AccuPulse PFA System Achieves Clinical Milestone with First Zero-Fluoroscopy Atrial Fibrillation Ablation in Wenzhou

Recently,The Second Affiliated Hospital of Wenzhou Medical UniversityAs one of the first clinical application units in China,Director of Cardiology, Dr. Jia LiLead its teamApplication of AccuPulse^®Single-use Cardiac Pulsed Field Ablation Catheter and AccuBlator^®AccuPulse Medical Technology Co.Ltd's cardiac pulsed field ablation system successfully performed a pulsed field ablation (PFA) procedure on a patient with atrial fibrillation.

The surgical patient was an 84-year-old female with paroxysmal atrial fibrillation. According to preoperative examination, the left atrial diameter was 44mm. Ablation was performed using AccuPulse's 15-20mm variable loop cardiac pulse ablation catheter. The total duration of the surgery was 81 minutes, including 4 minutes for catheter modeling and mapping, and 39 minutes for pulmonary vein ablation. The surgery was completed successfully.

Preoperative Substrate Mapping and PostoperativeMatrix MappingFigure

This surgery marks the first zero-radiation atrial fibrillation ablation procedure performed by AccuPulse in the Wenzhou region, as well as the first fully zero-radiation atrial fibrillation surgery in China following the market release of the AccuPulse pulsed field ablation (PFA) system. The entire procedure was completed under the guidance of a three-dimensional electro-anatomical mapping system and intracardiac echocardiography (ICE), completely avoiding X-ray radiation. After venous puncture, the interatrial septum puncture was performed under ICE guidance to establish access to the left atrium. Subsequently, the PFA catheter was inserted for three-dimensional mapping and substrate mapping of the left atrium. The ablation sequence was as follows: RIPV (42 applications), RSPV (25 applications), and the left pulmonary vein common trunk (68 applications). Additionally, 12 ablations were performed on the superior vena cava (SVC). Throughout the procedure, ICE combined with the three-dimensional system was used to continuously assess catheter contact quality in real time. The entire surgery was successfully completed under zero-radiation conditions, signifying a new phase of green electrophysiology in the field of arrhythmia interventional treatment.

PVI Ablation Diagram

Pulmonary Vein and SVC Ablation Trajectory Map

The operator gave positive feedback on the excellent performance of the AccuPulse Cardiac Pulsed Field Ablation System, specifically highlighting its significant advantages of "sufficient energy and powerful impact," which ensured efficient ablation while demonstrating outstanding clinical efficacy. The entire surgical process was perfectly coordinated with 3D mapping and intracardiac echocardiography (ICE). Impedance monitoring and contact sensing functions provided strong support to the operator. Based on high recognition of the system's overall performance, the operator shared constructive optimization insights from the perspective of pursuing the ultimate operational experience. This feedback will drive the technology towards a safer and more precise direction, significantly shortening the learning curve and improving surgical efficiency. We believe that the system will continue to inject stronger momentum into the thriving field of green precision electrophysiology.

Flexible Adaptation, Precise Adhesion:Its unique 7.5F adjustable loop diameter design can flexibly match the pulmonary vein anatomy of different patients, achieving personalized adaptation and significantly enhancing the adaptability and safety of the operation.

Intelligent docking, real-time feedback:The system is equipped with AccuPulse's self-developed impedance contact indication technology, which can monitor the catheter-tissue contact quality in real time, clearly indicate the contact status, assist operators in achieving stable and reliable catheter manipulation, and provide a solid guarantee for precise ablation.

Efficient Integration, Streamlined Processes:The circular catheter integrates mapping, modeling, and ablation functions, rapidly constructing a three-dimensional electroanatomical model of the heart during surgery, accurately locating lesions, and significantly reducing the reliance on additional high-density mapping catheters in traditional surgeries. This not only decreases surgical complexity but also saves on consumable costs, providing atrial fibrillation patients with a safer, more effective, and less invasive treatment option.

Safer:7.5F Ultra-thin Catheter, Reducing Tissue Damage

More Stable:Smart Snap Tips for More Precise Operation

More flexible:Adjustable loop diameter (15-20mm or 20-25mm) to meet different clinical choices.

AccuPulse Medical Technology Co., Ltd. has received approval for its disposable cardiac pulsed field ablation catheter, overcoming the challenges of stability and anatomical adaptability in PFA ablation catheters. It provides a precise and reliable solution for pulmonary vein isolation (PVI). The AccuPulse cardiac pulsed field ablation catheter features a unique 7.5F adjustable loop diameter design, offering flexibility to address various anatomical structures of the pulmonary veins. Intelligent contact sensing and flexible electrode selection give operators complete control, enabling accurate pulsed field ablation!

AccuPulse is an innovative company that focuses on the research, development, and industrialization of cutting-edge technologies in the field of cardiac electrophysiology. The company's core team possesses a deep background in electrophysiological technology and extensive experience in the industrialization of medical devices, consistently striving to provide safer, more efficient, and more convenient treatment options for patients with arrhythmias such as atrial fibrillation.

This time, AccuPulse^®Single-use Cardiac Pulsed Field Ablation Catheter and AccuBlator^®The successful application of the cardiac pulsed electric field ablation system at the Second Affiliated Hospital of Wenzhou Medical University marks a milestone achievement for AccuPulse in the field of innovative electrophysiological treatment technologies.

Medical Doctorate from the University of Hamburg, Germany; Master's thesis advisor. Chief physician and deputy director of the Cardiology Department. Serves as the deputy chairperson of the Zhejiang Medical Association’s Electrophysiology and Pacing Branch, a member of the Right Heart and Pulmonary Circulation Group under the Cardiovascular Branch of the Chinese Medical Association, and a member of the Electrophysiology Innovation Group under the Cardiac Rhythm Branch of the Chinese Biomedical Engineering Society. First-level operator for catheter ablation of atrial fibrillation and certified non-radiation operator. Participated in the Chinese consensus on non-radiation catheter labs and related technologies, and was among the first in the province to establish a non-radiation ablation operating room. First or corresponding author of clinical research articles published in Europace (3 articles in 2020 and 2024), JACC-EP, JCE, etc. Serves as a reviewer for multiple SCI journals. Conducted study visits at Asklepios Hospital Hamburg, Eppendorf Hospital affiliated with the University of Hamburg, St George Hospital at the University of London, and LKH Hospital in Austria. Completed over 3,500 cases of non-radiation ablation treatments for various types of arrhythmias, including more than 1,200 cases guided by unipolar electrogram techniques for non-radiation transseptal puncture, achieving high success rates without complications, with relevant clinical research published in Europace. In 2017, successfully treated a high-risk pregnant woman with incessant tachycardia due to a para-Hisian accessory pathway, which was reported by multiple media outlets. Assisted dozens of hospitals across China in conducting non-radiation surgeries.