
Nitric oxide (NO) gas is used in clinical therapy. Inhaled NO gas can selectively dilate pulmonary blood vessels and is an effective treatment for pulmonary arterial hypertension (PAH), persistent pulmonary hypertension of the newborn (PPHN), hypoxic respiratory failure (HRF) in newborns, acute respiratory distress syndrome (ARDS), chronic obstructive pulmonary disease (COPD), and other related conditions. In March 2020, two inhaled NO gas therapy products received emergency authorization from the U.S. FDA for the treatment of COVID-19.
In recent years, as research into nitric oxide (NO) has deepened, it has been found to benefit brain health, support the immune system in patients with HIV/AIDS, and aid in the treatment of erectile dysfunction. With further exploration, NO is expected to find application in the treatment of a broader range of diseases.
Ruipu Medical has developed China’s first nitric oxide (NO) therapy device that generates medical-grade NO gas on demand from ambient air using pulsed ionization technology. This innovation addresses the drawbacks of traditional cylinder-based gas sources, reduces treatment costs, and has been granted multiple patents and national awards, holding promise for expanding the application of NO gas in the treatment of a broader range of diseases.
September 23 (Monday)19:30, VCBeat New Product Appreciation Session No. 96, featuringLi Xiang, Marketing Manager at Ruipu Medical; Zhao Chunyu, Clinical Manager at Ruipu MedicalProduct Introduction: Air-Sourced Medical Nitric Oxide (NO) Therapy Device with Instant NO Gas Generation via Pulsed Ionization Technology
1. Safety: Medical-grade high-purity NO
· Multiple Filtration, Efficient Removal of Harmful Gases
· Rigorous Third-Party Environmental Testing
2. Cost-effectiveness: Requires only air
· No Cylinder Gas or Chemical Reaction Apparatus Required
· Generates continuous, unlimited NO using only air
· Filtration device with a lifespan of up to 1,000 hours and extremely low operating costs
3. Ease of Use: Wizard-guided connection, touchscreen operation
· 12.1-inch Full-Screen Operation
· Wizard-Guided Connection Instructions
· Lightweight, Mobile, and Easier to Transfer
· Plug-and-play device with simple and quick replacement of spare parts.
· Scientific Drainage System: Making Life Easier for Medical Staff
4. Intelligence: Medical-grade Sensor Measurement and Control
· Intelligent Detection of Gas Concentration and Changes
· Medical-grade sensors, more precise
· Concentration can be output, adjusted, and controlled on demand
· Intelligent and Safe Weaning Function, Gradually Reducing to 1 ppm
· Real-time Monitoring of the Service Life of Filters and Sensors
5. Convenience: Compact size, lightweight, and long-lasting battery life
· The whole unit weighs only 7.5 kg (for critical care) and 4.8 kg (for sub-critical care), making it easy to carry and go.
· Portable concealed handle, simple and convenient tubing connections, and integrated tubing storage provide a more user-friendly design for operators.
· 120-Minute Long Battery Life, Portable for Easy Transport
6. Effective: Meets clinical usage requirements
· Clinical Practice Has Proven
· Used by 400+ hospitals
· Expert Consensus on Inhaled Nitric Oxide Therapy in Respiratory, Critical Care, and Perioperative Settings
· Suitable for a wide range of users, including adults, children, and newborns.
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Li Xiang
Ruipu Medical | Marketing Manager
Since 2020, I have been working in healthcare marketing, responsible for a range of tasks including online and offline product promotion, product training, event planning, market research, end-to-end management of academic conferences, and client visits.

Zhao Chunyu
Ruipu Medical | Clinical Manager
Member of the Respiratory Therapy Group, Critical Care Medicine Branch, Henan Medical Association; Member of the 1st and 2nd Committees, Pulmonary Rehabilitation Branch, Henan Rehabilitation Medicine Association. Joined Ruipu Medical in 2023 and has organized multiple domestic academic training sessions on nitric oxide. Specializes in the clinical application of iNO across various scenarios.
Ruipu Medical
Shenzhen Ruipu Medical Technology Co., Ltd., established in 2019, is a rising star among Shenzhen’s medical innovation, R&D, and manufacturing enterprises. Leveraging its proprietary air ionization technology for bedside nitric oxide gas preparation, the company has become the domestic pioneer and an internationally leading enterprise in this specialized niche. It was awarded the First Prize for Innovative Invention Products of 2023 by the China Association of Medical Equipment and has obtained approval for innovative medical devices at the Guangdong provincial level.
More than 20 core members of Shenzhen Ruipu Medical’s R&D and marketing teams hail from leading domestic enterprises, bringing over a decade of experience in research and development and marketing. The company has established strong collaborations with academic communities in pediatrics, respiratory medicine, critical care, cardiac surgery, and anesthesiology across China.
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