On January 4, in Turin, Italy, Resalis Therapeutics announced the completion of a €10 million (US$11 million) Series A financing round led by Sunstone Life Science Ventures, with participation from existing investors including Claris Ventures and angel investors. The proceeds will be used to initiate and complete the first Phase 1 clinical trial in humans and to support...RES-010Weight Loss Indication Reaches Phase 2 Readiness. RES-010 is an ncRNA-based compound designed to offer a disease-modifying approach for obesity, with the potential for more sustained weight loss and extended treatment durability when used in combination with approved therapeutic agents such as GLP-1 receptor agonists.
Chief of Resalis TherapeuticsExecutive Alessandro Toniolo stated:"The successful Series A financing is an important milestone for Resalis, as it will enable us to reach the clinic and achieve the next key inflection point with our lead candidate pipeline, RES-010. Through RES-010, we aim to provide a treatment that precisely reduces obese fat mass and has the potential to extend the durability of existing therapies. We value the trust and support of both new and current investors and look forward with great enthusiasm to the next phase of development."
Resalis Therapeutics has deep expertise in the field of ncRNA and RNA-targeted therapies for human health and metabolic disorders. The company’s lead candidate, RES-010, is an antisense oligonucleotide targeting miR-22, a central player in regulating lipid metabolism and energy expenditure. In multiple proof-of-concept studies in both large and small animal models, RES-010 has demonstrated the potential to deliver safe and durable therapeutic effects, either as a standalone treatment or in combination with approved drugs. Resalis Therapeutics plans to initiate a Phase 1 clinical study in the first half of 2024 to evaluate the safety and efficacy of RES-010. RES-010 is patent-protected in the United States, Japan, and China, with a patent application pending in the European Union.
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