Shineyo Medical Showcases RhythPulse®-PFA System at OCC 2026 with Strong Clinical Data and Expert Endorsements

The conference has invited the First People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine.Professor Liu Shaowen, Zhongshan Hospital Affiliated to Fudan UniversityProfessor Nie ZhenningServe as co-hosts to host the event.

In their opening remarks for this symposium, the two professors pointed out that China has over 20 million patients with atrial fibrillation. Although traditional ablation demonstrates significant efficacy, it still faces challenges such as procedural complexity, a steep learning curve, and risks of complications. Pulsed Field Ablation (PFA) technology, leveraging its tissue-selective ablation mechanism, enables precise myocardial ablation within milliseconds while sparing the esophagus, blood vessels, and nerves, thereby truly realizing the clinical aspiration of “green electrophysiology.”

ShineyoMedical, as a pioneering innovator in the field of electrophysiology in China, its independently developedRhythPulse® Pulsed Field Ablation System, is the first PFA system approved in China that integrates multi-channel, large-field focal, and targeted ablation capabilities. The system has been selected by Shanghai“New and Superior Drugs and Medical Devices” Catalog and Pudong New Area Recommended Catalog of Innovative Drug and Medical Device Products, and completed the first batch of clinical applications at multiple authoritative centers in China, fully demonstrating the independent innovation and industrialization capabilities of Chinese medical device enterprises in the high-end electrophysiology field.

Professor Qin Mu further elaborated on the characteristics and applicable scenarios of pulsed ablation catheters of different sizes. Among them,10-mm large-tip focal catheters demonstrate superior performance in linear ablation (e.g., tricuspid isthmus, mitral isthmus), whereas 15-mm, 20-mm, and 25-mm circular catheters are more suitable for pulmonary vein isolation, posterior wall isolation, and patch ablation.Drawing on specific clinical cases, he demonstrated the re-ablation strategy using this catheter in patients with recurrent atrial fibrillation after prior ablation, highlighting its ability to achieve precise block even in complex electrophysiological substrates such as recovered pulmonary vein potentials and restored conduction across the mitral isthmus.

Furthermore, Professor Qin emphasized the importance of intraoperative catheter selection and combined use. For instance, in a case of mitral isthmus ablation, ten energy deliveries with a 15-mm catheter failed to achieve complete block, whereas switching to a 10-mm large-focal catheter resulted in bidirectional block after only four energy deliveries. He noted that the RhythPulse®-PFA catheter not only offers highly efficient immediate ablation capabilities but also provides new tools and strategic insights for the individualized treatment of complex atrial arrhythmias.

Professor Sun Jian provided a detailed demonstration of various contact and ablation strategies using the circular pulsed-field ablation catheter. For instance, when achieving adequate contact with the anterior wall of the right superior pulmonary vein is challenging, a “side-contact plus selective electrode discharge” approach can be employed; for the posterior wall, a “stamp-like” contact technique is recommended to enhance stability. During tricuspid isthmus ablation, adjustable deflectable sheaths can facilitate either “side-contact” or “catheter straightening” maneuvers to avoid entanglement with chordae tendineae, thereby improving ablation efficiency. He also emphasized that intraoperative electric field interference may cause “pseudo-displacement” artifacts in 3D mapping systems, and that selecting partial electrode discharge can effectively localize such interference around the active electrodes, thus ensuring precise catheter localization.

In addition, Professor Sun emphasizedThe RhythPulse®-PFA cathode features the unique advantage of patented unilateral coated electrodes: discharge occurs only at the myocardial contact surface, reducing ineffective discharge into the blood, thereby lowering the risk of hemolysis and microbubble formation, and enhancing the safety of procedures such as posterior wall isolation.。Professor Sun Jian further validated the operational experience of the RhythPulse® catheter in arrhythmia surgery through five cases, providing practical evidence for the clinical promotion of PFA technology.

Professor Shi Ruizheng, Xiangya Hospital of Central South UniversityAdvantages of the Novel Pulsed Ablation Energy Catheter RhythPulse®-PFA in the Clinical Treatment of Atrial FibrillationHe systematically elaborated on the iterative advancements and improvements of PFA technology compared to traditional radiofrequency ablation. He pointed out that, as a non-thermal ablation energy source, PFA can selectively damage cardiomyocytes while sparing surrounding tissues such as blood vessels, nerves, and the esophagus, thereby offering superior safety profiles for perivascular structures, the esophagus, and the phrenic nerve.

Professor Shi provided a detailed introduction toUnique Design Advantages of the RhythPulse®-PFA Circular Catheter。This catheter is developed based on a mature mapping catheter platform, compatible with mainstream 3D mapping systems, and features a gentle learning curve; its circular electrode array can flexibly adapt to varying pulmonary vein anatomies, enabling segmental pulmonary vein isolation, with transmural lesions achieved through minimal rotational overlap. Notably,RhythPulse®-PFA circular catheter features an exclusive patented single-sided coated electrode that discharges only from the outer myocardial contact surface, effectively reducing ineffective discharge into the blood.，thereby reducing the risk of hemolysis and acute kidney injury.

Drawing on the application cases at Xiangya Hospital, Professor Shi summarized that PFA has become the preferred energy source for nearly half of atrial fibrillation ablation centers in Europe. As the first domestically developed unilateral coated electrode-targeted ablation catheter, RhythPulse®-PFA features an exclusive 10mm specification that can also serve as a large-focal catheter for linear ablation, providing a “Chinese solution” that balances safety and efficacy for complex atrial arrhythmias.

The discussion session was hosted by Union Hospital, Fujian Medical UniversityProf. Zhang FeilongShanghai Sixth People's HospitalProfessor Huang Dong, Shanghai Pudong New Area People's HospitalProf. Han SuxiaServe as a panelist for discussion.

Following the presentations by the aforementioned speakers, the experts engaged in in-depth discussions and exchanges, sharing their respective experiences and insights from multiple perspectives. The frequent intellectual exchanges sparked further wisdom, effectively promoting the integration and advancement of academic viewpoints.

The conference was a resounding success, fully demonstrating the superior performance and stability of PFA technology in real-world clinical settings, marking a critical step toward the regional promotion of comprehensive atrial fibrillation treatment technologies.