfusion for a New Heart". AndChina RegionAs one of the important variables, it is accelerating this differentiation — Johnson & JohnsonOrthopedics Market Share Suffers a Major Setback Here, Abbott Diagnostics Business Endures$400 Million Centralized Procurement Impact。
When the existing business hits a ceiling, this strategic shift crucial for survival has officially begun.
Top Medical "Report Card" ReleasedJohnson & Johnson: Strong in Cardiovascular, "Weakest" in Orthopedics
Johnson & JohnsonFull-year revenue for 2025$941.93 billion, year-on-yearIncrease by 6%,Among them:- Innovative Pharmaceutical Business:Is the main engine of the company's growth, accounting for65%The above,CampRevenue of $60.401 billion, a year-on-year increase of 6%.
- Medical Technology Business: Revenue of $33.792 billion, a year-on-year increase of 6.1%. The cardiovascular business, with $8.93 billion in sales and a year-on-year growth rate of 15.8%, became the biggest highlight. It is not only the only business unit in the medical technology department to achieve double-digit growth but also propelled the overall medical device business to new heights.
▲ Johnson & Johnson 2025 Fiscal Year Data Overview (Unit: $ Million)
In the innovative pharmaceuticals business, there are a total of six subdivisions:
- Tumor:Johnson & Johnson's most outstanding performance in the innovative drug business, with annual revenue reaching $28.308 billion, a year-on-year increase of 20.1%.Darzalex (Daratuzumab): This CD38 monoclonal antibody is Johnson & Johnson's "magic needle" in the multiple myeloma market, with annual sales reaching $14.351 billion, a year-on-year increase of 21%. Carvykti (Cilta-cel):AndLegend Biotech CollaborationThe BCMA CAR-T therapy developed achieved annual sales of $1.887 billion, surging 95.9%;
- Immunology:Revenue of $15.728 billion, a year-on-year decrease of 11.8%. The decline was mainly attributed to core products.Stelara (Ustekinumab) Faces Biosimilar Launch Impact, Sales Drop 41.3% Year-over-Year to $6.078 Billion;
Neuroscience:Revenue of $7.837 billion, a year-on-year increase of 10.1%;
Pulmonary Hypertension:Revenue of $4.437 billion, a year-on-year increase of 3.6%;
Infectious Diseases:Revenue of $3.241 billion, a year-on-year decrease of 4.6%;
Cardiovascular and Metabolism:Revenue of $3.778 billion, a year-on-year increase of 6.1%.
Medical technology mainly focuses on cardiovascular, orthopedics, surgical, and ophthalmology businesses.- Surgical Operation:As the largest business in medical technology, revenue reached $10.137 billion, a year-on-year increase of 3%.
- Cardiovascular:Divided intoElectrophysiology,AbiomedAndShockwave MedicalThree Core Segments, Annual Sales Surge Year-over-Year15.8%To89.3Billion US dollars。
- Orthopedics:Revenue of $9.258 billion, a year-on-year increase of 1.1%;
- Ophthalmology:Revenue of $5.468 billion, a year-on-year increase of 6.3%.
CardiovascularBusiness Strong Rise, Specifically: AbiomedAndShockwave MedicalAs Johnson & Johnson nears300The key outcome of a billion-dollar acquisition investment,2025Annual sales have broken through10USD billion mark. Electrophysiology business achieved7%Increased year-over-year to56.3Billion US dollars, itsVaripulse PFAGrowth exceeding Q2300%。In contrast,Orthopedic Services2025OnlyMicro-increment1.1%To92.6Billion USD, achievedPerformance in the medical technology sectorThe Weakest Department。Johnson & Johnson has2025Year10Announced in the month that the orthopedics business will be spun off into an independent company.. This means that in the future, the focus of Johnson & Johnson Medical TechnologyTurning to high-growth areas such as cardiovascular and surgical robotics.During the teleconference, Johnson & Johnson emphasized that currently, approximately50%'s medical technology assets have been deployed in high-growth markets, compared to2018Year's20%Achieve a significant improvement. As the orthopedic business is spun off into an independent company (expected in2027By the middle of the year, the share of high-growth markets will further increase to70%The above.Abbott:IVD is the only business segment that declined.
AbbottFull-year revenue for 2025$44.328 billionYuan, year-on-yearIncrease by 5.7%, wherein:- Medical Device Business:Abbott's largest business segment, with revenue of $21.387 billion, increased by 12.6% year-over-year, accounting for a significant proportion.48%;
- Diagnostic Services: Revenue of $8.937 billion, a year-on-year decrease of 4.3%, was also Abbott's only declining business, accounting for 20%.;
- Nutritional Products Business: Revenue of $8.451 billion, a year-on-year increase of 0.4%,Accounting for 19%;
- Pharmaceutical Business Revenue: $5.536 billion, a year-on-year increase of 6.6%, accounting for 13%。
▲Abbott 2025 Financial Data Overview (Unit: $ million)AbbottCultivateThe medical device sector is the largest in share (USD 21.387 billion) and also the fastest-growing (YoY +12.6%) business segment.▲Abbott Medical Devices Business 2025 Fiscal Year Data Overview (Unit: $Million)
Among themHeartBlood VesselBusinessCampRevenue of $12.379 billion, a year-on-year increase of 9.4%, still stands out when looked at separately.The Largest Business Across the Company, accounting for 28%.- Rhythm Management: Revenue of $2.649 billion, a year-over-year increase of 10.9%;
Electrophysiology: Revenue$2.764 billion, a year-on-year increase of 12%;
Heart Failure: Revenue of $1.448 billion, a year-over-year increase of 13.2%, representing the fastest-growing business in cardiovascular.
