Phenomic AI Secures Over $500M Strategic Collaboration with Boehringer Ingelheim to Advance Novel Targets for Stroma-Rich Cancers

▎Edited by the WuXi AppTec content team

Phenomic AI Announces Strategic Collaboration and Licensing Agreement with Boehringer Ingelheim to Discover Key Targets in Stroma-Rich Cancers. The collaboration will leverage Phenomic’s expertise in target identification and stromal biology using its scTx single-cell transcriptomics platform. This partnership aims to bolster Boehringer Ingelheim’s efforts to develop potential “first-in-class” drugs, transforming cancer treatment.

Cancers Rich in Stroma (Such as Colorectal and Pancreatic Cancer) Are Difficult to Treat Partially Due to the Presence of Tumor Stroma. This Complex Tissue Not Only Protects Cancer Cells from Existing Therapies but Also Promotes Cancer Growth and Metastasis. Phenomic's Innovative Platform Aims to Break Through the Tumor Stroma Barrier by Identifying New Targets, Significantly Extending Patient Survival.

Phenomic's unique scTx platform integrates a vast human tissue single-cell RNA dataset along with a series of analysis and validation tools. The platform utilizes advanced artificial intelligence and machine learning algorithms to analyze diverse databases, including imaging, RNA sequencing, and spatial transcriptomics data, to decode the complexity of individual cells within complex multicellular systems.Phenomic's unique stromal models and experimental capabilities enable it to identify new therapeutic targets through a cyclical process of digital screening and experimental validation.

Under this agreement, Boehringer Ingelheim has the right to develop targets discovered and validated by Phenomic AI, which could serve as the basis for new cancer therapies. Boehringer Ingelheim will also be responsible for all non-clinical and clinical development, as well as the commercialization of related cancer treatments. Phenomic AI will receive approximately $9 million in upfront and near-term payments, including research funding and collaboration milestones. Additionally, Phenomic AI is eligible to receive over $500 million in clinical, regulatory, and commercial milestone payments.

[1] Phenomic Enters Strategic Collaboration with Boehringer Ingelheim to Discover Novel Targets for Stroma-Rich Cancer Therapies. Retrieved November 29, 2023, from https://www.businesswire.com/news/home/20231129546391/en/Phenomic-Enters-Strategic-Collaboration-with-Boehringer-Ingelheim-to-Discover-Novel-Targets-for-Stroma-Rich-Cancer-Therapies

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