Home Hansoh Pharma (03692.HK) Enters into HS-20093 Licensing Agreement with GSK, Eligible for Up to $1.525 Billion in Milestone Payments

Hansoh Pharma (03692.HK) Enters into HS-20093 Licensing Agreement with GSK, Eligible for Up to $1.525 Billion in Milestone Payments

Dec 20, 2023 22:51 CST Updated 22:51
Hansoh Pharma

Pharmaceutical Research, Production, and Sales

Source: Guolon Holdings Limited

【Focus Today】

Hansoh Pharma(03692.HK): Entered into HS-20093 License Agreement with GSK, Milestone Payments Up to $1.525 Billion

Hansoh Pharma (03692.HK) announced that on December 20, 2023, its wholly-owned subsidiary, Shanghai Hansoh Biomedical Technology Co., Ltd. ("Licensor"), entered into a licensing agreement with GlaxoSmithKline Intellectual Property (No.4) Limited ("Licensee"). Under the agreement, the Licensee will be granted an exclusive global license (excluding China) to develop, manufacture, and commercialize HS-20093 ("the Product").

This product is a novel B7-H3-targeted antibody-drug conjugate (ADC), composed of a fully humanized B7-H3 monoclonal antibody covalently linked to a topoisomerase inhibitor (TOPOi) payload. It is currently undergoing multiple Phase I and Phase II clinical trials in China for the treatment of lung cancer, sarcoma, head and neck cancer, and other solid tumors.

According to the license agreement and its terms and conditions, the licensor will receive an upfront payment of $185 million and is eligible to receive milestone payments of up to $1.525 billion upon the achievement of related events for the product. After the product's commercialization, the licensee will also pay tiered royalties on global net sales outside of mainland China, Hong Kong, Macao, and Taiwan.

The licensee is a wholly-owned subsidiary of GSK plc (GSK), a global biopharmaceutical company headquartered in London, UK.

【Major Events】

Aidipalace(00286.HK) Opens Aide Gong Maternity Center in Guangzhou

China Qinfa(00866.HK) Reaches Loan Restructuring Proposal with Existing Creditors for Repayment of Original Debt

Fudan University, Shanghai(01385.HK): Shares of Fudan Microelectronics held by Shanghai Zhengben under judicial freeze/judicial marking account for 3.79% of the company's total shares.

【Earnings Report】

CEC INT'L HOLD(00759.HK) Interim Consolidated Revenue of HKD 7.51 Billion, Down 15.5% Year-on-Year

QPL INT'L (00243.HK) Interim Revenue of 133 Million HKD, Down 20.40% Year-on-Year

China Tobacco Hong Kong(06055.HK) Hansoh Pharma: Expected Annual Net Profit Increase of No Less Than 50%

【Operation Data】

China Mobile(00941.HK) Accumulated 5G Package Subscribers Reach 779 Million as of November

China Telecom(00728.HK) Releases November Operational Data: 5G Package Subscribers Reach 315 Million

Dexin China(02019.HK) Accumulated Contract Sales Amount for the First 11 Months Approximately RMB 21.14 Billion,

Shan High New Energy(01250.HK) Completed power generation of approximately 464,500 megawatt-hours in November, representing a year-on-year increase of approximately 37.0%.

【Pharmaceutical Innovation】

China Base Longevity Science(00767.HK) Enters into Strategic Cooperation Framework Agreement with Shenzhen Easipass Medical Supply Chain Management

Guichuang Tongqiao-B(02190.HK): ZENFLEX Peripheral Vascular Stent System Completes Patient Enrollment for Post-Market Clinical Trial in the EU Region

Ocumension Therapeutics-B(01477.HK): OT-703 Approved for Listing in Hong Kong

CanSino Biologics(06185.HK): Tetanus Adsorbed Vaccine Initiates Phase I Clinical Trial and Completes First Participant Enrollment

【Acquisition and Sale】

Prada(01913.HK) Plans to Acquire Property in New York, USA for $425 Million

Mountain High New Energy (01250.HK) Proposes to Acquire All Equity of Hengfeng County Fu Er Power, Providing Opportunities to Expand the Group's Business Portfolio in the Wind Power Industry

Dongfeng Group Corporation(00489.HK): Proposed Sale of 100% Equity in Xiangyang Industry & Trade for RMB 79.0344 Million

