Knowledge Matrix Secures Tens of Millions in Series A+ Funding to Accelerate Innovation in the Health Industry with 'Content + Big Data' Dual Engines

VCBeat has learned that KNOTRIX has recently completed an A+ round (A2 round) of financing exceeding RMB 10 million. The lead investor was Mr. Chen Yongchao, Chairman of Huayu Venture Capital and a renowned investor, with Huayi Capital and Guangzhou Jiushiji as co-investors. This funding will further advance KNOTRIX’s content ecosystem development and commercial strategic layout in the big health sector.

All investors in this round have expressed strong confidence in the broader healthcare sector and the KNOTRIX project. Mr. Chen Yongchao, Chairman of Huayu Venture Capital and a renowned investor, stated, “KNOTRIX has the capability to help partners achieve significant business growth and injects new vitality into the industry. I believe its core competencies in content ecosystem development and data-driven decision-making will unlock greater potential in both domestic and international healthcare markets.” With over three decades of practical investment experience across primary and secondary markets, Mr. Chen is a venture capitalist acclaimed as the “God of Stocks in Jiangnan” and “the most passionate and visionary angel investor in hard technology.”

The Huayi Capital team, which specializes in quantitative investment in China’s primary healthcare and wellness market, stated: “KNOTRIX’s full-chain service system, spanning from IP incubation to product development, demonstrates exceptional market acumen and expansion capabilities. We are optimistic about KNOTRIX’s strategic layout in the healthcare and wellness sector and look forward to its continued leadership in driving industry progress and creating long-term value for investors.” It is reported that Huayi Capital has currently filed nine funds with a total assets under management (AUM) of nearly RMB 8 billion. As the definer of China’s comprehensive healthcare investment landscape, it operates the Huayi Research Institute, the only medical investment research institute in China. Yiyun Technology serves as Huayi’s post-investment management platform, dedicated to profiling and evaluating domestic healthcare and wellness enterprises using quantitative models.

Guangzhou Jiushiji, a company dedicated to “Lifestyle Medicine,” evaluates KNOTRIX from the perspectives of ecological integration and strategic layout: “In the rapidly evolving general health market, KNOTRIX has achieved remarkable success in content innovation, brand collaboration, and technology empowerment. Particularly in integrating resources and building a comprehensive ecosystem, it has demonstrated forward-looking strategic vision and strong execution capabilities.” Adhering to the philosophy of “integrating medicine into daily life and branding health,” Guangzhou Jiushiji supports the prevention, reversal, and rehabilitation of chronic diseases through an operational closed loop of “content–brand–product–cultural tourism,” while advocating and promoting healthy lifestyles and culture.

With the in-depth implementation of the “Healthy China 2030” Planning Outline, the big health industry has been infused with unprecedented vitality, and its market size continues to expand. Established in 2020, KNOTRIX specializes in six core business areas: precision marketing for medical and big health content, development of blockbuster IP for medical specialties, high-growth live streaming targeting precise audiences, joint operations for health brands/products, private-domain customization for health-sensitive customer segments, and big data support for commercial strategic decision-making. It provides efficient growth solutions for pharmaceutical companies, medical device enterprises, health consumer goods companies, and big health organizations.

Over the past four years, KNOTRIX has achieved a rapid leap from its inception to scaled development, establishing four major bases: its Hangzhou headquarters, and subsidiaries in Guangzhou, Chengdu, and Hong Kong. It has gradually formed a nationwide content operation ecosystem for the general health industry. To date, the company has incubated and collaborated with over 3,000 health-related IPs, accumulating a fan base of more than 430 million. It has partnered with over 1,000 brands, driving a cumulative GMV growth of more than RMB 500 million for its partners.

Facing the rapidly growing market of the broader health industry, KNOTRIX maintains keen insights at all times, closely integrating its own advantages with industry trends to actively expand its business development models. This May, Douyin partially opened live streaming for Class II medical devices. In its debut live stream for Class II medical devices on Douyin, KNOTRIX’s self-incubated leading women’s health IP, @XiaoWang Rehabilitation, achieved a single-day GMV exceeding RMB 7 million, repeatedly topping the category’s live streaming rankings. Leveraging strong content competitiveness and precise marketing strategies, KNOTRIX has comprehensively laid out online marketing for Class II medical devices, successfully helping partner brands rapidly break through in the content e-commerce sector. To date, KNOTRIX has established deep strategic collaborations with several global leading medical device brands, secured exclusive multi-platform operational authorizations from these brands, and is gradually building category-specific live streaming bases.

Meanwhile, KNOTRIX continues to ramp up its self-operated brand business. Its proprietary brands, including the children’s nutritional supplement brand Yuanliban and the children’s personal care brand Dr. Dinosaur, are gradually establishing a closed-loop system encompassing product development, marketing promotion, and sales operations. Supported by years of experience in operating a comprehensive health content ecosystem and its proprietary commercial big data models, KNOTRIX’s self-operated brands are achieving refined growth across multiple dimensions, emerging as high-potential growth drivers for the company.

Figure: KNOTRIX's Big Data Support Model for Business Strategic Decision-Making

As a data operations platform for the content ecosystem spanning the entire health and wellness sector, KNOTRIX is boldly venturing into the specialized deep waters of the broader health industry, driving its digital transformation through a robust content ecosystem. Ding Zhaoliang (Danggui), Founder and CEO of KNOTRIX, stated, “This round of financing has injected strong momentum into KNOTRIX. Moving forward, the company will continue to center on content and leverage big data as its foundation. While achieving revenue targets from existing business operations, we will continuously innovate to create long-term, sustainable value growth.”