Thermo Fisher to Showcase First User Data of Next-Gen High-Resolution Mass Spectrometer Orbitrap Astral Offline

　　【Pharmaceutical Network Enterprise News】Protein is a very important macromolecular organic compound in living organisms, closely related to human health. Proteins are highly complex and exhibit different spatiotemporal expression specificities across various levels such as species, tissues, and cells; during these changes, the same protein may take on different forms and display a wide variety of functions; these changes may occur in different cells, different cellular components, or even different protein complexes. Detecting the types and quantities of proteins in living organisms is of great significance for exploring the mysteries of life activities. Proteomics, as a technical approach that analyzes proteins in detail from an omics perspective, has also become an important means of studying protein function.
 

On September 25, 2023, the 12th China Proteomics Conference grandly opened in Chengdu. This conference will showcase major breakthroughs, cutting-edge achievements, new instrument and equipment exhibitions, and analytical technologies in the global proteomics field in recent years, promoting high-quality development in the industry. Among them, Thermo Fisher Scientific will present its latest generation of high-resolution...Mass SpectrometerThe first user data of Orbitrap Astral debuts offline, highly anticipated by the market.
 

The author learned from Thermo Fisher Scientific China Chromatography and Mass Spectrometry that at the ASMS conference held on June 4, 2023, Thermo Fisher Scientific announced the launch of the Orbitrap Astral mass spectrometer, which is based on a completely new mass analyzer. This instrument brings more possibilities to life science mass spectrometry applications and helps explore the vast universe of the living world.
 

Orbitrap features ultra-high resolution, mass accuracy, and dynamic range. The new Orbitrap Astral mass spectrometer will demonstrate its outstanding performance in multiple dimensions, including detection throughput, proteome coverage depth, sensitivity, and precise quantification. Compared with the older generation of Orbitrap instruments, the Orbitrap Astral can achieve lower sample loading, faster data acquisition methods, more compound identifications, and more accurate compound quantification results, completing precise identification and accurate quantification simultaneously.
 

Overall, the Orbitrap Astra meets the requirements of being "fast, stable, accurate, and powerful." The aspect of "stability" is reflected in the consistency of large-cohort data, "accuracy" is demonstrated in mass precision and the reliability of quantitative results, and "powerful" refers to the relentless performance of the Astra instrument. With the launch of this product, it will help advance the field of proteomics.
 

Currently, proteomics has entered a stage of high throughput, large-scale, and systematization, with a vast market size. Data shows that the global proteomics technical service market size grew from $1.7 billion in 2016 to $3 billion in 2020, with an annual compound growth rate of 14.7%, and it is expected to reach $6.8 billion by 2025. The development of proteomics in China started relatively late and is still in the early stages of the industry. The market size increased from 120 million RMB in 2016 to 580 million RMB in 2020, with an annual compound growth rate as high as 49.1%, and it is expected to reach 2.26 billion RMB by 2025.
 

Public information shows that Thermo Fisher Scientific is a leading company in the global scientific services field, committed to helping customers make the world healthier, cleaner, and safer. In the field of proteomics, Thermo Fisher has a comprehensive layout. Its subsidiary, Thermo Fisher Scientific B.V., provides a variety of proteomics solutions, including but not limited to: protein identification, protein modification and differential display, protein interaction studies, and protein expression profiling. In addition, Thermo Fisher also offers a range of proteomics reagents, instruments, software, and services.