SEIMEI Senmei Files for IPO: Validated by WuXi AppTec, Pioneering High-Net-Worth Personalized Nutritional Anti-Aging Solutions

“Resisting Aging” has always been a topic that sparks endless imagination.

It is reflected in the ambrosia and elixirs of ancient Greek mythology, the divine beasts and immortality drugs in the Classic of Mountains and Seas (Shan Hai Jing), Tang Sanzang’s flesh and the Peaches of Immortality in Journey to the West, and the exotic lychee fruits in In Search of the Supernatural (Sou Shen Ji).... Thousands of years ago, people harbored the cherished wish for longevity and eternal youth. Millennia later,““Anti-aging” has been “disenchanted,” gradually transitioning from the fantasies of mythology into reality, becoming a hot sector in the health industry backed by scientific evidence and theoretical research.

According to data from iMedia Research, the global anti-aging market size grew from $139.5 billion in 2015 to $216 billion in 2021, with a year-on-year growth rate of 11.1% in 2021. The global anti-aging market is expected to maintain a high growth rate in the future, offering substantial room for development. Forbes data suggests that China’s anti-aging market has a potential growth space of RMB 100 billion. Against the backdrop of consumption transformation and upgrading in China, along with residents’ increasing emphasis on health and wellness, the domestic anti-aging industry is poised for continued expansion.

Among them,SEIMEI is an innovative enterprise dedicated to building a high-end, personalized nutrition and anti-aging technology brand.By developing proprietary nutritional anti-aging supplements, providing patients with digital health management solutions, offering professional nutritionist consultation services, and building communities to host offline events,Yimei has built a closed-loop model of “products + digitalization + services,” creating a “health showcase” for the second half of life for the new middle-aged population.

Since its inception, the company has completed research and testing on low glycemic index (GI=46, diabetes-friendly) products in collaboration with the China National Research Institute of Food and Fermentation Industries.Experimental Collaboration with WuXi AppTec; partnered with Rechangchang Research Institute to establish an expert think tank and a thought leadership summit in the field of comprehensive nutrition for anti-aging; collaborated with Ipsos, a globally renowned research firm, to conduct third-party user surveys, continuously gathering authentic consumer feedback to enhance products and services...Grounded in cutting-edge scientific thinking, Senmei leverages clinical case studies, basic experiments, reviews, and meta-analyses as evidence-based references to support ingredient formulations with clear, transparent, high-level experimental evidence, while continuously exploring and deepening its expertise in product innovation and service improvement.

Yisen Yimei COO Ren PeiyuHolds a Master’s degree from Peking University and an EMBA from CEIBS; is an expert in enterprise digitalization and marketing digitalization. Previously served as President of Marketing Intelligence at Mininglamp Technology, Strategic Product Manager at Baidu, and Consultant at Accenture, with deep expertise in the field of digital innovation.

When discussing the origins of their startup, Ren Peiyu introduced another key figure at Senmei—Yan Zhao, a Peking University alumnus, former colleague, and current co-founder serving as Chief Executive Officer.

Yisen Yimei CEO Yan ZhaoA serial entrepreneur with a track record of success, he graduated from the College of Chemistry and Molecular Engineering at Peking University. He previously served as Co-founder and Co-President of Mininglamp Technology, Product Manager in R&D at Procter & Gamble, and Strategic Management Consultant at Mars & Co., possessing extensive experience in product development and team management.

Ren Peiyu and Yan Zhao previously worked together at a renowned artificial intelligence technology company, focusing on enterprise digitalization. They jointly dedicated themselves to helping businesses build digital platforms to enhance internal operational efficiency and external marketing effectiveness. Their expertise in digitalization has laid a solid foundation for Senmei’s digital innovation.

Regarding the specific entrepreneurial opportunity, Ren Peiyu stated that it stemmed from the “health crises” they had jointly experienced. In the later stages of his tenure at his previous company, Ren Peiyu encountered health issues, even losing 10 kilograms within a single month. Consequently, already contemplating entrepreneurship, Ren sought to anchor his venture in the health sector, aiming to build a business that was both self-beneficial and socially beneficial. At that time, Yan Zhao was facing similar predicaments; the successive cancer diagnoses of two family members within six months also led Yan to place greater emphasis on the health industry.

From an industry development perspective, the broader health sector was then in its sunrise phase, offering substantial room for growth and representing a field with “significant potential.” At the same time, Ren Peiyu recognized certain issues emerging in the industry’s current development. “In the niche segment of dietary nutritional supplements, most companies treat their products as the entirety of their service offering. However, health supplements and dietary nutritional supplements have a relatively long onset period, often extending beyond three months, which makes user retention a major challenge,” Ren Peiyu explained to VCBeat.

