Source: Eye Future；Editor: Bai XiaofeiReprint Requirements: Can be reprinted 24 hours after the first publication, source must be cited.
Recently,The World's FirstAstigmatism-Correcting Extended Range of Vision Intraocular Lens – Johnson & Johnson Vision TECNIS Symfony™ Toric IOLInZhuhai C-MER Dennis Lam Eye HospitalCompletedThe First Implantation in Guangdong ProvincePerformed by President Ding Jin, an expert from the headquarters of C-MER Eye Care Group.
The successful implementation of this surgery will further expand the options for functional intraocular lenses among cataract patients, and also marks a further breakthrough in the introduction of new technologies at Zhuhai C-MER Eye Hospital.TECNIS Symfony™ Toric IOL isThe World's FirstExtended Depth of Focus Toric Intraocular Lens, specifically designed for cataract patients with astigmatism. The product utilizes the patented "Echelette diffraction grating" technology,Provide full-range continuous vision without astigmatism。InOfficially received registration approval from the National Medical Products Administration in October 2023, entering the Chinese market.
▲Originated fromZhuhai C-MER Dennis Lam Eye Hospital
# Patient Details and Surgical PlanMr. Zhou (pseudonym), 54 years old, is aHigh myopia and astigmatism with mild cataractThe patient, who usually enjoys sports and needs to drive at night, has high requirements for full-range vision. Therefore, introduced by a friend, the patient came from Macao to Zhuhai C-MER Eye Hospital."My eye problems have already affected my life, and I don't want to continue wearing glasses after the surgery." Based on Mr. Zhou's vision needs, President Ding Jin conducted a detailed evaluation.The patient was fitted with the TECNIS Symfony™ Toric IOL, a toric intraocular lens designed for astigmatism correction and extended range of vision.This artificial crystal uniquely features innovative EDOF continuous vision technology, correcting astigmatism while providing high-quality continuous vision from near to far distances for patients with cataracts and presbyopia.Dean Ding Jin introduced: In cataract surgery, the selection of intraocular lenses is strictly evaluated by doctors from multiple aspects. After thorough and meticulous preoperative preparation, Dean Ding Jin...Successfully performed the much-anticipated first Symfony™ Toric Extended Range of Vision IOL implantation surgery in Guangdong Province using phacoemulsification for cataracts., the entire surgical procedure went very smoothly.▲President Ding Jin Performs Symfony™ Toric New Infinite™ Intraocular Lens Implantation SurgeryDuring the surgical implantation process, the implantation procedure for the TECNIS Symfony™ Toric IOL is no different from that of the TECNIS™ one-piece monofocal toric intraocular lens.But it requires higher astigmatism correction.. As an IOL for presbyopia and astigmatism correction,TECNIS Symfony™ Toric IOL Intraoperative Manipulation and Attention to Detail Ensure Postoperative Rotational Stability, the following should be noted during operation:① Continuous Circular Capsulorhexis (CCC), with a diameter of 5.0~5.5mm, the tear should cover the edge of the TECNIS Symfony™ Toric IOL optic portion to ensure good rotational stability;② Thorough Removal of Ophthalmic Viscoelastic Devices After Initial Intraocular Lens PositioningEspecially the viscoelastic agent located behind the intraocular lens, the residual viscoelastic agent may increase the rotation of the intraocular lens.③ The water should not be injected too quickly when the incision is closed., to prevent the properly positioned TECNIS Symfony™ Toric IOL from rotating again, inject an appropriate amount of fluid to achieve moderate intraocular pressure;④ Gently press the optical part of the lens after final positioning., with the help of the Tri-Fix 3-point fixation design generating backward force, the TECNIS Symfony™ Toric IOL is made to closely adhere to the posterior capsule of the lens, avoiding edge clamping by the anterior capsulorhexis opening.⑤ It is recommended that the patient lie flat for 2-3 hours with eyes closed to rest after the surgery, and avoid lying on the side of the surgical eye.# TECNIS Symfony™ Toric Intraocular Lens
▲Source: Company's official website
TECNIS Symfony™ Toric IOL isThe World's FirstExtended Depth of Focus Toric Intraocular Lens, specifically designed for cataract patients with astigmatism. The product features a patented "Echelette Diffraction Grating"Technology,Provide full-range continuous vision without dispersion; Patent "Achromatic Active Achromatism Technology"，Active correction of chromatic aberration，Provide High-Quality Contrast Sensitivity; and hasExcellent Stability, including long-term, refractive, and rotational stability.
▲Source: Company's official website
By combining the EDOF continuous vision crystal patent "Echelette Diffraction Grating"Technology andMultifocal LensThe technology, the crystal canAchieveFrom 33cm to far distance, providing high-quality continuous vision of 0.8 or above for cataract or presbyopia correction patients, enabling cataract patients with astigmatism to correct corneal astigmatism while achieving continuous, all-day, all-distance vision from far to near without blur.
It adopts innovative hydrophobic acrylic material, which canEffectively filter harmful ultraviolet light and reduce optical interference, ensuring nighttime driving safety while allowing beneficial blue light to improve visibility in low-light conditions.Visual quality, providing patients with better circadian rhythms, systemic health, mood, and sleep.
