Recently, Beijing Luhe Hospital Affiliated to Capital Medical University released a public notice on the conversion of its scientific and technological achievements, proposing to transfer its“A Micro-Trephine Device for Miniature Skin Grafting”Patent assignment to Beijing Junzhitai Medical Device Co., Ltd., with a transaction amount of50,000 yuan。

Image from the official website of Beijing Luhe Hospital, Capital Medical University
This miniature skin graft harvesting device with a micro-trephine consists ofWang Huiying, Fu Xiaoxiao, Zhao Huanjun, and Bian Chenghao from the Department of BurnsDeveloped as a utility model patent, this innovation addresses the limitations of traditional micro-skin harvesting and grafting—namely, its time-consuming nature, labor intensity, and high technical demands. It is suitable for minimally invasive treatment of hard-to-heal wounds, such as pressure ulcers and diabetic foot ulcers.
Against the backdrop of an aging population and the continuous development of transportation tools,Refractory Wounds, Including Pressure Ulcers, Diabetic Foot Ulcers, Ischemic Ulcers, and Post-Traumatic Ulcers...the clinical incidence has risen significantly, becoming a major clinical challenge in the current medical field.
For this type of wound, routine practice canSurgical closure using pedicled flap transfer, large-sheet skin grafting, or full-thickness skin grafting.. However, a large number of patients with poor baseline conditions in clinical practice cannot tolerate general anesthesia, spinal anesthesia, or highly invasive surgeries due to organ dysfunction. Additionally, some patients and their families refuse such high-trauma procedures, leaving them reliant on conservative treatments such as dressing changes, negative pressure wound therapy, and platelet-rich plasma. This not only results in slow wound healing but also allows chronic non-healing wounds to deteriorate the patient’s overall condition, causing significant physical and psychological distress to both patients and their families, while imposing a heavy burden on society and households.
Minimally Invasive Micro Full-Thickness Skin Graft Embedding TechniqueThis approach provides an effective treatment regimen for such patients, and clinical evidence has confirmed that the dermal tissue formed at the wound site by this technique can expand synchronously, exhibiting superior abrasion resistance and elasticity compared to healing achieved through epithelial migration from the wound edges.However, the traditional operational procedures for micro-punch skin harvesting and grafting have significant drawbacks:Skin harvesting requires obtaining skin grafts with a scalpel under local anesthesia, followed by mincing them into micro full-thickness skin particles. For planting, the recipient site must be disinfected and anesthetized, after which punctures are made using syringe needles for implantation. This entire procedure is time-consuming and labor-intensive, demanding exceptionally high technical proficiency from the operator. Moreover, the operator’s skill level directly impacts the survival rate of the micro-skin grafts, preventing the establishment of standardized, protocol-driven clinical procedures. Consequently, efficient clinical promotion and application are challenging, thereby limiting the widespread adoption of minimally invasive micro full-thickness skin embedding technology.
Therefore, there is an urgent need for a specialized instrument compatible with minimally invasive micro full-thickness skin graft embedding technology. Through equipment innovation, this device aims to address the multiple pain points of traditional procedures, thereby enabling standardized and streamlined clinical application of this high-quality minimally invasive treatment technique.
This micro-ring trephine device for miniature skin grafting addresses the pain points of traditional procedures through targeted technological innovations, creating an integrated and standardized minimally invasive skin grafting system. Its core innovations are reflected in the dual optimization of structural design and functional adaptability.
AtStructural DesignAspect,The device adopts a modular combination design.. The trephine gun handle and the micro-drill bit are assembled in a detachable manner via threaded connections. The micro-drill bit is integrally formed from a hollow shroud, trephine bits, and a connector. Multiple trephine bits are evenly distributed in a matrix pattern on the left side of the hollow shroud, overcoming the limitations of traditional single-point operation and enabling simultaneous multi-point operation, which significantly improves the efficiency of skin harvesting and grafting procedures.
InFunctional ConfigurationAbove,The device innovatively integrates a dual-purpose positive/negative pressure air pump, an air guide hose, and an air pump controller.. The air pump is connected to the handle of the trephine gun via an air-conducting hose, allowing flexible regulation of positive and negative pressure through the air pump controller. It enables precise adsorption and extraction of microskin grafts using negative pressure, while also assisting in the implantation of microskin grafts using positive pressure. This replaces manual operations such as cutting with a traditional scalpel and creating incisions with syringe needles, thereby standardizing the process of harvesting and planting microskin grafts.
Meanwhile, the integrated equipment design consolidates the core procedures of skin harvesting and grafting into a single device, eliminating the need for frequent instrument changes. This not only simplifies operational steps and lowers the technical requirements for operators but also enables standardized, process-oriented workflows for micro-skin grafting. By ensuring consistent spacing and operational stability at the equipment level, this approach ultimately improves the survival rate of micro-skin grafts.
Currently, there are no integrated specialized instruments on the market that fully match the functionality of micro-punch devices for harvesting and grafting micro-skin. Most comparable products are single-function devices designed solely for skin grafting, skin harvesting, or wound repair. A detailed analysis is provided below:
Kehuan Meizuan Microskin Grafting Special Drill, Developed by Jinan Kemei Technology, is currently the scar/skin graft-specific trephine instrument on the market that most closely resembles the patented product, newly launched in January 2026. This product features custom ultra-short drill bits for microskin grafting, enabling precise control of harvesting depth and retrieval of split-thickness skin grafts to meet minimally invasive harvesting requirements. Manufactured from medical-grade specialty stainless steel, it is available with drill bits in multiple specifications. However, this product consists solely of single-purpose skin-harvesting drill bit accessories and lacks seeding functionality; it must be used in conjunction with the brand’s proprietary trephine device.
Zimmer Biomet Electric DermatomeFor imported classic skin grafting instruments, byGuangzhou Huaxi Sci-Tech Innovation Co., Ltd.Agency sales. This product offers stable performance and can harvest skin grafts with neat edges and uniform thickness, making it suitable for harvesting large-sheet skin grafts in routine clinical skin transplantation surgeries. However, it only provides a single skin harvesting function, and its bulky size makes it unsuitable for the refined operational requirements of minimally invasive micro-skin grafting.