Shanghai Ninth People's Hospital Affiliated to SJTU School of Medicine Licenses Postoperative Ocular Care Technology for RMB 150,000
Recently, Shanghai Ninth People’s Hospital, affiliated with Shanghai Jiao Tong University School of Medicine, released a public notice on the proposed conversion of its scientific and technological achievements. The hospital intends to transfer these achievements through listed trading via the Shanghai Technology Exchange.“A Postoperative Ocular Dressing and a Postoperative Full-Eye Dressing”The utility model patent has been transferred to Shanghai Yabaiyan Medical Technology Co., Ltd., with an agreed transfer amount of RMBRMB 150,000。
The inventor of this patented technology isZeng Changjuan, Li Jin. The team focuses on the field of postoperative ocular care and, in response to actual clinical needs, has innovatively designed a specialized dressing for use after eye surgery. This innovation aims to enhance patient comfort and safety during postoperative recovery and demonstrates clear clinical application value.
Zeng Changjuan:Currently serves as the Head Nurse of the Department of Ophthalmology at Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, and as a Master’s thesis supervisor. Has long been engaged in clinical practice and research involving pediatric patients and their caregivers, with extensive experience in the management of retinoblastoma and support for caregivers, and is well-versed in frontier research advancements in this field. Has presided over 17 projects as the principal investigator, including those funded by the Shanghai Shenkang Hospital Development Center, the Nursing Highland Discipline Construction Project of the Shanghai Municipal Education Commission, and the Shanghai Nursing Association. Has published 25 papers as the first or corresponding author (including 10 SCI-indexed papers), holds 12 authorized patents (including 3 invention patents), has published 5 popular science articles, and has contributed to three monographs. Has been honored withSecond Prize of the “Nursing Science and Technology Award” under the Chinese Nursing Association Science and Technology Awards; Second Prize of the Shanghai Science and Technology Popularization Award; Second Prize of the Nursing Science and Technology Award of the Shanghai Nursing Association; Outstanding Correspondent of the Chinese Journal of Nursing; Medical Social Contribution Award at the Healthy China Sinan Summit, and has received multiple awards in academic papers and nursing innovation project exchanges.
Li Jin:Chief Physician, Doctoral Supervisor, and Deputy Director of the Department of Ophthalmology Teaching and Research Section at Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine; Member of the Cornea Disease Group of the Shanghai Medical Association. He graduated from the English-track Clinical Medicine Program at Shanghai Second Medical University in 1995, received his Master’s degree in Ophthalmology from the same university in 2003, and earned his Ph.D. in Ophthalmology from Shanghai Jiao Tong University School of Medicine in 2006 under the supervision of Professor Fan Xianqun, a renowned expert in oculoplastic surgery. In 2009, he served as a visiting scholar at the University of South Alabama, USA, and in 2012, he completed advanced training in corneal diseases at Beijing Tongren Hospital. He has held positions including Resident Physician, Attending Physician, and Associate Chief Physician, and was promoted to Chief Physician in 2014. His clinical expertise includes the diagnosis and treatment of ocular surface diseases (such as dry eye syndrome and pterygium), corneal transplantation, and plastic surgeries such as eyelid tumor resection and double eyelid formation. He has extensive experience in managing pediatric orbital–facial clefts, dermoid tumors, chemical injuries of the ocular surface, and symblepharon. He has presided over three projects funded by the National Natural Science Foundation of China and published eight SCI-indexed papers.Recipient of the First Prize of the Shanghai Science and Technology Progress Award, the Second Prize of the Ministry of Education Science and Technology Progress Award, and selected for the “Hundred Talents Program” of Shanghai Jiao Tong University School of Medicine.
Assignee of this Patent TechnologyShanghai Yabaiyan Medical Technology Co., Ltd., dedicated to the development and application of medical devices and related technologies, this acquisition of the patented technology for post-operative eye dressings aims to further expand its product portfolio and technological reserves in the field of ophthalmic care.
The patent achievement proposed for commercialization in this instance is a medical dressing specifically designed for postoperative eye care.Its core function is to cover and protect the ocular region postoperatively, absorbing exudate through an integrated absorbent layer while alleviating patient discomfort via a ring-shaped cooling component. The dressing features an all-in-one design; application simply requires peeling off the release liner and aligning it for adhesion. This allows for rapid, single-person application, streamlining nursing workflows and enhancing both operational efficiency and patient experience.
This patent primarily targetsWound care needs following various types of ophthalmic surgery.For instance, procedures such as cataract extraction, glaucoma filtration surgery, blepharoplasty, corneal transplantation, and retinal reattachment all create surgical wounds of varying sizes in the eye. In the early postoperative period, there may be exudation of tissue fluid, small amounts of blood, or medicinal solutions from the wound site, and the eye itself may produce tears in response to irritation.
Currently, the postoperative dressing protocol widely adopted in clinical practice involves the use of sterile gauze combined with medical adhesive tape. The specific procedure entails placing a folded square piece of gauze directly over the closed eyelid. One healthcare professional manually holds the gauze in place, while another applies multiple strips of medical adhesive tape to secure the edges of the gauze to the skin surrounding the patient’s orbital region. Medical adhesive tape is typically a strip composed of a fabric or non-woven base material coated with pressure-sensitive medical-grade adhesive.
