Home Innovative Collaboration: Chuangxin International and BeiGene Sign Strategic Cooperation Agreement to Advance Organoid-Based Drug Development

Innovative Collaboration: Chuangxin International and BeiGene Sign Strategic Cooperation Agreement to Advance Organoid-Based Drug Development

Dec 20, 2021 17:54 CST Updated 17:54

On December 20, the signing ceremony for strategic partners of the BeiGene Bio-Island Innovation Center was grandly held. During the ceremony, Chuangxin International Biotechnology (Guangzhou) Co., Ltd. and BeiGene (Guangzhou) Innovation Technology Co., Ltd. officially signed a framework agreement for strategic cooperation, marking a new chapter in their partnership.


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Ceremony Site


Signing of Strategic Cooperation Agreement


Under the cooperation agreement, ChipIntelli International and BeiGene have entered into a strategic partnership to jointly establish an organoid-based new drug R&D technology platform. By integrating new drug development with organoid technology, the two parties will collaboratively develop an intelligent organoid-based drug evaluation system, providing pharmaceutical companies with one-stop solutions. This initiative is expected to significantly promote the global application of organoid technology in new drug discovery and drug evaluation.


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Mr. Huang Min, Chairman of Chuangxin International, Signs on Behalf


Earlier this month, the Center for Drug Evaluation (CDE) included organoids for the first time in its guidance on nonclinical pharmacology studies for gene therapy products, specifically within the context of validating gene and cell therapies. The document states: “Organoids can provide assessments of efficacy and safety for genetically modified cell therapy products.”


As a highly valued next-generation disease model and drug screening platform, organoid technology helps validate therapeutic efficacy and establish standards and norms for the gene and cell therapy industry, further facilitating new drug development and disease treatment.


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The collaboration between ChipOne International and the BeiGene Innovation Center will help drive the sustained development of the entire biopharmaceutical industry chain, enhance original innovation capabilities in biomedicine, facilitate access to clinical resources, and demonstrate corporate commitment and responsibility in promoting high-quality industry development.


In the future, both parties will fully leverage their respective comparative advantages to explore the industrial value chain encompassing organoid-based biomarker discovery, high-throughput screening of active compounds, preclinical efficacy evaluation of cell and gene therapy drugs, and drug safety assessment. They aim to establish an application ecosystem for organoid-based drug R&D technology platforms, jointly promote the application of organoids in new drug development, and provide integrated solutions for pharmaceutical enterprises covering scientific research, industrialization, and commercialization, thereby facilitating high-quality industry development.


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Group Photo of Strategic Partner Signing Ceremony


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About BeiGene


Beijing Innovatech (Guangzhou) Co., Ltd. aims to bridge science and capital, fostering scientist- and entrepreneur-centric innovation. By leveraging BeiGene’s established advantages and resources in preclinical research, clinical development, process development, and large-scale manufacturing, the company incubates advanced scientific concepts and accelerates the success of innovative enterprises in scientific research, industrialization, and commercialization. It seeks to break through the long-standing bottlenecks in China’s biopharmaceutical industry, address entrepreneurial pain points, support regional economic development, fundamentally transform the industry value chain for innovative drug R&D and patient accessibility, and further accelerate the establishment of an innovation ecosystem.


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About Chuangxin International


Chuangxin International Biotechnology (Guangzhou) Co., Ltd. is an innovative biotechnology enterprise centered on organoid technology. Established in Macau in 2016, the company is headquartered at the Accelerator in Guangzhou Development District and serves as the Guangdong Provincial Engineering Technology Research Center for Organoids. It currently operates R&D centers in Beijing, Shanghai, Guangzhou, Macau, and Milan, Italy; holds controlling interests in three subsidiaries; and conducts business across 22 provinces and autonomous regions in China. Chuangxin International is dedicated to personalized therapy, new drug development, and regenerative medicine, boasting a complete organoid industry chain and serving as an international hub for the organoid industry.