Cardiovascular (Vascular): Revenue of $2.995 billion, a year-over-year increase of 5.6%.
Structural Heart: Revenue of $2.523 billion, a year-over-year increase of 12.3%.
It is worth mentioning thatIn the field of electrophysiology, Abbott has obtained two important approvals. One isVolt™PFASystemAlreadyObtainFDAApproval, thisAlsoYesAbbott inThe First Pulsed Field Ablation Device Launched in the United States。Secondly, Abbott'sTactiFlex™DuoAblation CatheterObtainCECertification, the catheter through radiofrequency andPFAProvides treatment for patients with atrial fibrillation.IVD is Abbott's only declining business in 2025.Revenue of $8.937 billion, a year-on-year decrease of 4.3%。Still in the post-epidemic era"Withdrawal Reaction", among whichThe decline in COVID-19 testing business has brought$500 millionThe impact.
▲Abbott IVD Business 2025 Fiscal Year Data Overview (Unit: $Million)
Traditional Diagnosis:Revenue of $5.36 billion, a year-on-year increase of 2.4%, is Abbott's largest IVD business.YesStable Basic Disk;
Rapid Diagnosis:Revenue of $2.454 billion, down 18.1%, is the decline in IVD.The most serious business,This is precisely the sector where Covid-19 testing-related products were previously concentrated;
Molecular Diagnostics:Revenue of $517 million,Year-on-year-0.7%;
Point-of-care diagnosis:Revenue of $606 million, up 3.1% year-over-year%,Mainly due to the clinical adoption of high-sensitivity troponin testing。
In response to the decline, Abbott's approach was also very direct:Mergers and Acquisitions。20November 2025On the 20th,AbbottSplurge$21 billion in cash to swallow cancer early screening leader Exact Sciences,BecomeThe Largest M&A in the Medical Device Industry in 2025, which will also be Abbott's largest strategic acquisition in nearly a decade.Exact Sciences maintained a high growth rate of 20% year-over-year for the same period, and Abbott urgently needs this sizable piece to bolster its financial report. Of course, in terms of the early screening track, the merger and acquisition by Abbott is not only aimed at filling the growth vacuum left by the shrinking COVID-19 business but also represents a strategic game regarding the industry's next decade.China Region: VBP Remains a "Hot Topic"When it comes to the China region, it is inseparable fromCentralized Procurement。IVD IndustryInThe overall decline in 2025 will reach its largest value in five years.AbbottMentioned on the conference call:In the Chinese market, Abbott bore approximately$400 millionThe impact of centralized procurement performance.In previous years, due to the impact of centralized procurement, only the testing price of Abbott China fell.However, the testing volume is still growing continuously, but this year from the testing...Fee reduction, "unbundling of test packages" under surprise inspections, and mutual recognition of test results,Not only did the price drop, but the testing volume also fell, leaving IVD companies with almost no room for cushioning.Abbott admitted in its report that China's centralized procurement projects are mostly concentrated in areas where Abbott's market share exceeds40%The dominant field.As for the specific data in the China region, it was not disclosed. However, during the conference call, Abbott stated, “With the expansion of the product portfolio, China currently accounts for only a portion of the company's total revenue.Less than 6%”。This "6%" does not emphasize diagnostic services alone,Roughly estimated, Abbott China's revenue is less than 27 billion US dollars.However, from AbbottFrom the $23 billion acquisition of Exact Sciences, Abbott is "moving away."Traditional IVD Business, Investment TowardsHigh-margin, high-growth cancer detection may also bring significant changes to the business in China in the future.For 2026, Abbott CEO Robert Ford gave a clear judgment on the diagnostics business:Acceleration(加速)After experiencing the most intensive and severe external shocks in two years, Abbott believes:Diagnostic Business Is Moving Past the Toughest Phase.In addition,Cardiovascular Track, China Region Despite Being Affected byInterventional Consumables(Stent、Balloon、Pacemaker)、Cardiac ElectrophysiologyImpact of centralized procurement, Abbott's performance still on the rise. However, on October 31 last year,Gansu Provincial Medical Security Bureau Announces Plan toPullHead Start on the Inter-Provincial Alliance for Centralized Bulk Procurement of Heart Valves, causing Abbott's valve market share to erode.Johnson & JohnsonThe Most Affected in 2025 IsOrthopedics Field, the poor revenue was mainly affected by business restructuring, China's Volume-Based Procurement (VBP), and competitive pressures in some niche markets. Among these, in China: Johnson & Johnson's spinal business market share dropped from 16% toLess than 5%。Especially the tariff at the beginning of the yearBattle Down, Johnson & Johnson's orthopedic product line in China has been severely impacted. Taking knee replacement implants as an example, the rise in import costs has led to higher end-user prices, causing a noticeable decline in procurement volume at some hospitals. To address cost pressures, Johnson & Johnson is accelerating the localization of production at its Suzhou factory and plans to30% of Surgical Instrument Production Capacity Shifted to China, while launching20% Layoff Plan.However, in the end, Johnson & Johnson chose to spin off its orthopedics business, DePuy Synthes, into an independent company.The goal is to achieve formal independence by mid-2027.Looking back, in 2025, when centralized procurement has squeezed industry profit margins and traditional businesses have completely disappeared, the giants that thrive will not just be those who "compete internally" in their existing operations. Instead, they will have successfully navigated through precise strategic shifts to upgrade productivity during the industry downturn.The most valuable statement in Abbott's report is not about revenue, but rather it demonstrates the breathtaking engine replacement accomplished amidst turbulent waters. Johnson & Johnson, on the other hand, has opted for a direct spin-off to complete its "pivot" in the orthopedics sector.