Allergan Aesthetics Announces Successful Development of BOTOX® for Platysma Prominence Indication
AbbVie
Innovative Drug Developer
On September 18, 2023, Allergan Aesthetics, a division of AbbVie Inc., announced the release of Botulinum Toxin Type A.Botox®New Indication Successfully Developed, it can be a potential treatment option for "moderate to severe platysma prominence." It is reported that the platysma in Westerners usually splits at the midline, presenting a cord-like appearance when contracted, forming a "turkey neck"; whereas in East Asians, the platysma tends to fuse at the midline. Therefore, "turkey neck" is relatively rare, and the condition more commonly manifests as hypertrophy of the submandibular tissue, loss of the mandibular contour due to loose skin, as well as horizontal neck lines and platysmal bands.
Allergan Aesthetics, as a company under AbbVie, is dedicated to the research, development, production, and sales of a series of advanced aesthetic brands and products, with its medical aesthetics business segment mainly coveringBotulinum toxin, hyaluronic acid fillers, breast beautification products, body shaping, and functional skincare productsand other fields. The predecessor of Aesthetics by Allergan was Allergan,In 2009, Allergan officially entered the Chinese market. On May 8, 2020, AbbVie Inc. completed the acquisition of Allergan for $64.084 billion and officially renamed it.Allergan Aesthetics。The medical beauty products of Allergan Aesthetics that have been launched in China includeBotox®BOTOX Botulinum Toxin, Juvederm® Hyaluronic Acid (6 fillers + 2 hydrating types), Natrelle® Breast Implants, McGhan® Breast Implants, CoolSculpting® Fat Freezing Device, and RESONIC® Pulse Device. In addition, in the field of botulinum toxin,As of now, the four botulinum toxin products that have been approved for marketing in China areBotox by Allergan, USABotox, Hengli by Lanzhou Bio, Dysport by French Ipsen, and Letybo by Korean Hugel;Meanwhile, five products under research are in the clinical stage., respectivelySouth Korea's Daewoong, Germany's Merz, South Korea's Huons (Aimeike), the United States' Revance (Fuxing Pharmaceutical), and domestically produced in ChinaMingmed Biologics
[Product Name]】Botulinum Toxin Type A
【Registration Certificate Number】S20070023
【Specification Model】100U/vial
[Product Features]
White powder (a clear, colorless to slightly yellowish liquid free of impurities after dilution with injectable saline)
【Product Positioning】
1.Treatment of blepharospasm, hemifacial spasm, and related focal dystonias in patients over 12 years old.
2. Improvement of moderate to severe glabellar lines caused by the activity of the corrugator and/or procerus muscles in adults 65 years of age and younger, as well as moderate to severe lateral canthal lines (crow's feet) in adults.
[Product Name]】
1. Cross-linked Sodium Hyaluronate Gel for Injection
2. Contains LidocaineCross-linked Sodium Hyaluronate for InjectionCoagulationGel
【Registration Certificate Number】
1. Elegant®: Registered Medical Device in China20153131709
2. Ultivo®: Registration No. 20153131708 (Imported Medical Device, China)
3.Volux®: China Medical Device Registration No. 20213130485
4. Juvederm Voluma® (with Lidocaine): Medical Device Registration in China20193130410
5. Tiyan®（Containing Ephedra）: National Medical Device Registration Import 20203130165
6. QualiFace® (with ephedrine): Medical Device Registration in China20213130109
【Specification Model】
1. U Series:Elegance®, Ultimate®
2. V Series:Volux®, Juvederm Vycross®, QualityYan®
[Product Features]
1. U Series: Utilizes Hylacross cross-linking technology
2. V Series: Utilizes Vycross cross-linking technology (with lidocaine)
【Product Positioning】
1. Elegance®：The core function is "smoothing wrinkles," targetingModerate to severe wrinkles such as nasolabial folds, marionette lines, crow's feet, and nasal dorsal lines, with an effective duration of up to 12 months.
2. Ultima®: The core function is "filling grooves".NeedleCorrectFilling and shaping of the temples, jaw, and other areas can last up to 12 months.
3. Volux®: The core function is "bone support".NeedleCorrectFacial volume reshaping and contour detail improvement for areas such as the apple muscle, cheeks, cheekbones, and chin, with an effective duration of up to 24 months.
4. Tiyan®: The core function is "dynamic filling",NeedleCorrectModification of areas such as nasolabial folds and perioral regions, with an effective duration of up to 18 months.
5. Zhiyan®: The core function is "lip injection",NeedleCorrectCorrect lip asymmetry, contour deformities, and volume deficiencies for up to 12 months.
[Product Name]】Cross-linked Sodium Hyaluronate Gel for Injection
【Specification Model】White Box Hydrate (1*1ml)/Box),Purple Box Volite（2*1ml/Box)
[Product Features]
1.White Box Hydrate: HA+Mannitol
2.Purple Box Volite: Cross-linked HA+Lysine Proline+Lidocaine
【Product Positioning】
1. White Box Hydrat: Hydration, Brightening, Antioxidant. Applicable to facial, neck, shoulder, and hand skin.
2. Purple Box Volite: Ultra-long-lasting Hydration Enhancement，Scope of ApplicationFace, neck, calves, hands.
[Product Name]】Silicone Gel-Filled BreastImplant
【Registration Certificate Number】CN Med Dev Reg 20163463328
[Specifications and Models] Standard type (35 models) and custom new type (355 models)
[Product Features]
1.AdoptBIOCELL Micro-Pore Foaming Technology
2.360-degree Seamless Integral Anti-seepage Barrier TM Technology
3. No massage required after surgery
【Product Positioning】
1. Used in plastic surgery for breast augmentation and breast reconstruction.
2.Suitable for thin but chest-enhanced beauty seekers。
[Product Name]】Single-lumen Silicone Gel Breast Implant
【Registration Certificate Number】China Medical Device Registration No. 2015346421
【Specification and Model】Round and Teardrop Shapes
[Product Features]
1. Micro-porous Surface Technology
2. The Enhancement of Seven-Layer Surface and Isolation Layer Technology
3. Strong Memory Shaping
【Product Positioning】
1. For breast augmentation and reconstruction.
2.Suitable for beauty seekers with flat chests.
[Product Name]】Cryolipolysis Device
[Registration Certificate Number]CN Medical Device Registration No. 20163582363
【Specification Model】CoolSculpting®Cryolipolysis Device
[Product Features]Non-invasiveSexCooling Instrument
【Product Positioning】
Suitable for reducing the fat layer in the abdomen and side waist areas where the fat thickness is greater than 1 cm and can meet the requirement of negative pressure suction.
[ProductBackground
In May 2021, Allergan Aesthetics successfully completed the acquisition of Soliton for approximately $550 million, enhancing Allergan Aesthetics' non-invasive body contouring treatment portfolio, which currently includes the approved medical device product Resonic for the treatment of cellulite appearance.
[Product Type]Resonic®Rapid Acoustic Pulse Device
[Product Features]Non-invasive treatments to improve the appearance of cellulite
【Product Positioning】
1.Long-term improvement in the appearance of orange peel tissue，The improvement cycle lasts up to 1 year.
2.Can be used with laser to remove tattoos.
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