Aphranel Magic CC Needle Global Launch: Chinese Innovation Redefines Regenerative Aesthetics

On May 8, 2025, the global launch event for “Aphranel Youfalan Magic CC Injection” (calcium hydroxyapatite microspheres facial filler for injection), a high-end regenerative medical aesthetic product independently developed by Moyang Biotechnology, was grandly held at the World Meeting Room in Shanghai.

Themed “Disruption · Rebirth: A Tribute to the World,” the press conference featured an opening address by Mr. Ren Dawei, Deputy Director of the Shanghai Biomedical Science and Technology Industry Promotion Center. Government officials in attendance included Mr. Wu Changfei, Party Secretary of the Shanghai Minhang District Science and Technology Commission, and Mr. Li Wei, Deputy Director of the Shanghai Minhang District Economic Commission. Distinguished domestic and international plastic surgery experts participated in the event and delivered speeches, including Professor Qi Zuoliang, former President of the Plastic Surgery Hospital of the Chinese Academy of Medical Sciences (Beijing Badachu) and Group President of Badachu Hospital Management Company; Professor Cui Haiyan, Founding Director of the Department of Plastic and Aesthetic Surgery at Tongji Hospital Affiliated to Tongji University; Professor Luo Shengkang, Professor of Plastic Surgery at Guangdong Second Provincial General Hospital; Professor Chen Guangyu, former Director of the Injection Cosmetology Center at the Plastic Surgery Hospital of the Chinese Academy of Medical Sciences; Professor Li Ya, Professor and Doctoral Supervisor in the Stage Design Department of the Shanghai Theatre Academy; and Dr. Stefan Lipp, MD from Goethe University Frankfurt and Executive Director of the Ratingen Medical Aesthetics Center in Germany. Authoritative global experts in medical aesthetics, representatives from industry associations, and leaders across the industrial chain attended the event, jointly witnessing Chinese medical aesthetic innovations enter the high-end international market and ushering in a new chapter in the global field of regenerative materials.

Aphranel: China’s Independently Developed Premium Aesthetic Dermal FillerAphranel is a high-end aesthetic medical dermal filler independently developed by a Chinese enterprise. As the first injectable calcium hydroxyapatite (CaHA) microsphere facial filler in China to receive Class III medical device certification from the National Medical Products Administration (NMPA) for aesthetic indications (Approval No.: Guo Xie Zhu Zhun 20253130390), it has joined the ranks of globally leading regenerative injectable aesthetic brands, leveraging technological breakthroughs in the precise control of CaHA microsphere particle size, pore structure, and degradation rate.

Its core material, CaHA, utilizes the “raspberry-like macroporous structure” ACD-MT™ patented microsphere technology, combined with the PCD-ETT™ physically cross-linked gel system, resulting in biocompatibility that far exceeds international standards.

Currently, Aphranel Youfulan Magic CC Needle has obtained EU MD, MDSAP, and Mexico COFEPRIS certifications, becoming the first Chinese medical aesthetics regenerative material brand to simultaneously expand into the Asian, European, and Latin American markets.

At the gala, Mr. Lin Guangming, Founder and Chairman of Shanghai Moyang Biotechnology Co., Ltd., reviewed the ten-year journey of Youfalan from research and development to clinical application. Upholding the original aspiration of returning medical aesthetics to its medical essence, the scientific research team conducted product development with a rigorous scientific attitude. This process serves as a microcosm of China’s medical aesthetics industry transitioning from “following” to “keeping pace,” and now striving to become a global “leader.”

Many overseas medical experts have also stated that the globalization of Youfulan is not merely a commercial strategy, but also provides a “Chinese solution” for global medical aesthetics, featuring controllable degradation and precise anti-aging.

(From left to right in the photo: Dr. Stefan Lipp, M.D., Executive Director of the Laettingen Medical Aesthetics Center, Germany; Professor Luo Shengkang, Director of the Department of Plastic Surgery, Guangdong Second Provincial General Hospital; Professor Cui Haiyan, Founding Director of the Department of Plastic and Reconstructive Surgery, Tongji Hospital Affiliated to Tongji University; Professor Chen Guangyu, Former Director of the Injection Cosmetology Center, Plastic Surgery Hospital, Chinese Academy of Medical Sciences; Professor Qi Zuoliang, Former President of the Plastic Surgery Hospital, Chinese Academy of Medical Sciences (Beijing Badachu), and Group President of Badachu Hospital Management Company; Mr. Lin Guangming, Founder and Chairman of Shanghai Moyang Biotechnology Co., Ltd.; Mr. Ren Dawei, Deputy Director of the Shanghai Bio-medicine Industry Promotion Center; Mr. Li Wei, Deputy Director of the Economic Commission of Minhang District, Shanghai; Mr. Zhang Wei, General Manager of the Anesthesiology Center, Sinopharm Group Pharmaceutical Co., Ltd.; and Dr. Amr Youssef, Founder and President of the International Association for Dermatology and Cosmetic Medicine (USA).)

