On April 6, Guangzhou Dongfanglue Biotechnology Co., Ltd. (hereinafter referred to as “Guangzhou Dongfanglue”) signed a strategic cooperation agreement with Baidu Health. It is reported that the two parties will establish a long-term strategic partnership through this signing. In the near term, they will collaborate on innovative projects centered around an auxiliary protective product against respiratory infectious diseases—IgM nano-immunoglobulin protective spray, branded as Adong “Liquid Mask” (nasal spray)—leveraging digitalization to drive new growth in Guangzhou Dongfanglue’s innovative marketing efforts.
In recent years, breakthroughs in digital technologies such as the internet, big data, and artificial intelligence have gradually accelerated innovation in the healthcare industry. In the post-pandemic era, public perceptions of health management and medication purchasing habits continue to evolve. Against this backdrop, building on Adong’s innovative “liquid mask” project, both parties will progressively deepen their collaboration: Guangzhou Dongfanglue will leverage its proprietary technology platform and R&D pipeline for innovative products, while Baidu will capitalize on its AI expertise, jointly driving the digital and intelligent transformation of pharmaceutical product development, innovation, and marketing.

Adong “Liquid Mask” is an auxiliary protective product against COVID-19 jointly developed by Dongfang Lue Group and the Institute of Microbiology, Chinese Academy of Sciences. It is recommended for administration as a nasal spray. Its main active ingredient is pentameric IgM-type nano-immunoglobulin, which demonstrates higher prophylactic efficacy compared to traditional IgG-type immunoglobulins. The product has completed production process development, efficacy validation tests, and safety trials at multiple authoritative laboratories. Experimental results indicate that it exhibits excellent binding affinity against respiratory infectious viruses. Upon spraying, it adheres to skin and mucosal surfaces to form a protective layer, blocking viruses through the formation of aggregated particles, with protective effects lasting for 24 hours.

“In the post-pandemic era, face masks continue to play a vital role in daily life; however, conventional protective masks are often stuffy and uncomfortable. In response to market demands and user pain points, and to provide the general public with ‘respiratory relief,’ Oriental Lue Group has invested tens of millions of yuan in R&D to develop Adong ‘Liquid Mask.’” stated Chen Mingjian, founder of Oriental Lue Group. “Adong is particularly suitable for occasions such as attending large conferences or spring travel. ‘Brushing teeth, washing face, and spraying Adong’ will become a new morning personal hygiene routine for the middle class. As China’s leading tech-driven health service platform, Baidu Health boasts strong technical capabilities and a vast user base. We hope this collaboration will help bring Adong more effectively to market, benefiting the general public.”

He Mingke, Senior Vice President of Baidu Group and President of Baidu Health Business Group, stated, “As a necessity in the post-pandemic era, face masks play a significant role in public health events and personal protection. However, they also bring considerable inconvenience, such as impeding breathing and obscuring smiles. Adong’s ‘Liquid Mask’ effectively addresses these issues by providing protection while allowing free breathing. Safeguarding health and discovering happiness—this is also the shared pursuit of Baidu Health and Oriental Strategy.”
Baidu’s Pharmaceutical Enterprise Services address the pain points of pharmaceutical companies by providing end-to-end solutions. Leveraging the vast search demand on Baidu Health, it helps pharmaceutical companies establish their brand presence while facilitating patient education through diverse product formats and the accumulation of science-based content, thereby shortening the communication pathway between pharmaceutical companies and patients.
The Adong Liquid Mask project serves merely as the starting point for this collaboration. In the future, both parties will leverage their respective strengths to jointly explore new technologies and solutions for disease prevention, diagnosis, and treatment, promote innovative research in frontier medical science and technology along with the translation of its achievements, and ensure that the public shares in the benefits of these developments.