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Home Case Study: Prof. Li Junjie's Team at Huantai County People's Hospital Treats Hepatocellular Carcinoma Using Vispearl® Radiopaque Drug-Eluting Embolic Microspheres

Case Study: Prof. Li Junjie's Team at Huantai County People's Hospital Treats Hepatocellular Carcinoma Using Vispearl® Radiopaque Drug-Eluting Embolic Microspheres

May 27, 2026 08:59 CST Updated 08:59
H&H Healthcare

R&D and Producer of Interventional Medical Devices for Heart Disease



Introduction

The latest 《Guidelines for the Diagnosis and Treatment of Primary Liver Cancer (2024 Edition)》 recommend transarterial chemoembolization (TACE) as the first-line treatment for patients with CNLC stage IIa, IIIa, and partial stage IIIb. Similarly, international BCLC staging guidelines also recommend TACE as the first-line treatment for patients with BCLC stage B.

HuiHe Healthcare Radiopaque Drug-Eluting Microspheres Vispreal®The unique 40–90 μm small particle size meets diverse clinical needs. The radiopacity of Vispearl not only enables intraoperative tracking of the drug-eluting microspheres, but also facilitates immediate post-procedural evaluation of embolization efficacy and precise localization of tumor lesions throughout the follow-up period, better aligning with the concept of precision TACE.

In this issue, we will share a case report on the application of Vispearl by Professor Li Junjie's team at Huantai County People's Hospital®Radiopaque Drug-Eluting Embolic Microspheres for the Treatment of Liver Cancer: A Case Report.


Professor Li Junjie's Team
Huantai County People's Hospital




Patient Case Details



Basic Information: 46-year-old maleSex

History of Present Illness:Admitted for right upper quadrant abdominal pain lasting over 10 days.

Past Medical History:Chronic Hepatitis B

Laboratory Tests:HBV-DNA<1.00E+02  IU/ml ， AFP  >1000 IU/ml，Alanine aminotransferase 23 U/L, Total bilirubin 9 μmol/L

Imaging Examination:Preoperative contrast-enhanced CT shows multiple intrahepatic space-occupying lesions.

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Imaging shows: multiple intrahepatic lesions.



Surgical Plan:

Following MDT consultation, a liver biopsy was performed to confirm the pathological diagnosis, followed by transarterial chemoembolization (TACE) for further treatment to control tumor progression.




Surgical Procedure



`Percutaneous Right Femoral Artery``Puncture`，selective angiography of the celiac artery and superior mesenteric artery demonstrated: an irregular vascular mass and tumor staining were observed in the right hepatic lobe, measuring approximately 6.0 × 7.0 cm, and an irregular vascular mass and tumor staining were observed in the left hepatic lobe, measuring approximately 3.0 × 3.0 cm。

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Using a microcatheter and microwire, superselective catheterization was performed in the tumor-feeding arteries of the right and left hepatic arteries, respectively. Subsequently, 6 mL of iodized oil, 4 mg of raltitrexed combined with 1 g of Vispearl radiopaque drug-eluting microspheres (300–500 μm), and dozens of gelatin sponge particles were slowly injected into each artery.

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Repeat angiography after embolization demonstrated the disappearance of tumor blush.




Postoperative Follow-up



Imaging at 1.5 months postoperatively showed no significant tumor activity, and the therapeutic response was evaluated as CR according to mRECIST criteria.

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CT scan shows: no obvious tumor viability


Expert Profile




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Li Junjie | Professor

Chief Physician

Director, Department of Interventional Vascular Surgery, Huantai County People's Hospital


Committee Member, Peripheral Vascular Intervention Physicians Branch, Shandong Medical Doctor Association

Committee Member, Branch of Comprehensive Interventional Physicians, Shandong Medical Doctor Association

Member, Interventional Radiology Professional Committee, Shandong Medical Doctor Association

Member of the Committee on Interventional Diagnosis and Treatment of Digestive Diseases, Shandong Medical Association

Committee Member, Vascular Access Branch, Shandong Provincial Association of Integrative Medicine

Member of the Peripheral Vascular Intervention Professional Committee, Zibo Society of Integrated Traditional Chinese and Western Medicine

Committee Member, Interventional Radiology Branch, Zibo Medical Association

Committee Member, Minimally Invasive Tumor Therapy Branch, Zibo Medical Association

Committee Member of the Vascular Surgery Branch, Zibo Medical Association




Vispearl®Yingzhu®Radiopaque Drug-Eluting Embolic Microspheres

















































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