Drug Development and Manufacturing

The 65th American Society of Hematology (ASH) Annual Meeting will be held both in-person and online from December 9 to 12, 2023. Clinical and real-world research findings on Novartis' therapeutic drugs in the field of hematological disorders will be presented at this conference. Let’s take a sneak peek at the highlights.
Novartis Hematology-Related Research Achievements
CML, MPN, GvHD, ITP, SAA, PNH and other fields
Total 82 Reports
Exploration of Nilotinib in the Treatment of CML for Achieving TFROral Report 446
Final Analysis of the ASCEMBL Study Results, Patient Baseline Mutations, and Impact AnalysisOral Report 449
ASCEND: A 48-Week Analysis of the Efficacy and Safety of STAMP Inhibitors as First-Line Treatment for CML-CPOral Report 865
X2101: Final Results Analysis of STAMP Inhibitor Monotherapy and Combination TherapyOral Report 450, 868
Real-world Experience with STAMP InhibitorsPoster 4541, 1809, 1803
AIM4CML: Exploration of Different Doses and Frequencies of STAMP Inhibitor MonotherapyPoster 3172
Development and Validation of Deep Learning Models —— Human-Machine Collaboration, Assisting in MPN Subtype DiagnosisOral Report 123
From raising scientific questions to exploring clinical translation
Model validation initiated by Jiangsu Provincial People's Hospital with multi-center participation
JUMP Study: Analysis of Ruxolitinib Treatment in 2233 Patients with MFPoster 5174
REVEAL Study: Assessment of Risk Factors for Disease Progression in PV PatientsOral Report 385
Germany GSG-MPN PV StudyOral Report 619
RESPONSE/RESPONSE2 Meta-AnalysisPoster 4553
REACH Series Study Data Update: REACH3 – Final Analysis Results at 3 YearsOral Report 654
Other Research Explorations:Multicenter Phase II StudyOral Report 653, 775
Eltrombopag for the Treatment of ITP:
Update on Phase III Study of Eltrombopag in Newly Diagnosed Pediatric ITP PatientsPoster 1223
IWISh 2.0 Results: Unmet Needs in ITP TreatmentPoster 1212
APPLY Study 48-Week Final AnalysisOral Report 571
APPLY & APPOINT Study on Patient-Reported Outcomes AnalysisOral Report 487
Multiple Research Posters and Abstracts
APPLY & APPOINT Hematological Response4084
APPLY & APPOINT BTH Analysis1338
Single-Dose PK and PD Study2723 4096
BAFF-R Monoclonal Antibody
Unique Dual Mechanism of Action:
NK Cell-Mediated ADCC
Blocking B-cell differentiation, proliferation, and survival signals
Shows great potential in ITP, wAIHA, CLL, and NHL.

Please stay tuned for the series of academic activities by Novartis Medical Department after the ASH meeting.
Data Interpretation in Hematological Diseases Field: December 12th - 20th
ASH Post-Conference Series 2024 January - March


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