This traditional method firstIn terms of operational proceduresSignificant drawbacks exist. It requires the coordinated effort of two healthcare professionals: one to perform compressions and the other to apply electrodes. This directly results in a waste of human resources, increases the time cost and coordination burden for nursing staff in busy clinical settings, and reduces work efficiency.
Secondly,In clinical use,This approach has exposed more problems. In pediatric patients who cry due to postoperative pain and fear, tear secretion increases significantly. The main components of tears are water, salts, proteins, and lipids. When these components heavily saturate the gauze, the water causes the gauze fibers to swell, while organic substances such as proteins exhibit certain adhesiveness. This can lead to adhesion between the moistened gauze and the eyelid skin, or even with the surgical wound area that has not yet fully closed.
During dressing changeForcibly removing gauze that has become hardened after drying or adhered to the wound surface can easily cause secondary mechanical injury to the delicate periocular skin, and may pull on unhealed wounds, resulting in pain, bleeding, and disruption of the healing process.
On the other hand, for patients with large surgical wounds and significant exudation of blood and fluids, ordinary gauze has limited absorbent capacity, and the absorbed fluid tends to spread outward. This often leads to rapid saturation of the gauze, with the inner layer in contact with the wound becoming soaked in blood and tissue fluid, while the outer layer may also become dampened.
Moist gauze saturated with protein and blood creates a warm culture medium that is highly conducive to the growth and proliferation of bacteria from the environment or skin surface, such as *Staphylococcus aureus* and *Staphylococcus epidermidis*. If not changed in a timely manner, these bacteria may multiply extensively and migrate to the wound, causing postoperative infection, which can severely compromise surgical outcomes and even lead to serious complications such as endophthalmitis.
Furthermore, during hot seasons or in high-ambient-temperature environments, covering the closed eyelids with multiple layers of gauze can severely impede local sweat evaporation and heat dissipation. This creates a sealed, humid, and high-temperature microenvironment around the eyes. Such stuffy conditions not only cause significant discomfort and a sensation of pressure for patients but may also induce skin problems such as folliculitis and contact dermatitis due to prolonged exposure of the local skin to heat and moisture. Meanwhile, the warm and humid environment itself accelerates microbial proliferation, further increasing the risk of infection.
FaceRegarding the aforementioned clinicalThe Multiple Dilemmas in Nursing Care Urgently Call for an Innovative Dressing Design That Fundamentally Optimizes Operational Processes and Enhances Patient Experience. This Requires That New Dressings Not Only Integrate Functions and Simplify Procedures, But Also Achieve Breakthroughs in Materials Science and Structural Design to Simultaneously Meet Core Clinical Needs Such as Efficient Absorption, Prevention of Adhesion, Maintenance of Comfort, and Reduction of Infection Risk.
This achievement provides aHighly Integrated Structurepostoperative eye dressing. Its core advancements are primarily reflected inThorough Simplification of Operational Procedures.This patch features a pre-integrated functional design: the base sheet is directly divided into an ocular coverage area for covering the eyelids, and an eye patch fixation component that extends outward and incorporates an adhesive layer.
Most critically, the areas requiring adhesion and those covering the absorbent layer are protected by a unified primary release liner assembly. This assembly, typically made of release paper, simultaneously covers both the adhesive layer of the fixation component and the dry exudate-absorbing pad at the center of the dressing.
Therefore,In clinical use,Healthcare personnel need only peel off the entire isolation paper in one go to simultaneously expose both the adhesive layer and the central area of the dressing, allowing a single operator to complete the entire process of alignment, application, and press-to-fix. This fundamentally eliminates the two-person collaboration required by traditional methods, simplifying the procedure into a standardized, one-step action that significantly saves time and labor.
In enhancing nursing safety and promoting healing,This dressing addresses the challenge of exudate management through a multi-layered composite structure. Its absorbent component features a layered design: the inner layer, which is in direct contact with the eye, is a high-efficiency absorbent layer composed of wood pulp cotton and superabsorbent polymer.
Superabsorbent polymers are functional polymers with a network structure that can absorb and retain hundreds of times their own weight in water, converting liquids into a gel-like state. This significantly enhances absorption capacity and fluid-locking ability per unit area, effectively managing substantial postoperative bleeding and exudate.
On the outer side of the absorbent layer, i.e., the side away from the skin, there is a dry fluid-permeable layer, typically made of specially treated non-woven fabric. The key function of this layer is to“Permeable but Non-Reinfiltrating”, it allows internal water vapor to permeate through, maintaining a certain level of breathability, while preventing the absorbed liquid from penetrating back to the outer layer.
This keeps the outer layer of the dressing consistently relatively dry, thereby avoiding the problem associated with traditional gauze becoming a breeding ground for bacteria when saturated with fluids from both inside and outside. Meanwhile, the dry outer surface is less prone to adsorbing external contaminants, and many medical non-woven fabrics possess inherent bacteriostatic and antibacterial properties; these factors work synergistically to reduce the risk of wound infection.
