Angelexo Scientific Emerges as a Dark Horse in Neurorehabilitation with Groundbreaking Single-Limb Exoskeleton Robot

The State Council’s “14th Five-Year Plan for the Protection and Development of Persons with Disabilities” points out that China currently has more than 85 million persons with disabilities, accounting for 6.34% of the total population. According to the “China Stroke Center Report 2020,” approximately 17.8 million people aged 40 and above in China suffered from stroke in 2020, imposing a heavy burden on families and society. Stroke is a common disease that seriously threatens human health and life, with a disability rate exceeding 80% and a severe disability rate exceeding 40%. Neurological rehabilitation for patients with brain injury is one of the primary rehabilitation goals for those with physical functional impairments. It directly affects patients’ activities of daily living and quality of life. In particular, the recovery of lower-limb walking and motor function represents the most urgent need for patients to achieve “illness without disability, and disability without incapacity,” enabling their early return to family and society.

For lower-limb gait dysfunction in patients with hemiplegia due to brain injury, clinical practice has demonstrated that robot-assisted therapy is a highly effective rehabilitation approach. Lower-limb rehabilitation training robots can help patients with gait impairments improve balance, correct gait patterns, and ultimately restore normal walking ability.

Currently, clinical rehabilitation medicine mostly relies on manual “maneuver”-assisted training. The inefficiency of “one-on-one” or “many-to-one” treatment models poses challenges for patients, rehabilitation physicians, and clinical institutions. Suspended rehabilitation robots have been adopted in some rehabilitation centers; however, in addition to being bulky and expensive, these devices restrict patients’ limbs during training, resulting in poor comfort and low compliance.

Mobile rehabilitation robots are designed based on bionic principles and integrated with ergonomics, with corresponding actuators installed at major joints. When worn by patients, the robot’s movement aligns coaxially with the human body’s degrees of freedom, thereby enabling more efficient assisted rehabilitation training.

Among the numerous enterprises developing lower-limb rehabilitation robotic products,Anjilai Technology (Hangzhou) Co., Ltd. (hereinafter referred to as "Anjilai Technology")After four years of painstaking research, leveragingGlobal Leading LiteStepper™ Single-Leg Rehabilitation Training Robot “Breaks Through the Competition”, establishing differentiated competitiveness.

Anjielai Technology was established in December 2017 and is a company focused onIntelligent Robotics Company Applying Brain Science. The company focuses on the field of intelligent rehabilitation, based on addressing critical clinical needs, and has honed its intelligentAutonomous Gait Learning, Human-Machine Interaction, Redundant Sensor Fusion, Osteomuscular Metabolic Information Sensing, Bionic Exoskeleton Design...key industrialization platform technologies for intelligent robots, and has developed a series of innovative products based on these technologies. Anjielai Technology currently possessesOver 70 Intellectual Property Rights, among whichHeld/Filed over 20 invention patents.

Angelai Technology's headquarters is located inHangzhou, inBeijingBranch offices are established,Zhengzhou, HenanThe company has established subsidiaries. With its foundation in China and a global perspective, it operates inSeattle, USAEstablished an Overseas Business Division responsible for FDA approval and registration in the United States, CE certification in Europe, and overseas market promotion.

AngelTech’s inaugural product is the LiteStepper™ single-limb lower extremity rehabilitation training robot. This is aThe World's First Single-Leg Rehabilitation Medical Robot, for use under the guidance of trained healthcare professionals in medical institutionsHemiplegia PatientsUndergo rehabilitation training; this product hasReceived approval from the National Medical Products Administration for classification as a Class II innovative medical device.It is reported that,"Mobile Robot-Assisted Lower Limb Gait Training"It has been included in the medical insurance catalogs of multiple provinces and municipalities. Beijing Medical Insurance Item Code: MZZ00001.

LiteStepper™ Single-Leg Rehabilitation Training Robot

LiteStepper™ Single-Leg Rehabilitation Training Robot MainWorking PrincipleBy collecting gait data from the patient’s unaffected limb, the system identifies movement intentions and analyzes and learns the gait characteristics of the unaffected side to drive the LiteStepper™ single-limb rehabilitation robot. This enables coordinated rehabilitation training for the affected limb, facilitating bilateral combined motor relearning during walking to support recovery. Long-term gait rehabilitation helps patients gradually restore their normal walking pattern.

Compared with other lower-limb rehabilitation robots, AngelTech’s LiteStepper™ single-lower-limb rehabilitation training robot featuresProactive, Personalized, Intelligent, and Precisesuch advantages:

• "Stimulate and guide patients to actively participate in rehabilitation."The core of neurological rehabilitation is active rehabilitation. Lower limb rehabilitation robots primarily focus on passive training, neglecting active rehabilitation.Significance of Neurorehabilitation; AngelTech's single-leg robotic system, grounded in the fundamental principles of neurorehabilitation, emphasizes harnessing patients' active participation in rehabilitation, maximizing the proactive guidance role of the unaffected limb, and promoting the awakening of neural control awareness and enhancement of motor function in the affected limb.

