Giant Biogene Showcases Recombinant Collagen Anti-Aging Innovations at AMWC China 2024

AMWC China 2024 (Aesthetic & Anti-Aging Medicine World Congress), which brought together more than 250 renowned experts from China and abroad, over 200 medical aesthetics brands, and nearly 10,000 industry practitioners, recently concluded successfully in Chengdu. As a global leader in recombinant collagen, Giant Biogene was once again invited to participate, with its Collgene and Collgene Starlight product portfolios dedicated to research on skin rejuvenation care.

During the three-day exhibition, Giant Biogene showcased its star skincare products: Collgene Film Cream, Collgene Film Eye Cream, Collgene Plumping Single-Dose Essence, and Collgene Collagen Mask King.^[1]In addition, the Class II medical device-certified Collgene Starlight products were featured. Furthermore, at its brand booth, Giant Biogene delivered 15 science-based educational sessions over three days. Grounded in scientific principles and supported by practical experience, these sessions centered on three themes: “Biomanufacturing and Applications of Recombinant Collagen,” “Analysis of Collgene Starlight Products,” and “Combination Therapy Protocols with Collgene Starlight.” Through these presentations, Giant Biogene showcased to attending guests its “Original Chinese Ingredient Brand Card,” highlighting the scientific research journey, raw material preparation technologies, and product application case studies of its recombinant collagen.

On the day of the conference opening ceremony, the Giant Biogene booth attracted a visit from Mr. Wang Qian, Deputy Mayor of the Chengdu Municipal People’s Government; Professor Wang Hang, Executive Chairman of AMWC China and Director of the Department of Medical Aesthetics at West China School of Stomatology, Sichuan University; and other dignitaries. Ms. Fang Juan, Senior Vice President of Giant Biogene, provided a detailed introduction to the company’s brand strategy, key scientific breakthroughs, and prestigious honors received.

“Anti-aging” is a highly popular topic, with various brands actively positioning themselves in the anti-aging market. Recombinant collagen is gradually becoming a sought-after ingredient in this sector. This trend is driven, on one hand, by the fact that collagen, as one of the most abundant proteins in living organisms, has long been a research focus in life sciences due to its unique structural and functional properties. On the other hand, companies deeply engaged in the field of recombinant collagen, represented by Giant Biogene, are achieving increasing research breakthroughs and scientifically validated experimental evidence.

Approximately 70% of human skin consists of collagen, among which Type I and Type III collagen are particularly vital for maintaining skin firmness and elasticity. At the exhibition, Giant Biogene showcased its flagship Collgene products, all specially formulated with its proprietary C5HA Recombinant Collagen Biomimetic Complex. This complex comprises Mini low-molecular-weight recombinant collagen peptides, recombinant Type III collagen, and HLC patented recombinant collagen.^[2], Recombinant Type I Collagen, with excellent anti-wrinkle and firming effects.

Giant Biogene previously utilized a two-photon 3D dynamic model to visualize the skin penetration structure of its C5HA recombinant collagen raw material. Authoritative data effectively demonstrated the excellent transdermal absorption properties of this recombinant collagen, providing more intuitive and scientific evidence that it promotes endogenous collagen production in the human body.("Two-photon microscopy imaging technology" was successfully deployed aboard the Shenzhou-15 spacecraft in 2023, marking the world’s first known instance of acquiring three-dimensional images of astronauts’ epidermal and superficial dermal skin layers using a two-photon microscope during spaceflight. The three-dimensional structures of the stratum corneum, stratum granulosum, stratum spinosum, basal cell layer, and superficial dermis of the astronauts’ skin were clearly distinguishable.)^[3]。）

Scientifically validated and effective anti-aging solutions serve as a key benchmark tested by the market. As technology advances in the beauty and wellness industry and consumer perceptions evolve, upstream companies must consider how to expand their product portfolios while maintaining their competitive advantages. Today, traditional medical aesthetics firms, pharmaceutical companies, and beauty enterprises are increasingly entering the medical aesthetics sector, aiming to secure a strategic first-mover advantage amid the current surge in demand. Giant Biogene, a company dedicated to the life sciences sector with the mission of achieving public “beauty and health” goals through “biotechnology,” has long established its presence in the medical aesthetics landscape. At this year’s AMWC Congress, the company showcased Collgene Starlight, a product featuring its proprietary recombinant collagen ingredient. Having been on the market for six years, it has garnered favorable consumer feedback.

At the Giant Biogene satellite symposium held during this year’s AMWC, Dr. Liu Gang, Chief Physician and Level-1 Expert at Sichuan Provincial People’s Hospital, served as the chair and presided over the session. Dr. Wang Xi, Associate Chief Physician of Dermatology and holder of an M.D. from West China Hospital of Sichuan University, presented “New Explorations in Facial Rejuvenation with Recombinant Collagen: Clinical Applications of Comfy Star.” Dr. Feng Yanyan, Chief Physician of Dermatology and Associate Professor at Chengdu Second People’s Hospital, shared insights on “Clinical Applications of Recombinant Collagen: A Multidimensional Therapeutic Partner in Dermatology.” These presentations by frontline clinicians highlight the significant breakthroughs and future potential of recombinant collagen in dermatology and even the broader field of life sciences.

With the widespread application of recombinant collagen and the accumulation of an increasing number of clinical cases, it is believed that the industry and the public will gain a more comprehensive and profound understanding of this material. Zhang Shasha, Director of the Central Marketing Department at Giant Biogene, stated in an on-site media interview at the conference, “Giant Biogene has extensive future plans for category expansion and product portfolio development in the anti-aging sector, which are being actively advanced.”

The Chinese collagen market is experiencing rapid growth, with recombinant collagen expanding at a faster pace than animal-derived collagen. According to data from Frost & Sullivan, the market size of recombinant collagen products in China is projected to reach RMB 108.3 billion by 2027, indicating substantial market potential.

It is reported that, as of June 2024, Giant Biogene held 133 patents and patent applications. As the company continues to pursue higher-level, deeper, and broader technological exploration in recombinant collagen, it is expected to launch more products that will tangibly improve consumers’ lives. Looking ahead, amid the flourishing development of the recombinant collagen market, Giant Biogene is poised to advance steadily with greater determination, leveraging its leading scientific research expertise and keen market insight to drive progress in the anti-aging sector.

[1] "Colligen Film Cream," "Colligen Film Eye Cream," "Colligen Plumping Single-Dose Ampoule," and "Colligen Collagen Mega Mask" are product nicknames. The full product names are, respectively: Colligen Recombinant Collagen Revitalizing Lifting, Firming, and Anti-Wrinkle Essence Cream; Colligen Recombinant Collagen Revitalizing 3D Firming and Wrinkle-Reducing Essence Eye Cream; Colligen Human-like Recombinant Collagen Empowering Precious Firming and Elastic Single-Dose Essence; and Colligen Human-like Collagen Empowering Precious Firming and Age-Defying Mask.

[2] Chinese invention patent, ZL201110327873.X

[3] Sourced from the Xinhua News Network article published on February 27, 2023, titled “China’s Independently Developed Two-Photon Microscope on Space Station Captures First 3D Images of Astronauts’ Skin”