Source: Vesber ；Editor: Bai XiaofeiReprint requirements: Can be reprinted 24 hours after the first publication, source must be credited.
Recently, the Ophthalmology Department of Harbin 242 Hospital successfully carried outThe First Case in Heilongjiang ProvinceThe Third Generation Foldable Artificial Vitreous Balloon（FCVB）Surgery! Professor Cui Hao's team implants a balloon for an ocular trauma patient.FCVB is a new type of eye-preserving technology., providing new treatment methods for patients with severe retinal detachment, ocular trauma, and silicone oil-dependent eyes, which is of great significance in saving the patients' eyeballs.
The Foldable Artificial Vitreous Balloon isGuangzhou Vesber Biotechnology Co., Ltd. (referred to as "Vesber")Independently DevelopedWorld's First Innovative Product。It has currently obtained the NMPA, EU CE certificate, and Australian TGA registration, and has been clinically applied in Asia, Europe, and Australia.
Mr. Liu lives in Acheng District, Harbin City. While splitting wood one time, he was accidentally injured in his right eye by flying wood chips. After the injury, he experienced eye pain, bleeding, and a decline in vision. His family immediately took him to Harbin 242 Hospital for treatment. After an examination, Director Cui Hao of the Ophthalmology Department found that the patient's right eye had light perception only, with a ruptured eyeball, a filled anterior chamber with accumulated blood, and a CT scan showing destruction of the posterior integrity of the eyeball along with a large amount of intraocular hemorrhage.The patient's intraocular tissues were severely damaged due to trauma. Dr. Cui Hao’s team urgently performed an exploration and suturing surgery for the rupture of the right eyeball. During the operation, a scleral wound approximately 20mm in length was found, with a significant amount of intraocular contents prolapsed.Due to the severe injury of the patient, traditional treatment can only involve enucleation and prosthetic eye implant surgery, which would result in the loss of part of the tissue and organ, causing significant psychological and physiological trauma to the patient. Therefore, preserving the eyeball has become Mr. Liu and his family's greatest hope for treatment.Considering Mr. Liu and his family's strong desire to preserve the eyeball, Director Cui Hao's team first conducted a comprehensive examination and assessment on him, and decided toImplantation of the Third-Generation Foldable Artificial Vitreous Body Balloon (FCVB)This new technology for eye preservation. However, as an innovative product application, the surgical team must submit a new technology application to the hospital leadership to carry out this service. The hospital leadership highly values this initiative and adheres to the hospital's founding principles of "respecting life, nurturing health, saving the dying and healing the wounded, and serving society."Urgently Complete the Approval Process, striving to treat patients with new technologies at the fastest speed.Dr. Liu Lei, Dr. Qu Jie, and other team members quickly completed the preoperative examinations and scoring for the patient, customized the model of the artificial vitreous balloon, and contacted the manufacturer for delivery.After full communication with Mr. Liu and his family, the team finally succeeded in performing the procedure for Mr. Liu.Right Eye Vitrectomy, Cataract Extraction, and Third-Generation Foldable Artificial Vitreous Balloon ImplantationThe entire surgery proceeded smoothly.The patient recovered well after the surgery, and the eyeball was preserved.The family highly praised Director Cui Hao and his team for their excellent diagnostic and treatment skills as well as their humane care services.Ruptured GlobeIs a disease that has a serious impact on the refractive media, retina and other tissues.，Its symptoms include ocular structural displacements such as lens dislocation, pupil deformation, ciliary body detachment, retinal defects, content prolapse, decreased intraocular pressure, and vitreous hemorrhage. Typically, the disease is associated with other symptoms like retinal injury, optic nerve damage, and skull base fractures.If treatment is not carried out in a timely manner, it will further lead to severe vision loss, blindness, or even enucleation.。Vitrectomy with Silicone Oil EndotamponadeUsually as the main means of treating such diseases,Can significantly improve the repositioning rate of complex retinal detachment and the cure rate of globe rupture.However, this surgical procedure also has certain defects.。Long-term retention of silicone oil in the eye and its contact with intraocular tissues can lead to intraocular toxicity and silicone oil emulsification. Postoperatively, patients usually require long-term intraocular silicone oil filling and regular replacement; otherwise, serious complications such as secondary cataracts, secondary glaucoma, corneal degeneration, and silicone oil emulsification may occur, potentially leading to blindness again. Meanwhile, due to the fact that the majority of fillers cannot effectively produce a tamponade effect on retinal breaks located inferiorly, this treatment method shows poor efficacy in complex cases of retinal detachment, such as traumatic retinal detachment, recurrent retinal detachment after multiple retinal reattachment surgeries in silicone oil-filled eyes, and silicone oil-dependent eyes.# The Third Generation Foldable Artificial Vitreous BalloonFoldable Capsular Vitreous Body (FCVB) is a new surgical method for treating severe eyeball rupture injuries., able toEffectively Overcome Silicone Oil Complications。The product consists of three parts: a balloon, a drainage tube, and a drainage valve. It is used for treating retinal detachment and severe eye trauma, offering excellent mechanical, optical, and biocompatibility properties.
