Neurodome Secures Tens of Millions in Pre-A Funding to Advance Non-Invasive Deep Brain Neuromodulation Platform

Recently, an innovative hard-tech enterprise focusing on non-invasive deep brain neuromodulation"Neurodome, Inc." (hereinafter referred to as "Neurodome Medical")Announced the completion of a Pre-A round of financing worth tens of millions of yuan.

This is another round of financing officially announced by Neurodome, Inc. in a short time after completing the angel round of funding from Frees Fund and Shunwei Capital earlier this year. This round of financing will be used for...Iterative Optimization of Temporal Interference (TI) Stimulation Technology,Accelerate Product Registration for Multiple Indications.

# Market Overview

The brain is known as the most complex object in the universe and is the source of thought, emotion, perception, behavior, learning, and memory.However, in the face of disease issues in this "final frontier" of natural science, what humanity can do remains very limited.

Currently, the number of patients with various brain diseases in China is nearly 130 million, indicating a huge demand for treatment. For instance, there are over 50 million patients with depression, more than 3 million with Parkinson's disease, and nearly 10 million with Alzheimer's disease. The burden caused by brain diseases accounts for 23% of the total disease burden.

In this regard, neuromodulation has become an effective clinical intervention due to its minimally invasive (non-invasive), highly targeted, highly reversible, and persistently adjustable characteristics. However, current deep brain neuromodulation solutions are mostly dominated by invasive craniotomy, while non-invasive interventions cannot balance depth and precision, failing to meet clinical expectations in terms of effectiveness.

TI technology achieves non-invasive deep brain electrical stimulation, combining the characteristics of spatial targeting and non-invasiveness. It can simultaneously meet clinical needs such as non-invasiveness, deep brain stimulation, high precision, and multi-targeting, effectively solving bottlenecks in existing technologies. It demonstrates excellent efficacy, safety, and compliance in the treatment of neuropsychiatric disorders such as depression, epilepsy, Alzheimer's disease, Parkinson’s disease, and insomnia. As a powerful scientific tool to advance brain science, it is expected to lead the development trend of brain science.

Professor Yiru Fang, Director of the Department of Psychology at Ruijin HospitalEvaluation: In terms of treatment interventions for mental disorders such as depression, existing antidepressant drugs have hit a bottleneck, with efficacy showing a "ceiling" effect. Therefore,Physical therapy based on neuromodulation technology is currently very clinically promising.

Professor Lu Yong, Director of the Brain Disease Center at Ruijin HospitalEvaluation:Development of TI TechnologyIt is targeted R&D aimed at unmet clinical needs, and demand-driven innovation can better meet the clinical market.

Dr. Wu Yiwen, Director of the Department of Neurology at Ruijin HospitalEvaluation: Brain stimulation technology has demonstrated good application effects in movement disorders.TI's Non-Invasive Stimulation TechnologyHas brought greater application prospects.

Dr. Chen-Cheng Zhang, Deputy Director of the Brain Center at Ruijin HospitalEvaluation: DBS has shown very significant effects, but according to a survey published by Tiantan Hospital, the current penetration rate of DBS in China is only 1.1%. Most patients still prefer non-invasive therapies, so non-invasive deep brain modulation represented by TI has greater clinical potential.

# Product Overview

Neurodome, Inc. has been deeply engaged in the field of neuromodulation, continuously refining TI technology, and has taken the lead in China to practically master and achieve precise non-invasive deep brain neuromodulation using TI technology in humans.

The latest launch by the companyThe 6th Generation Product: TIs EMO-1000/TIs CAPWith ultra-high precision stimulation control capabilities, it can accurately output various patterned stimulation signals, finely adjust parameters according to clinical needs, ensuring the accuracy, effectiveness, and repeatability of treatment protocols. It can perfectly achieve non-invasive, deep-brain, high-precision, multi-target central nervous system stimulation interventions and can be widely applied in the treatment of various neurological/psychiatric disorders.

The Sixth Generation Non-Invasive Deep Brain Neuromodulation Product TIs EMO-1000/TIs CAP

15px

Space after paragraph, select 8 (default is 24).

The color value of the red font is #ad2016.(Once selected, it will remain in your IE.)

WeChat articles should have more line breaks. You can leave a blank line between two sections.

Editor | Zhao Qing Reviewer | Yi He Typesetter | Miya