|Edited by the Content Team of Zhong Peptide BiochemicalSeptember 25, 2023Day,Novartis Announces Lutathera’s Phase III NETTER-2 Trial Meets Primary Endpoint

Neuroendocrine tumors (NET) are a type of cancer that originates from neuroendocrine cells throughout the body and are generally considered to be slow-growing malignancies. HoweverSome NETs progress rapidly with poor prognosis, and in many cases, they are not diagnosed until the patient's condition has advanced to a late stage. Although NET is a rare disease, its incidence has increased by more than 500% in the past 30 years, creating an urgent need for more treatment options for newly diagnosed patients with inoperable or advanced stages.
NETTER-2 is the second Phase III trial of Lutathera, bringing clinically meaningful results to patients. Lutathera was approved by the FDA for marketing in 2018, primarily based on the pivotal NETTER-1 trial.
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1.Novartis radioligand therapy Lutathera® demonstrated statistically significant and clinically meaningful progression-free survival in first line advanced gastroenteropancreatic neuroendocrine tumors (GEP-NETs) | Novartis