▲ImageSource:Official Website
This product, through a design that simulates the natural vitreous cavity shape of the human eye, maintains the shape of the eyeball and intraocular pressure, provides long-term retinal tamponade, and avoids the risks of repeated silicone oil replacement and enucleation, as well as the occurrence of silicone oil-related complications. Physicians only need to...Implant into the vitreous cavity through a 4mm scleral incision and inject silicone oil from the drainage valve.This can restore the vitreous support for the patient's retina and eyeball, maintain the posterior chamber space, and slowly recover the function of the ciliary body to treat severe ocular trauma and silicone oil-dependent eyes.
In addition, this product avoids direct contact between the filler and the intraocular tissue, prevents silicone oil from emulsification, eliminates the need for repeated replacement, and effectively reduces complications caused by silicone oil. It can maintain the normal shape and appearance of the eyeball in patients with severe globe rupture injuries and silicone oil-dependent eyes. Moreover, silicone oil can be injected or extracted through the drainage valve to dynamically stabilize intraocular pressure.
It is reported that,The Foldable Artificial Vitreous Balloon is an Internationally Original Artificial Organ for Saving the EyeballSince its launch in 2017, the foldable artificial vitreous balloon implant surgery has been performed by more than 100 ophthalmologists across 24 provinces in China, covering over 100 hospitals, serving approximately 2,500 patients. This product was included in the 2018 National Medical Device Innovation Product Catalog by the Ministry of Science and Technology, and was listed by the National Medical Products Administration as part of the review of the 40th anniversary of China's reform and opening-up.A Typical Example of "Made in China" Evolving into "Created in China"。
Guangzhou Vesber Biotechnology Co., Ltd. was established in 2007 and is a company focused onOphthalmic Innovative Product R&D, Production, and SalesA national high-tech enterprise located in the core area of the Guangdong-Hong Kong-Macao Greater Bay Area — Nansha District, Guangdong Medical Valley Industrial Park — has received investments from state-owned enterprises such as Yueke Financial Group, Guangzhou Kaido Holdings Co., Ltd., ChiNext-listed company Oupukang Vision, Guangdong Xiangsanzhe Pharmaceutical Venture Capital Company, and Leishi Investment.CompanyRelying on the strong R&D platform of Zhongshan Ophthalmic Center, adhering to a rigorous, scientific, and responsible attitude, meticulously develop innovative ophthalmic products. The main products includeFoldable Artificial Vitreous Balloon (FCVB), Foldable Top Press Balloon (FCB), High Myopia Scleral Reinforcement System (HM), etc.。FCB is an innovative product for the minimally invasive treatment of rhegmatogenous retinal detachment. Clinical research was initiated in July 2019, with a total of 21 ophthalmic hospitals participating in the clinical study of this project. The product's market launch brings new hope to a large number of patients with rhegmatogenous retinal detachment.
HM, independently developed by Vesber, is used to delay the progression of myopia and treat conditions such as posterior scleral staphyloma and retinoschisis caused by high myopia. It has currently received ethical review approval from Beijing Tongren Hospital and is undergoing clinical trials in multiple hospitals.
Since its establishment, the company has successively received funding from a series of government funds, including the National 863 Project, the Twelfth Five-Year Support Plan, the SME Innovation Fund, the Guangdong Province Industry-University-Research Collaboration, and the Guangzhou Science and Technology Plan, holding 24 patents in the United States, Australia, China, and other countries.As of the date of this report, the company's financing history is as follows:
