Home InsideTracker Files for IPO: Harvard-MIT-Backed Aging Biomarker Platform Serving Over 100,000 Users and Raising $100M+

InsideTracker Files for IPO: Harvard-MIT-Backed Aging Biomarker Platform Serving Over 100,000 Users and Raising $100M+

Feb 03, 2024 08:00 CST Updated 08:00
Inside Tracker

Nutrition and Health Platform Service Provider

We live in a world rich in scientific information but lacking personalized guidance.

 

People are easily overwhelmed by a flood of health information from their social circles, academia, and industry, making it difficult to identify the correct course of action. If intelligent algorithms could accurately pinpoint individuals’ specific health needs and provide precise, straightforward solutions, the “guessing game” would be eliminated from the general public’s anti-aging journey.

 

InsideTracker is one of the “puzzle solvers” in this space. The company is dedicated to building “4P Medicine” for healthy individuals—namely, Predictive, Personalized, Preventive, and Participatory.

 

InsideTracker was incubated and established in 2009 by experts in aging, genetics, and biometrics from Harvard, MIT, and Tufts. Its team comprises professionals including scientists, physicians, nutritionists, and exercise physiologists. By analyzing users’ blood biomarkers, DNA, lifestyle, and nutritional habits, the company provides guidance to help users better maintain health and combat aging.


Incubated by top scientists from Harvard University, MIT, and Tufts University


Dr. Gil Blander, Founder and Chief Scientist of InsideTracker, was driven to “help people live healthier, longer lives” by a profound personal experience. The untimely death of a family member when he was young left him shocked and heartbroken, inspiring his commitment to advancing the field of human longevity. Since then, he has collaborated with pioneers in aging research, such as MIT biologist Leonard Guarente and Harvard geneticist David Sinclair, to conceive and refine a personalized nutrition and lifestyle platform powered by automation and intelligent algorithms.

 

Dr. Gil Blander earned his Ph.D. in Biology from the Weizmann Institute of Science and completed his postdoctoral research at the Massachusetts Institute of Technology, where he focused on aging research. An expert in nutrition, biomarker analysis, athletic performance, biochemistry, and aging, Dr. Blander holds multiple patents and has published peer-reviewed articles in these fields. He enjoys an international reputation for his work in the fundamental biology of aging and for translating his discoveries into novel methods for detecting and preventing age-related diseases. His work has been featured in The New York Times, Forbes, the Financial Times, and The Boston Globe.

 

InsideTracker also boasts profound technical expertise in algorithms, data, and information technology. Slava Brodskiy, Senior Vice President of Technology, Engineering, and Security, has over 25 years of proven success in information technology and resource management, with extensive experience in web product development, e-commerce, IT management, quality assurance and technical operations, customer relationship management, data analytics systems, and business intelligence. Renée Deehan, Vice President of Science and Artificial Intelligence, brings more than 15 years of experience in developing artificial intelligence and computational biology methods and applying them to large-scale health data for drug discovery and preventive medicine.

 

At InsideTracker, Dr. Gil Blander leads a team of experts in biology, computer science, nutrition, and exercise physiology.He co-founded the company in 2009 alongside leading scientists from Harvard University, the Massachusetts Institute of Technology, and Tufts University, specializing in aging, genetics, and biostatistics.The company has attracted numerous professors from world-renowned universities and experts with decades of experience in anti-aging research.

 

Among them, David A. Sinclair, a member of the Scientific Committee, is a Professor of Genetics at Harvard Medical School and Co-Director of the Paul F. Glenn Center for Biology of Aging Research at the same institution. Sinclair is renowned for his research on aging and epigenetics. In 1993, he met Leonard P. Guarente, a Novartis Professor of Biology at the Massachusetts Institute of Technology (MIT) in the United States, while in Australia. Intrigued by Guarente’s research direction focusing on genes involved in the regulation of aging, Sinclair applied for a postdoctoral position in Guarente’s laboratory.

 

Notably, more than a decade later, Sinclair and his former mentor Guarente have reunited at InsideTracker, jointly joining the company’s Scientific Advisory Board.

 

Furthermore, the team’s scientific advisory board comprises renowned industry experts, including Dr. Jeffrey B. Blumberg, Professor at the Friedman School of Nutrition Science and Policy at Tufts University; David Katz, Founding Director of the Yale-Griffin Prevention Research Center at Yale University; Roger A. Fielding, Professor at Tufts University School of Medicine; and Kate Wolin, Partner at PACE Healthcare Capital.


Emphasizing the Personalization and Scientific Basis of Anti-Aging


The company’s anti-aging services are centered on “personalized biomarker analysis + data-driven health guidance.”Moreover, its health guidelines are based on an analysis of users’ blood, DNA, lifestyle, and physiological indicators such as height, weight, age, sex, and race, with testing dimensions that far exceed the scope of annual blood tests.

 

To handle this massive volume of data, InsideTracker’s team of scientists, bioinformaticians, and technology experts developed an engine called “SegterraR” for data mining and visualization. SegterraR is capable of mining extensive biomarker and scientific data, laying the foundation for the automated algorithmic engine, SegterraX.

 

SegterraX is InsideTracker’s flagship achievement, developed through more than 70 person-years of scientific effort by a multidisciplinary team led by experts in nutrition, medicine, bioinformatics, genetics, and information technology. As an automated algorithmic engine, it powers the InsideTracker platform by integrating user-provided data—including biomarkers, demographics, personal profiles, lifestyle habits, and genetic information—with rules established by scientists based on their analysis of over 2,500 peer-reviewed scientific publications, a demographic database of more than 180,000 healthy individuals, a database of over 8,000 unique foods, and the professional expertise of the team and its Scientific Advisory Board, to generate personalized intervention plans for each individual.

 

InsideTracker’s anti-aging services focus on being “data-driven,” “customizable,” and “personalized.”InsideTracker leverages advanced algorithms and extensive scientific databases to not only identify the “clinically normal” ranges for biomarkers but also reveal personalized optimal biomarker intervals for each user. This helps users discover in which areas they have already achieved optimal status, where there is room for improvement, and whether their biomarker data indicates an increase or decrease in their biological age.

 

The InnerAge 2.0 testing panel developed by the company serves as a testament to its “personalized” approach. This panel analyzes 17 biomarkers in men and 13 biomarkers in women to calculate users’ biological age. Data show that biomarker levels are not only significantly correlated with age, but this correlation also varies by sex. For example, hsCRP (high-sensitivity C-reactive protein) is significantly correlated with age in men but not in women; therefore, it is not included in the female testing panel. Although analyzing additional biomarkers could potentially improve accuracy and stability, InsideTracker will not include them solely to achieve visual “gender balance” in the absence of scientific rationale and demonstrated validity.

 

Following the above cases, it is not difficult to see that,InsideTracker also places great emphasis on the scientific rigor of its services.InsideTracker’s recommendation engine integrates user data with current scientific literature and in-depth bioinformatics analysis to generate personalized nutrition, supplement, fitness, and lifestyle recommendations tailored to individual needs. Building on this foundation, the company employs an impartial rating system that ranks each recommendation from one to five stars (with five stars indicating the strongest support) based on the strength of scientific evidence supporting its efficacy, as derived from peer-reviewed studies.


Exponentially Increase the Precision and Customization of Action Plans


During the specific service process, users first need to select the health and longevity plan that best suits them. At this stage, InsideTracker arranges a 15-minute online consultation with company experts to answer questions, provide product demonstrations, and help determine which plan best meets the user’s needs. The company offers multiple packages for selection. Among them, the Ultimate Package provides the most comprehensive service, covering up to 48 blood biomarkers across 10 key healthspan domains.

 

Users can then have their blood drawn at a testing facility or at home through InsideTracker’s mobile phlebotomy service. The company also offers DNA testing. For this service, users receive a DNA test kit, perform an oral swab at home, and mail it back to the company. The DNA test kit analyzes 20,000 genetic markers to reveal the user’s genetic potential for up to 38 health traits, identifying how DNA influences heart health, metabolism, cognition, hormonal balance, inflammation, gut health, and more.

 

In addition, through the InsideTracker mobile application, users can integrate real-time physiological data from fitness trackers such as Fitbit or Garmin, along with self-reported data on sleep and stress, with blood and DNA biomarker data.This “blood + DNA + fitness tracking” data combination adds exponential precision and customization to the InsideTracker Action Plan.

 

Subsequently, users will receive the analysis results on the application. In the detailed view of the blood test, InsideTracker’s comprehensive analysis of the user’s blood biomarkers includes visual tracking, trend information, recommendations for optimizing each biomarker, and accessible explanations of the underlying scientific principles.

 

Based on the test results, users can select their desired outcomes, such as improving physical fitness, maintaining overall health, or reducing stress. InsideTracker will inform users which factors have the greatest impact on their aging status, how these factors will influence the achievement of subsequent goals, and when retesting is required.

 

Users can track progress, check in, and set reminders on their personal health analytics dashboard to stay motivated and adhere to their plans. The dashboard integrates the entire process of assessing health status, viewing personalized recommendations, and monitoring implementation progress. Finally, users are required to update their blood analysis every 3–6 months to track improvements in health status and determine next steps.

 

In terms of data privacy and security, InsideTracker is fully HIPAA-compliant and SOC 2 certified, ensuring that users’ personal data—including blood biomarkers, DNA, and vital signs—are thoroughly encrypted, anonymized, and de-identified.


Completed $15 million Series B financing


On November 18, 2021, InsideTracker announced that its first scientific paper had been published in Scientific Reports, a peer-reviewed, authoritative journal under the Nature Portfolio. Titled “Longitudinal Analysis of Biomarker Data from a Personalized Nutrition Platform in Healthy Subjects,” the paper represents the culmination of nine years of effort by the entire scientific team, staff, and Scientific Advisory Board.

 

This study conducted long-term follow-up on biomarker data from over 1,000 users of varying ages on the InsideTracker platform. The results demonstrated that InsideTracker effectively improves health outcomes through personalized nutritional recommendations, with 14 of the 17 biomarkers most frequently deviating from the normal range among the user cohort showing long-term improvement. Furthermore,This study confirms that InsideTracker’s algorithm can select effective nutritional interventions for individuals based on their unique blood data, personal profiles, and preferences.

 

On September 8, 2022, InsideTracker completed a $15 million Series B financing round. The round was led by PeakBridge, with participation from OurCrowd, Cornucopian Capital, and BASF Venture Capital. The funds will be used to strengthen research and development efforts, expand marketing, and support operations, thereby enabling InsideTracker’s solutions to help people around the world live healthier and longer lives.According to Crunchbase's official website, InsideTracker has raised a total of $18.2 million (approximately RMB 130 million) in funding to date.

 

Among the many players in the field of aging biomarker testing, InsideTracker distinguishes itself with comprehensive assessments combining blood tests, DNA analysis, fitness tracking, and self-reported data, along with data-driven, scientifically backed personalized recommendations. It focuses on delivering “comprehensive,” “intelligent,” and “personalized” anti-aging services.According to its official website, more than 100,000 customers rely on InsideTracker to extend their healthspan.Meanwhile, compared with most companies in the sector that are still at the seed or angel investment stage, InsideTracker is clearly ahead in its fundraising progress, which also suggests that it may accelerate the commercial expansion of its products at a faster pace. So, can InsideTracker ultimately achieve its goal of “making people around the world healthier and live longer through personalized services”? Only time will tell.