• Intelligent Adaptive Personalized Gait Control.Lower-limb rehabilitation robots mostly adopt programmed gait control, which reduces patient comfort as well as the efficiency and effectiveness of rehabilitation; Angele Technology’s single-lower-limb robot, throughLearning Gait Characteristics of the Unaffected Limb, facilitating personalized movements of the affected limb that are synchronized with the healthy limb, thereby effectively addressing the issues of programmed or unnatural gait patterns inherent in traditional rehabilitation training.

• The robot and the patient's unaffected limb form a natural bilateral synergy.Most lower-limb rehabilitation robots employ body weight support or walking assistance, which diminishes patients’ proprioception; Angele Technology’s single-leg robot frees the patient’s unaffected limb and allowsPatient ambulates independently, allowing patients to move under the influence of natural gravity, which can evoke homologous muscles in the affected limb to perform symmetrical movements, thereby improving motor control, proprioception, and coordinated movement of various muscle groups in the affected limb, with the aim of achieving autonomous walking as a rehabilitation goal.

• Covers the full-cycle rehabilitation of hemiplegia patients.Hemiplegic PatientsFull Disease CourseBoth can utilize Angelei Technology's single-leg robotic system for neurological rehabilitation and gait correction.

• High cost-effectiveness.Leveraging Angelai Technology’s proprietary core platform for intelligent robotics, the LiteStepper™ single-lower-limb rehabilitation training robot offers a cost-effective alternative to other products that often cost millions, while ensuring quality, efficacy, and patient experience.A cost advantage of approximately 1/3 to 1/2。

  
  

LiteStepper™ Single-Leg Rehabilitation Training Robot in Use

For healthcare professionals and hospitals,Under traditional clinical pathways, early ambulation training requires a minimum of three medical or auxiliary staff members to implement, whereas LiteStepper™ enables training with only one rehabilitation therapist. Meanwhile, the use of a single-limb robotic device encourages patients’ active participation in rehabilitation, reducing the physical exertion required of therapists. This improves personnel efficiency and patient throughput in the rehabilitation department, while minimizing repetitive labor for rehabilitation therapists and related medical staff.

For patients,The entire robotic system is equipped with up to eight sensors and pre-installed intelligent algorithms, enabling it to provide real-time, personalized training based on the patient’s condition for improved rehabilitation outcomes. The rehabilitation process is moreIntelligent and personalized, offering an enhanced experience while reducing the reliance of rehabilitation training on the expertise level of rehabilitation physicians.

Since the prototype of the LiteStepper™ single-limb rehabilitation training robot was developed in 2018, it has undergone five iterations, resulting in superior performance, a more comfortable user experience, and enhanced clinical outcomes. In addition, the company is advancing the regulatory registration and filing for multiple intelligent neurological rehabilitation robotic products, with expectations to launch them on the market in the third quarter of this year.

Currently, Anjielai Technology has partnered withYangzhi Rehabilitation Hospital Affiliated to Tongji University (Shanghai Sunshine Rehabilitation Center), The First Affiliated Hospital of Zhejiang University, The Second Affiliated Hospital of Zhejiang University, Hangzhou First People's Hospital, Jiaxing No. 1 Hospital, Zhengzhou University Rehabilitation Hospital (The Fifth Affiliated Hospital), University of British Columbia Rehabilitation Centre, CanadaEstablished clinical research/trial partnerships with dozens of domestic and international medical institutions to jointly advance the academic research and clinical application of intelligent neurorehabilitation robots on a global scale.

Driven by a spirit of innovation, Angelai Technology has assembled a team of industry experts spanning robotics, artificial intelligence, advanced medical materials, and neurological rehabilitation medicine. By closely aligning with urgent clinical market demands, the company has established robust technical barriers for the industrialization of intelligent robots. Angelai is currently dedicated to advancing the industrialization and commercialization of its series of intelligent robots, providing healthcare institutions, physicians, and patients with intelligent, systematic, and comprehensive solutions for neurological rehabilitation.

In terms of financing, Anjielai Technology secured tens of millions of yuan in Pre-A funding in early 2022, led by Shiyue Capital and participated by Shanghai Xuyuan.(For details, please refer to “[Exclusive] Angelei Technology Secures Tens of Millions in Pre-A Financing to Accelerate the Industrialization of Intelligent Neurorehabilitation Robots”)Currently, the company isSeeking tens of millions in the next round of financing, for use inIterative optimization of existing products, development of new products, regulatory approvals for domestic and international markets, and market promotion。