Chengdu Kerui Science And Technology Co., Ltd. (hereinafter referred to as “Kerui Tech”), a leading domestic enterprise in the field of ultra-high performance liquid chromatography (UHPLC), has recently completed a Pre-B financing round worth tens of millions of yuan. This round of financing was invested by Sichuan Development Hongke Fund. The injection of capital will accelerate Kerui Tech’s efforts to refine its UHPLC product line, expand market promotion, and improve and promote automated chromatography-mass spectrometry laboratory application solutions.

Chengdu Kerui Science And Technology Co., Ltd., established in 2016, is a leading analytical instrument manufacturer dedicated to the research and development of intelligent ultra-high-performance liquid chromatography (UHPLC) systems, networked instrument analysis software, and high-value-added core components. Currently, the domestic substitution of scientific instruments has been elevated to a national strategy, with the 14th Five-Year Plan explicitly supporting independent innovation in high-end scientific instruments. However, due to factors such as multidisciplinary integration, high industry barriers, bottlenecks in user trust, difficulties in reaching users, and inefficient capital matching, the scientific instrument industry requires long-term investment and exhibits the characteristics of a “long slope with thick snow.” Consequently, domestic instrument manufacturers face significant challenges.Kerui Technology remains committed to long-term R&D investment, with cumulative R&D expenditures exceeding RMB 80 million. Adhering to the principle of “doing what is difficult yet right,” the company has successfully overcome critical bottlenecks in core components, achieving fully independent R&D and domestic production of these key parts.Breakthroughs in the independent R&D and localization of core components have enabledSignificant Reduction in BOM Costs for Kerui Tech ProductsAt the same time, it remains unconcerned about the increased uncertainty stemming from the volatile international landscape, having established a domestic manufacturing supply chain for analytical instruments that is sufficiently “self-sufficient.” While the high-end liquid chromatography market is dominated by four leading overseas companies holding over 90% of the market share,Kerui Tech’s ultra-high performance liquid chromatography (UHPLC) product series has completed sales and delivery of hundreds of units, positioning it as a leader among domestic brands.; it is one of the few domestic liquid chromatography manufacturers to have simultaneously entered high-standard systems such as Customs, Food and Drug Inspection, Centers for Disease Control and Prevention, and Judicial Authorities.

Scientific instruments are characterized by a large market, highly segmented product categories, and diverse niche sectors. Leveraging its own strengths, Kerui Technology has focused on cultivating certain “small but beautiful” niche segments. For instance, in the niche sector of wastewater-based drug testing, Kerui Technology’s flagship product is the Pisces series “Online Solid-Phase Extraction Two-Dimensional Liquid Chromatography System.”Widely recognized and chosen by over 30 public security agencies and third-party forensic testing clients, with an annual sample testing volume exceeding 50,000 cases.; The product’s performance has also been validated in the National Public Security Anti-Drug Department’s Drug Analysis Skills Competition. Furthermore, Chengdu Kerui Science And Technology Co., Ltd. continues to optimize and achieve breakthroughs in specialized application areas such as gel permeation chromatography (GPC) and ultra-high-performance liquid chromatography for fingerprint analysis of traditional Chinese medicine formula granules.A joint Gel Permeation Chromatography (GPC) laboratory has been established with Qingdao University of Science and Technology to develop more application solutions and analytical standards based on domestically produced GPC systems, thereby deepening exchange and cooperation in this field.

Application of the Pisces Series Online Solid-Phase Extraction Two-Dimensional Liquid Chromatography-Mass Spectrometry System in the Detection of Water Pollutants
Guided by the long-term goal of domestic substitution, Kerui Technology adheres to a market-demand-oriented approach, aiming to “address the pain points experienced by users of analytical instrument products.” The company has gained market recognition for its intelligent and automated solutions for sample preparation, separation, and detection. Kerui Technology will continue to expand into new fields and build a product portfolio in the realm of intelligent and automated analysis. The fully automated sample pre-treatment platform currently under development will truly realize “Sample to Answer,” achieving end-to-end laboratory analysis automation from sample to result, thereby making laboratory testing more efficient, accurate, and reliable.
Bolstered by this round of financing, Chengdu Kerui Science And Technology Co., Ltd. will continue to leverage its leading R&D team and technology development platform in China’s ultra-high-performance liquid chromatography (UHPLC) industry to actively expand its innovative product portfolio, empowering a broader range of scientific research and industrial applications. As we advance the critical initiative of domesticating scientific instruments, we are confident that further capital support is on the horizon.
Sichuan Development Hongke Fund investor Pu Wencheng statedAs a high-end precision analytical instrument, liquid chromatography is widely used in fields such as biopharmaceuticals, environmental monitoring, food safety, and industrial analysis. As a leading domestic R&D and manufacturer of liquid chromatography systems, Chengdu Kerui Science And Technology Co., Ltd. has established significant technical barriers by achieving breakthroughs in the development of core components. Its ultra-high-performance liquid chromatography (UHPLC) products have achieved mass sales, breaking the monopoly of high-end imported brands and demonstrating substantial market potential. We hope the company will achieve further breakthroughs in the future and become a top-tier industry leader.
Sichuan Development Hongke Fund was established in 2017. It is a member enterprise of Sichuan Development Group and a wholly-owned subsidiary of Sichuan Biomedical Industry Group Co., Ltd. Sichuan Biomedical Group focuses on investment and operation in the biomedical industry. Through key measures such as industrial integration, collaboration with leading enterprises, synergy of production factors, and fund investment, it is committed to cultivating and building leading and pillar industries in the biomedical sector. It aims to guide and drive the aggregation of advantageous resources related to the industry in Sichuan, promoting the high-quality development of Sichuan’s biomedical industry. Hongke Fund currently manages two funds, with assets under management totaling nearly RMB 1 billion. Since its establishment, it has focused on venture capital investment in the technology sector, selecting high-quality projects, promoting the transformation of scientific and technological achievements, and nurturing a group of industry-leading enterprises.