Capture the Fracture® Partnership Aims to Reduce Osteoporotic Hip and Vertebral Fractures by 25% by 2025
Amgen
Developer of Treatment Drugs for Serious Diseases
UCB
Biopharmaceutical and Specialty Chemicals Developer
International Osteoporosis Foundation
The International Osteoporosis Foundation is the world’s largest non-governmental organization dedicated to the prevention, diagnosis, and treatment of osteoporosis and related musculoskeletal diseases. Since its inception, the IOF has led the global osteoporosis movement, raising awareness of the disease among all stakeholders worldwide.
University of Oxford
The University of Oxford (commonly referred to as "Oxford") is a public research university located in Oxford, England. Operating under a collegiate federal system, it is collectively known with the University of Cambridge as "Oxbridge." Together with the University of Cambridge, University College London, Imperial College London, and the London School of Economics and Political Science, it forms the "G5 Super Elite Universities."While the exact founding date of the University of Oxford is lost to history, archival records clearly indicate that teaching commenced as early as 1096. The university experienced rapid development after receiving substantial support from the English royal family in 1167. It is the oldest university in the English-speaking world and the second-oldest surviving higher education institution globally. The University of Oxford holds prestigious academic standing and extensive influence in fields such as mathematics, physics, medicine, law, and business, and is widely recognized as one of the world’s leading higher education institutions. In the 2017–18 Times Higher Education World University Rankings, Oxford ranked first worldwide; in the Academic Ranking of World Universities (ARWU), it ranked seventh globally.On December 18, 2018, the "2018 World Brand 500" list, compiled by the World Brand Lab, was released, with the University of Oxford ranked 99th.
Nyon, Switzerland, June 16, 2020 /PRNewswire/ -- The International Osteoporosis Foundation (IOF) announced today a collaboration with the University of Oxford, Amgen, and UCB to support the Capture the Fracture® program. This initiative aims to reduce osteoporotic hip and vertebral fractures by 25% by 2025. Currently, more than 200 million people worldwide are estimated to suffer from osteoporosis,[4] resulting in an osteoporotic fracture every three seconds.[5]
Osteoporosis is a serious chronic disease that can cause bones to become fragile, porous, and more prone to fracture over time;[5] nevertheless, patients and healthcare providers can take a series of measures to reduce the risk of fractures.[1] The “Capture the Fracture” campaign, initiated by the International Osteoporosis Foundation (IOF) and supported by Amgen, UCB, and the University of Oxford, is a global initiative designed to help hospitals and healthcare systems proactively implement Post-Fracture Care (PFC) coordination programs, thereby helping patients prevent secondary fractures caused by osteoporosis. Currently, even after an osteoporotic fracture has occurred, approximately 80% of high-risk patients remain unidentified and untreated.[6]
“Osteoporosis is a global problem, causing nearly 8.9 million fractures annually,[3] and the risk of subsequent osteoporotic fractures increases by 86% after an initial fracture.[7] Strengthening post-fracture identification, diagnosis, and treatment for patients through early intervention can improve therapeutic outcomes and alleviate the burden on healthcare systems.[5]” said Dr. Darryl Sleep, Senior Vice President of Global Medicine and Chief Medical Officer at Amgen. “Amgen supports the ‘Break the Fracture’ initiative, dedicated to promoting proactive care approaches that help patients predict and prevent fracture events that severely impact quality of life.”
Cyrus Cooper, President of the International Osteoporosis Foundation (IOF) and Professor of Musculoskeletal Science at the University of Oxford, stated: “We are facing a substantial disease burden. As the global aging population continues to grow steadily, addressing osteoporosis and its associated fracture events has never been more critical for individual health.”
Dr. Philippe Halbout, CEO of the IOF, stated, “Implementing coordinated post-fracture care is the most effective[8] and efficient intervention to address the gap in secondary fracture prevention. I am pleased that Amgen, UCB, and the University of Oxford will support the ‘Break the Fracture’ initiative, dedicated to improving treatment outcomes for patients.”
Osteoporosis involves interdisciplinary treatment, highlighting the importance of coordinated care for patients. At the core of the “Break the Fracture” model is a care coordinator who helps identify, screen, diagnose, and appropriately treat patients with osteoporotic fractures to reduce their risk of future fractures. Post-fracture care coordination programs can improve diagnosis and treatment rates.[8],[9] This initiative aims to double the number of existing “Break the Fracture” programs to 390 by the end of 2022, with a focus on key regions including Asia-Pacific, Latin America, the Middle East, and Europe.
UCB’s Chief Medical Officer and Executive Vice President, Iris Loew-Friedrich (Iris Loew-FriedrichProfessor (PhD) stated, “The introduction of post-fracture care models is widely recognized as a positive milestone in the management of osteoporosis and osteoporotic fractures, and it remains a profound example of the beneficial outcomes achieved through care coordination among multiple disparate stakeholders. To address future challenges and alleviate the substantial burden on both healthcare systems and patients with osteoporosis, collaboration and cross-learning are essential. This global partnership supports UCB’s ambitions in connected health, enabling us to do more for patients and transform the lives of those with severe conditions.”
“Fracture Fix” Initiative welcomes existing fracture prevention alliances to collaborate at international, national, and regional levels to drive policy changes and prioritize fracture prevention. The initiative also includes the development and efficient implementation of various PFC projects, sharing best practices, creating a digital tool to record and disseminate the effectiveness of PFCs, and providing online and offline mentorship and learning opportunities for healthcare professionals.
Dr. Kassim Javaid, Associate Professor at the Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, stated, “The ‘Conquer Fracture’ initiative presents an excellent opportunity to leverage the academic skills and expertise of the University of Oxford to bring about truly beneficial improvements in the care of patients with osteoporosis.” Dr. Javaid, along with Dr. Rafael Pinedo-Villanueva, will lead the mentorship program and develop care pathways and benefit calculator software for the PFC project. They remarked, “We hope to transform the lives of millions through this project and look forward to collaborating with colleagues across China and internationally to realize this vision.”
For more information on the “Conquering Fractures” initiative, please visithttp://www.capturethefracture.org。