As the special ceremony of the gala commenced, a butterfly representing Youfulan took flight, symbolizing that Youfulan will drive a transformative innovation in the medical aesthetics industry and ignite a global aesthetic revolution. During the plaque-awarding ceremony, Youfulan presented cooperation certification plaques to the first batch of 68 strategic partner medical aesthetic institutions, in recognition of their trust in the Youfulan brand and their long-term support. This awarding marks the official launch of deep collaboration between both parties in the field of medical aesthetics, as they join hands to enhance the end-consumer experience.

This gala was specially presented in collaboration with the Shanghai Theatre Academy. Mr. Zhang Weiling, Vice President of the Shanghai Theatre Academy Alumni Association and Vice Chairman of its Education Development Foundation, and Mr. Zhang Wei, General Manager of the Anesthetic Center at Sinopharm Group Co., Ltd., delivered speeches at the event. The gala featured a diverse program spanning classical dance, ballet, musical theater, magic, and Peking opera-inspired songs, highlighted by a romantic jazz dance performance in the rain that harmonized perfectly with the ambiance. These romantic, diverse, and fashionable performances collectively created a multi-scene artistic atmosphere. The plurality of artistic forms mirrored the international layout of Youfalan’s product matrix, interpreting the brand philosophy of “Disruption · Rebirth” through cultural synesthesia. This established an aesthetic dialogue bridging East and West, allowing every guest to immerse themselves in the feast of metamorphic aesthetics advocated by Youfalan.

Centered on the theme “Returning Aesthetic Medicine to Its Medical Essence,” the world’s first roundtable forum on regenerative materials was held concurrently. Moderated by Mr. Xiaodong, founder of Jasmine Zhenxiang, the forum featured in-depth discussions among medical experts and industry professionals, including Mr. Lin Guangming, Founder and Chairman of Moyang Biotechnology; Professor Luo Shengkang, Director of the Department of Plastic Surgery at Guangdong Second Provincial General Hospital; Professor Cui Haiyan, Founding Director of the Department of Plastic and Reconstructive Surgery at Tongji Hospital Affiliated to Tongji University; Ms. Wang Xiaolu, Chairwoman of Shenzhen Sunshine Medical Beauty Group; Mr. Wang Binbin, CMO of Yuansong Group; and Ms. Jiang Zhongrong, Founder of Rongyue Medical. The panelists engaged in profound dialogue from multiple perspectives, including medicine, aesthetics, global strategy, and industry significance, reaching a consensus that Youfulan’s Oriental Metamorphosis Aesthetics will drive the iteration of personalized anti-aging solutions toward greater precision, longevity, and safety, thereby reshaping the value standards of the global aesthetic medicine ecosystem.

Currently, Shanghai Moyang Biotechnology Co., Ltd. has joined forces with institutions such as the Shanghai Theatre Academy to initiate the conceptual development of an Oriental Aesthetic Art Space. Through multi-party collaboration, the company aims to establish Chinese-style transformative aesthetics as a new global paradigm in anti-aging.

“The launch of Youfalan demonstrates that China’s intelligent manufacturing can take its place on the global stage with the rigor expected in the medical field,” said Lin Guangming, Chairman of Shanghai Moyang Biotechnology Co., Ltd. “We look to Youfalan as a starting point to drive compliance across the global medical aesthetics industry, bringing safe, natural Chinese aesthetic concepts to more consumers.”

Aphranel, a high-end injectable calcium hydroxyapatite (CaHA) microsphere facial filler independently developed in China, has obtained the EU MD and MDSAP certificates, product registration approval from Mexico’s COFEPRIS, and Class III medical device registration certification for aesthetic medical indications approved by China’s NMPA. Aphranel’s proprietary “Magic CC Needle” features an innovative dual synergistic mechanism of “support + regeneration.” Its ACD-MT™ patented microspheres enable controlled degradation, while the physical cross-linking method of its PCD-ETT™ patented gel avoids the health risks associated with residual chemical cross-linking agents. Clinical and multi-center studies have verified that the product fully degrades within the human body over 12–15 months without any residue, allowing for precise contouring and natural, three-dimensional bone structure enhancement. It is hailed by the industry as “the new benchmark in regenerative aesthetics.”

Moyang Biotechnology is a representative of China’s high-end medical aesthetics brands and a national high-tech enterprise dedicated to the research and development, production, sales, and consulting services of nano-medical biomaterials and Class III absorbable implants. Guided by the core philosophy of “Medicine as the Foundation, Aesthetics as the Wings,” the company has established an innovative system encompassing materials science, clinical medicine, and skeletal aesthetics. Adhering to innovation-driven product applications, Moyang Biotechnology provides rigorous and professional services to physicians and aesthetic seekers, striving relentlessly to become a core representative of “New Chinese Intelligent Manufacturing” in the field of reconstructive surgery in China.