After careful consideration, the team identified “digitalization” as a key breakthrough. Previously, core team members had experience in building consumer-level personal databases for marketing-oriented enterprises. “In fact, user retention in the health industry is similar. If we can establish health databases for consumers and provide personalized guidance on lifestyle and dietary supplement intake based on individual data, we can enhance customer stickiness through digital means and even continuous services beyond product offerings. In this way, user retention will no longer be a thorny issue.”This constitutes Yimei’s unique “Product + Digitalization + Service” model.

In terms of target consumer selection, Senmei has set its sights on high-net-worth individuals aged 40 to 60. “This demographic often bears the burden of caring for both aging parents and young children, facing significant life stressors and declining health. However, most products and services available in the market at that time were predominantly focused on the elderly and the young.” Guided by the belief that “startups should fill market gaps,” Senmei has concentrated on this “new middle-aged” cohort. “Most individuals in this group have begun to physically perceive the effects of aging, leading to a proactive awareness of anti-aging interventions or comprehensive nutritional supplementation. Their needs are relatively inelastic, thereby ensuring a strong repurchase rate,” explained Ren Peiyu.

In terms of product offerings, Senmei has established three major product lines: the Comprehensive Nutrition Line, the Anti-Aging Line, and the Probiotics Line. With the Comprehensive Nutrition Line as its core, the company adopts a “1+X” model to ensure consumers receive comprehensive nutritional supplementation while meeting their personalized needs for nutrition and anti-aging.

To achieve genuine safety and efficacy, Senmei’s global team of scientific experts has conducted in-depth research into cutting-edge concepts, ingredients, and advanced technologies across multiple fields, including global biomedicine and nutritional anti-aging.We have entered into a strategic partnership with a renowned Japanese manufacturing enterprise boasting over 140 years of history, extensive expertise in health and anti-aging, and exceptionally rigorous, high standards in the medical and nutritional supplements sectors. Our products strictly adhere to premium Japanese quality standards throughout all production stages, including formula prototyping, pre-production, product testing, and specialized processing and blending techniques for raw materials (such as probiotics).In raw material selection, Senmei sources from suppliers meeting premium global standards and globally renowned brands.

Comprehensive and balanced nutritional supplementation is a prerequisite for maintaining health and combating aging. “However, this by no means means consuming every nutritional product available on the market in combination. Setting aside the fact that cumbersome routines deter people, more importantly, without scientifically formulated combinations and precise calculations of dosages, such an approach may increase the body’s burden while resulting in unnecessary expenses,” Ren Peiyu explained to VCBeat.

Senmei - 3D Comprehensive Nutritional Supplement Powder Series

andSenmei ONE Pro Health Revitalization Powderis dedicated to addressing this issue. Senmei ONE Pro Health Revitalization Powder features a proprietary "Three-Dimensional Comprehensive Nutrition Formula," which includes 28 vitamins and minerals, high-quality carbohydrates, high-quality proteins, high-quality fats, guar gum dietary fiber (PHGG), probiotic BB536, ribonucleic acid (RNA) nucleotides, chondroitin, and more.Integrates 61 high-quality nutrients into a single, compact sachet to comprehensively support the immune system while providing targeted protection for the brain, bones, muscles, and gastrointestinal tract.It effectively protects the cognitive, motor, and digestive-absorptive functions of individuals who are approaching or have already entered middle age. To enhance the personalization and precision of nutritional supplementation, Senmei has developed upgraded versions of Senmei ONE Pro Health Revitalizing Powder tailored to gender differences, including formulations for men and women.

Yisen Yimei ONE Pro 3D Comprehensive Nutritional Health Revitalizing Powder

Senmei has partnered with the authoritative institution WuXi AppTec to conduct animal clinical trials and related efficacy studies prior to product launch. The experiments involved several control groups, comparing differences in metrics such as grip strength, running duration, running distance, and aging index among subjects of different ages. The results demonstrated that older (elderly) subjects who had taken Senmei products for a certain period showed performance in these metrics comparable to that of younger (middle-aged and young) subjects.

Building on the comprehensive nutritional support provided to consumers through “ONE Pro,” Senmei has also developed anti-aging supplements and probiotic products to meet consumers’ personalized health needs.

In the anti-aging sector,Yisen Yimei's Anti-Aging SupplementsSEIMEI Time CapsuleNMN extracted via yeast fermentation using locally sourced Japanese ingredients, manufactured and processed by a century-old Japanese company, with a purity of up to 99.9%. This product employs a composite formula to enhance the efficacy of NMN. Each capsule containsSEIMEI Time CapsuleContains 160 mg of NMN and 50 mg of “bilberry extract” formulated with a Japanese patent (Patent No. 5324084), including resveratrol and proanthocyanidins, which enhances cellular activity, combats aging, and provides potent antioxidant effects.