Brainstorm Technology(02203.HK) Further Sells a Total of 1,560 NVIDIA Shares

Dianchi Water Affairs(03768.HK) Sells 100% Equity of Hongyu Thermal Power

Tianli Holding Group(00117.HK) Subsidiary Enters into Third Acquisition Purchase Agreement with Donghai High Heat

【Equity Incentive】

Farma Holding(01521.HK) Grants 26,285,000 Share Options

Straw Bear Entertainment(02125.HK) Granted a Total of 464,000 Restricted Share Units

Shizishan Group(01127.HK) Granted 400,000 Reward Shares

【Increase/Decrease in Holdings】

Kintor Pharmaceuticals-B(09939.HK) Chairman of the Board, Executive Director and CEO Youzhi Tong Increased His Stake by 500,000 Shares

【Repurchase and Cancellation】

Tencent Holdings(00700.HK) Spent HKD 403 Million Repurchasing 1.28 Million Shares on December 20

AIA Insurance(01299.HK) Hansoh Pharma Spent HKD 134 Million Repurchasing 1.994 Million Shares on December 20

Li Ning(02331.HK) Hansoh Pharma Spent HKD 107 Million Repurchasing 5.537 Million Shares on December 20

HSBC Holdings(00005.HK) Repurchased 1.374 million shares at a cost of HK$82.8478 million on December 19

WuXi Biologics(02269.HK) Hansoh Pharma Spent HKD 38.608 Million Repurchasing 1.34 Million Shares on December 20

Sunshine Paper Industry(02002.HK) Hansoh Pharma Spent HKD 36.5428 Million Repurchasing 13.302 Million Shares on December 20

Haier Smart Home(06690.HK) Hansoh Pharma Spent 36.51 Million Yuan to Repurchase 1.8 Million A-shares on December 20

Swire Pacific A(00019.HK) Hansoh Pharma Spent HKD 18.952 Million to Repurchase 304,500 Shares on December 20

COSCO Shipping Holdings(01919.HK) Hansoh Pharma Spent HKD 18.9328 Million to Repurchase 2.49 Million Shares on December 20

ESR(01821.HK) Hansoh Pharma Spent HKD 15.71 Million to Repurchase 1.53 Million Shares on December 20

Yum China(09987.HK) Hansoh Pharma Spent $2 Million to Repurchase 48,700 Shares on December 19

BOSS Zhipin-W(02076.HK) Spent $1.998 Million to Repurchase 250,000 Shares on December 19

Jinke Service(09666.HK) Hansoh Pharma Spent HKD 9.8711 Million Repurchasing 1 Million Shares on December 20

Zhongyu Energy(03633.HK) Hansoh Pharma Spent HKD 5.5102 Million Repurchasing 1 Million Shares on December 20

Conch Cement(00914.HK) Hansoh Pharma Spent 5.37 Million Yuan to Repurchase 250,000 A-shares on December 20

Everything Cloud(02602.HK) Spent HKD 4.899 Million to Repurchase 200,000 Shares on December 20

Concord New Energy(00182.HK) Repurchased 6.4 million shares at a cost of HK$4.224 million on December 20

VESYNC(02148.HK) Hansoh Pharma Spent HKD 3.81 Million to Repurchase 755,000 Shares on December 20

SF同城(09699.HK) Hansoh Pharma Spent HKD 2.905 Million Repurchasing 289,200 Shares on December 20

Shou Cheng Holdings(00697.HK) Hansoh Pharma Spent HKD 2.8319 Million to Repurchase 1.978 Million Shares on December 20

Anling International(01410.HK) Hansoh Pharma Spent HKD 2.8457 Million to Repurchase 7.32 Million Shares on December 20

Longyuan Power(00916.HK) Hansoh Pharma Spent HKD 2.63 Million Repurchasing 451,000 Shares on December 20

Skyworth Group(00751.HK) Hansoh Pharma Spent HKD 2.627 Million to Repurchase 900,000 Shares on December 20

Harbour BioMed-B(02142.HK) Hansoh Pharma Spent HKD 2.215 Million Repurchasing 1.4 Million Shares on December 20

United Energy Group(00467.HK) Hansoh Pharma Cancels 249 Million Repurchased Shares on December 20

Medlive(02192.HK) 100,000 Repurchased Shares Cancelled on December 20