AI Drug Developer for Gut Microbiota

The article is sourced fromXbiome

Xbiome, with its leading AI microbiome research and industrial transformation platform, provided scientific research solutions and technical support for Mead Johnson Nutrition (China) Co., Ltd.'s study on "Changes in Gut Microbiota Before and After Adult Intervention with the Daily Joy Formula." The research findings were officially unveiled at the first Mead Johnson Nutrition and Health Innovation Research Institute High-Level Forum. Dr. Yan Tan, co-founder and CEO of Xbiome, along with key members of the research team, were invited to attend the forum.
Dr. Sa Xu, Chief Scientist and Innovation Officer of Mead Johnson Nutrition (China) Co., Ltd.Introduction: The subjects of this study were individuals experiencing bloating, reduced bowel movements, no severe diseases, and no history of abdominal surgery. The aim was to reveal changes in the gut microbiota before and after intervention. Using Xbiome's human gut microbiome research platform, researchers conducted sensory questionnaires and baseline stool sample tests on the aforementioned population, followed by a 21-day microbiome intervention. After the intervention, indicators such as microbial diversity, characteristic bacteria, SCFA, fecal bile acids, and calprotectin were measured in the participants.

Figure: Dr. Xu Sa giving a speech
The results showed that among the 45-55 age group, 75% of the participants experienced an increase in microbiota diversity during the intervention. Among the test population aged 45-65, there was a significant increasing trend in beneficial bacteria and immune-related bacterial genera. In all age groups of subjects tested, 60% showed a decrease in harmful bacteria.
The above results have preliminarily demonstrated that the Daily Joy formula has significant effects on increasing microbiota diversity, boosting beneficial bacteria, and inhibiting harmful bacteria in middle-aged and elderly populations. At the high-level forum, Xbiome and Mead Johnson Nutrition (China) Co., Ltd. jointly released the Mead Johnson Precision Nutrition Health Management Solution.

Figure: Group photo of the main members of both research teams
It is reported that in June 2023, Mead Johnson Nutrition (China) Co., Ltd. and Xbiome, a leading enterprise in microbiome research and development, signed a strategic cooperation framework agreement. The two parties will carry out in-depth cooperation in three major areas: AI + Microbiome Innovation Platform, Precision Nutrition Health Management Solutions, and Functional Probiotic Nutritional Product Pipelines. This is the first significant research achievement released since the beginning of their collaboration.
The human microbiome is a popular frontier field at present; cutting-edge scientific exploration has already discovered that the influence of the human microbiome spans the entire life cycle and is correlated with immunity, brain development, bone health, emotional well-being, and metabolic/chronic disease management.
Dr. Tan Yan, Founder and CEO of XbiomeXbiome has built an AI microbiome R&D and industrial transformation platform, dedicated to solving human health and disease problems by exploring microbial functions, becoming the preferred partner in the precision nutrition and health industry. It is hoped that the cooperation between the two parties will promote precision nutrition innovation and elevate precision nutrition to a scientific and evidence-based new level.

Figure: Dr. Tan Yan giving a speech
It is reported that the 2023 Asian Nutrition Conference, with the theme "Sustainable Nutrition for the Future," was guided by the International Union of Nutritional Sciences and hosted by the Chinese Nutrition Society and the Federation of Asian Nutrition Societies. The conference consists of eight main sessions, more than a hundred sub-forums, four special press conferences, and over 2,000 poster presentations; bringing together top experts and scholars in the field to share in this academic feast.

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