DPM Launches Groundbreaking Ruiyan Series 3D 4K Fluorescence Endoscopy System with Global First-in-Class True8 CMOS Technology

DPM, incubated by the CAS Key Laboratory of Molecular Imaging, has been committed to its journey as a leader in the post-precision era, striving forward into the new era with the collective strength of the DPM team. Since 2019, the company has launched its Chaoyan, Zhiyan, and Huiyan series endoscope product lines in the Chinese market. On December 22, 2022, DPM’s globally pioneering Ruiyan series 3D 4K fluorescence endoscopic camera system, featuring the proprietary Zhizhen 8 CMOS technology, received marketing approval from the Guangdong Provincial Medical Products Administration, marking a new chapter in DPM’s high-end endoscopy medical device product portfolio!

Benefiting from favorable policies and iterative product upgrades, domestic high-end endoscope manufacturers have entered a golden period of development to break foreign monopolies. DPM has continuously expanded its product matrix for endoscopic camera systems while successfully laying out product lines such as 4K 3D fluorescence endoscopes and 3D endoscopes. The Ruiyan Series Zhihen 8, featuring CMOS technology, offers ultra-high resolution and high-fidelity 3D imaging. By employing pixel fusion technology, it maximizes the restoration of fluorescence images without compromising white-light performance, delivering high-quality image fusion with super 4K precision.

DPM’s Ruiyan Series 4K 3D Fluorescence Endoscope better assists surgeons in achieving precise spatial localization, reducing operational errors and shortening the learning curve during procedures such as vessel skeletonization, lymph node dissection, margin assessment, distance estimation, and anastomotic reconstruction. Intraoperative navigation with fluorescent molecular imaging enables millisecond-level visualization of the in vivo distribution of fluorescent contrast agents, thereby assisting physicians in detecting minute lesions, identifying their location and morphology, and performing precise resections. Since its clinical introduction, fluorescence endoscopy, as a functional endoscopic technology, has received unprecedented attention and promotion across various subspecialties, with its clinical applications continuously expanding and becoming more widely accessible.

In the emerging field of fluorescent molecular imaging, industry stakeholders are racing to develop imaging system products. Among them, DPM boasts comprehensive advantages spanning imaging methodologies, imaging systems, basic research, and clinical translation. The DPM team has long engaged in in-depth interdisciplinary collaborations with multiple top-tier (Grade A tertiary) hospitals and research institutes in China. Related work was recently published in Nature Biomedical Engineering, a prestigious journal in the field of biomedical engineering technology. Upon publication, the study received acclaim from international peers, including Dr. P. Pàmies, Editor-in-Chief of Nature Biomedical Engineering, and Professor H. Choi of Harvard Medical School, who hailed it as “the first-in-human.”

Ruiyan Series 3D 4K Fluorescence Endoscopic Camera System is the world’s only holographic 3D product capable of dual optical path imaging, including white light and fluorescence. Through holographic acquisition and display rather than post-processing synthesis, it delivers precise 3D visualization without dizziness. Each optical path outputs in 4K, with resolution further upgraded to achieve 4096P imaging. Featuring proprietary adaptive depth-of-field adjustment, it eliminates the need for manual focusing.

DPM’s Ruiyan Series 3D Endoscopic Imaging System features proprietary 785 nm high-efficiency excitation, resulting in low tissue thermal effects, enhanced fluorescence image contrast, and improved patient safety. Current state-of-the-art international research has adopted excitation light below 800 nm, such as 780 nm and 785 nm near-infrared light, achieving favorable application outcomes and publishing high-quality scientific literature in international journals.

The host system features enhanced AI algorithms that highlight details and contours of lesions, tissues, and blood vessels. It incorporates proprietary automatic exposure control, fluorescence fusion, and fluorescence sensitivity enhancement algorithms to precisely delineate lesion boundaries and accentuate minute lesions as well as extremely fine lymphatic vessels. The exclusive 360° intelligent smoke evacuation function ensures clearer images in 3D stereoscopic displays, minimizing visual field interference caused by intraoperative smoke.

DPM’s Ruiyan Series 4K 3D Fluorescence 3D Endoscopic Camera System embodies the years of dedicated effort by its R&D team and incorporates valuable clinical feedback from leading frontline experts. Its features, including storage design, seamless switching, and department-specific modes, are tailored to meet clinical needs, providing clinicians with a novel experience. The Ruiyan Series features a unique open-platform architecture with strong functional expandability, allowing it to be used in conjunction with DPM’s fluorescence molecular imaging system and intelligent smoke evacuation system, thereby delivering a comprehensive solution for clinical practice.

DPM has maintained close collaborations with top medical experts both in China and abroad, accumulating decades of R&D experience in the integration of medicine and engineering, and achieving systematic outcomes as well as technological breakthroughs in key areas. DPM will continue to deepen its expertise in the field of molecular imaging, delivering more high-quality, innovative solutions for clinical practice, and contributing to the advancement of healthcare in China.