Senmei - Time Capsule Product

In its probiotic product line, Yisen Yimei has carefully selected functional probiotics and scientifically formulated them to improve gut microbiota, manage weight, and boost immunity. “Through our own subjective experiences and related research, we have found that regulating gut microbiota is highly beneficial for overall anti-aging and health improvement,” introduced Ren Peiyu.

Senmei – Probiotic Series Products

Currently, the entire series of Senmei's self-developed products has been launched and is available for sale.

Personalized nutritional health management and anti-aging are by no means limited to merely providing consumers with nutritional supplements. Adhering to this philosophy, Senmei has developed a “Product + Digitalization + Service” model., it not only helps consumers improve their physical health through a comprehensive range of self-developed products, but also leverages digitalization to digitize personal health data, thereby guiding consumers to find lifestyles suited to their needs and facilitating the adoption of healthy habits. In addition, Senmei has established a dedicated service team to provide services such as nutritional counseling, continuously tracking and following up on consumers’ health improvements.

In terms of digitalization, Senmei has developed a dedicated mini-program that leverages OCR technology to integrate users’ medical examination reports, hospital test results, and smart bracelet monitoring data, thereby helping them build personal health databases.Based on this database, Yisen Yimei conducts diagnostic assessments of users’ gut health, musculoskeletal health, brain health, and other health indicators. In alignment with consumers’ desired health goals, professional nutritionists, assisted by AI, provide personalized recommendations for lifestyle adjustments, products, and educational courses, thereby formulating a scientifically grounded nutritional health plan.

Throughout the process, Senmei also incorporates personalized guidance and reminder features, providing relevant prompts and suggestions for consumers’ daily activities to enhance their adherence and user stickiness, thereby establishing a data closed loop of “measurement–diagnosis–improvement–remeasurement.”

In addition, Yisen Yimei has developed a specialized tool for generating nutritional plans tailored to dietitians. “After obtaining consumers’ health data, dietitians often need to spend considerable time and effort organizing and analyzing the data before they can provide an understandable analysis report.” To address this challenge, Yisen Yimei internally developed a digital solution that enables dietitians to generate health reports with a single click, based on communication records with consumers and the health data provided. Building on this foundation, dietitians can edit, annotate, and review the reports, thereby delivering more precise guidance and recommendations to users.

In terms of service, Senmei provides nutritional counseling services to consumers who purchase its products, such as one-on-one consultations with dietitians and group nutrition classes. To this end,Yisen Yimei has established a dedicated full-time team of dietitians, all of whom are registered dietitians with years of experience.On one hand, dietitians establish connections with users through platforms such as WeCom; on the other hand, they conduct regular one-on-one online video consultations with consumers to provide more advanced and in-depth advisory and diagnostic services, along with post-consultation follow-up support.

Furthermore, Senmei will establish lifestyle communities for consumers and host offline community events. “Achieving comprehensive anti-aging requires more than just nutritional supplementation and exercise; therefore, our service offerings also prioritize ‘mental well-being’,” stated Ren Peiyu.The new middle-aged cohort serves as the “backbone” in society, the workplace, and the family. While they face substantial pressure, their mental health is often overlooked. Senmei has integrated greater care for this demographic into its online courses and offline community activities, designing initiatives that “bring joy to consumers” and help alleviate stress.

Yisen Yimei User Offline Community Cycling Event

Yisen Yimei User Offline Community Yoga Event

Regarding the future development of the anti-aging sector, Ren Peiyu stated that Chinese consumers are increasingly prioritizing general health and anti-aging, with a growing number of companies entering the market, creating an overall promising outlook. “In fact, there were companies engaged in anti-aging two or three decades ago, but the market at that time was rife with fraudulent firms operating under the guise of ‘anti-aging healthcare,’ leading to a situation where bad money drove out good.”However, the current anti-aging industry is fundamentally different, being underpinned by scientific rationale, theoretical research, and empirical evidence. Moreover, China holds a world-leading position in scientific research on delaying aging and aging clocks, rivaling even the United States. I believe that if the domestic anti-aging industry can rapidly integrate industry, academia, and research, its development pace will be quite rapid.”

Based on current assessments of industry trends, Senmei will continue to deepen its “Product + Digitalization + Service” model in the short term. In the long run, Senmei will persist in exploring personalized anti-aging services, launch aging assessment services, and develop new anti-aging products targeted at emerging consumer needs. We look forward to seeing the remarkable story Senmei will write in the anti-aging sector.