For Children Crying Postoperatively, this design enables rapid absorption of tear fluid while keeping the outer layer dry, effectively preventing wet gauze from adhering to the skin or wound and thereby avoiding secondary injury caused by adhesion during dressing changes.
In terms of improving patients' subjective comfort,This patent innovatively introduces an active cooling module. A cooling element is arranged in a ring shape along the edge area of the water-absorption layer, which consists of a cooling carrier (such as specific fibers or a gel matrix) and cooling agents loaded thereon (such as safe ingredients like menthol).
Once the patch adheres to the periocular skin, body heat facilitates the gradual volatilization of cooling agents, generating a sustained, mild cooling sensation around the eyes. This physically induced cooling effect offers multiple benefits.
First, it can directly counteract the stuffiness caused by dressing coverage in hot environments, thereby enhancing physical comfort.
Secondly, the sensation of coolness, as a mild physical stimulus, can help divert patients’ attention from postoperative pain to some extent, thereby providing an adjunctive soothing effect.
Thirdly, moderate local hypothermia helps induce mild constriction of capillaries, which may have a certain auxiliary effect in reducing tissue swelling.
Furthermore, this utility model also takes into account more comprehensive clinical scenarios, deriving through modular design"Postoperative Full-Eye Dressing" Model. This model essentially consists of two independent eye patch units connected in the middle by a flexible eye patch connector. This connector also features a removable release liner.
This design is specifically tailored to provide convenience for patients requiring simultaneous coverage of both eyes, such as in cases following certain ophthalmic surgeries or during light-avoidance rest periods. During application, healthcare professionals can remove all isolation components from the connectors and the two dressing units in a single step, similar to using a large patch, and then accurately and synchronously cover and secure both eyes.
This ensures that the convenience of single-operator use is maintained even in binocular coverage scenarios, while guaranteeing consistency and efficiency in left and right eye care.
Currently, the global market for post-operative ophthalmic care is rapidly evolving toward greater convenience, intelligence, and comfort. In response to this substantial demand, not only does this technology offer innovative solutions, but numerous medical device companies both in China and abroad are also continuously advancing their R&D strategies in this field, aiming to enhance product competitiveness through diverse technological approaches.
in the international market，Cellution Biologics Inc.is a company focused on providing advanced human tissue products, dedicated to advancing medical fields, including ocular wound care, through human tissue-based solutions.
In terms of postoperative eye care,The company recently announced the launch of two new products in the United States:AmnioPlast 1™ (Dehydrated Single-Layer Human Amniotic Membrane Allograft) and AmnioPlast Double™ (Dehydrated Double-Layer Amniotic Membrane Allograft). These two products are specifically designed for ocular surface repair, serving as a protective barrier on the ocular surface following reconstructive or reparative surgeries for ocular diseases or abnormalities. The products undergo sterile processing to preserve the natural structure of the amniotic membrane and are supplied as ready-to-use membranes that do not require frozen storage, offering a convenient and consistently reliable option for clinical and operating room environments.
Currently, these two products were officially launched in the United States on November 19, 2025.
In China,Sinopharm Dongfeng Maojian HospitalFocusing on the field of ocular protection for patients during general anesthesia surgery.
To address the risks of ocular dryness and corneal exposure in patients undergoing general anesthesia due to the effects of anesthetic agents and surgical positioning, as well as the limitations of traditional eye protection methods in terms of operational convenience and comfort, the operating room team at this hospital has innovatively introduced an eye protection technique using “sterile neurosurgical cotton patties + sterile dressings,” specifically as follows:“Moistened sterile cotton pledgets + sterile film eye patches”combination regimen.
This achievement has been implemented in clinical nursing innovation. With advantages such as better fit of brain cotton patties to the eye area, superior moisture control, and convenient and cost-effective operation, this technique has been clinically proven to effectively reduce postoperative discomforts like photophobia and tearing, lower the incidence of exposure keratitis, and provide a new reference for standardized intraoperative eye care in operating rooms. The hospital will continue to optimize this intraoperative eye protection protocol and promote the technology.
Guangdong Jingwei Biotechnology Co., Ltd.Mengdafu®, an innovative brand under the company, focuses on the field of mucosal repair and drives the R&D and innovation of high-end medical devices through a dual-core strategy of “regenerative medicine + synthetic biology.”
In the field of postoperative eye care,Meng Dafu® has launched a product based on wet therapy technology for dry eye diseaseShimeiqing®Among its related achievements, the medically formulated moist eye patch it developed has pioneered a new moist therapy regimen for dry eye symptoms. This innovation stands as one of the brand’s four milestone achievements in realizing import substitution and has been featured as a core exhibit in external showcases.
Overall, the aforementioned companies and products demonstrate diverse development trajectories in the fields of post-ophthalmic surgery care and ocular surface repair, ranging from high-end biomaterial transplantation to convenient functional dressings, thereby collectively addressing differentiated clinical needs. Technological exploration and product development in this sector continue to advance, aiming to meet patients’ pursuit of superior therapeutic efficacy and enhanced comfort.