TECNIS Symfony™ Toric IOL has a certain tolerance for large Alpha angles and IOL decentration, with low dependency on pupil size, among mainstream presbyopia-correcting intraocular lenses.Can provide better low-light vision, offering patients superior visual quality, with a high rate of spectacle independence at far and intermediate distances.。Studies have shown that in the case of residual astigmatism as high as 1.0 D,Using TECNIS Symfony™ Toric IOL can still maintain 20/20 or better vision.。After implantation of the TECNIS Symfony™ Toric IOL, an average postoperative cylinder correction of 0.32 ± 0.34D can be achieved.In a prospective, open-label study lasting 6 months, cataract patients with preoperative astigmatism who received the TECNIS Symfony™ Toric IOL implantation (n=39) achieved an average postoperative cylindrical correction of 0.32 ± 0.34D.92% of patients had residual refractive astigmatism ≤0.5D after surgery, and 97% of patients had residual refractive astigmatism ≤1.0D after surgery.。
Compared with single-focus IOL, Toric IOL implantation can achieve less postoperative residual astigmatism and a higher rate of spectacle independence.However, postoperative attention should be paid to the risk of IOL rotation.Rotation of Toric IOL generally occurs within 1 week after surgery, and a rotation of more than 30° can completely eliminate the astigmatism correction effect. Therefore, more careful examination is needed in the early postoperative period after Toric IOL implantation.Generally, methods such as slit-lamp microscope examination after mydriasis, residual astigmatism detection, and wavefront aberration meter detection can be used to evaluate the clinical effects of the surgery and the stability of the IOL.。
TECNIS Symfony™ Toric IOL meets the ANSI Z80.30 rotational stability requirements for toric intraocular lenses set by the American National Standards Institute (ANSI).。A prospective, unmasked, randomized clinical trial evaluated the rotational stability of the TECNIS Symfony™ Toric IOL. The results showed,Among the listed time period/method combinations, all but one (89%)...The percentage of eyes with rotation ≤5 degrees is greater than 90%.。The proportion of eyes with rotation ≤5 degrees analyzed using image analysis from 1 day to 1 month and from 1 day to 3 months was statistically significant.(p values all < 0.05)
▲Rotational Summary Data Based on Slit Lamp Measurements or Image Analysis Systems
The Kappa angle refers to the angle between the visual axis (nodal axis) and the optical axis (pupil axis). In corneal refractive surgery, the ideal ablation center should completely overlap with the visual axis. With the advancement of cataract surgery techniques and continuous improvements in intraocular lenses, especially the application of multifocal intraocular lenses with refractive or diffractive optical centers,A large Kappa angle can lead to postoperative visual quality degradation and visual discomfort such as glare.。TECNIS Symfony™ IOL Has Better Tolerance for Kappa Angle。A prospective clinical study enrolled 152 eyes of 103 patients who successively underwent cataract surgery and were implanted with TECNIS Symfony™ IOL at Daqing Oilfield General Hospital from January 2019 to September 2019. Patients were divided into three groups based on the preoperative Kappa angle (r):Uncorrected visual acuity was examined preoperatively and at 7 days, 1 month, and 3 months postoperatively. Comprehensive optometry, higher-order aberrations, and defocus were assessed at 3 months postoperatively.The results showed,Compared with preoperative levels, the uncorrected visual acuity of patients in all three groups significantly improved postoperatively.（P<0.001）。In addition,TECNIS Symfony™ IOL has a wide range of diopters and good tolerance for refractive errors.。
A prospective, non-randomized, comparative, interventional study enrolled 44 patients (88 eyes) who underwent cataract surgery with bilateral implantation of either a continuous range of vision intraocular lens (TECNIS Symfony™ IOL) or a monofocal intraocular lens (TECNIS ZCB00). Visual acuity, refraction, defocus curve, contrast sensitivity, optical phenomena, spectacle independence, and patient satisfaction were evaluated at 4 months postoperatively.
The results showed,Most visual and refractive parameters showed no significant differences postoperatively between the two groups (all P≥0.27).The binocular uncorrected intermediate and near visual acuity in the continuous vision group was significantly better (P < 0.01).。
One of the reasons why patients choose TECNIS Symfony™ IOL after LASIK surgery is its good tolerance for refractive errors.Not only that, but compared to monofocal IOLs,TECNIS Symfony™ IOL Group Has Lower Dependence on Glasses for Intermediate and Near Vision。
▲Distribution of Spectacle Dependence Levels After Intraocular Lens Surgery
# About Johnson & Johnson
Johnson & Johnson (NYSE: JNJ) was founded in 1886 and is the world's most comprehensive healthcare enterprise with a wide range of business operations, coveringConsumer Goods, Pharmaceuticals, Medical DevicesThree major fields. Headquartered in New Brunswick, New Jersey, the United States, with more than 260 operating companies in over 60 countries and regions worldwide, and a global workforce of more than 140,000 employees.Johnson & Johnson Vision isJohnson & Johnson's division specializing in ophthalmic operations, with a rich product line, including: Johnson & Johnson Vision Care and Vision Business.The main business of Johnson & Johnson Vision is surgical operations and related consumables., covering related surgical operations such as cataract and laser refractive surgery, with products including the artificial crystalline lens brand TECNIS, etc.Johnson & Johnson Vision Care mainly focuses on the contact lens business., with brands Acuvue and cosmetic lenses brand Blink, which are leading brands in the industry. In 1988, it launched the world's first replacement contact lens, and subsequently introduced daily disposables and cosmetic lenses, driving the transformation of the vision correction products industry at that time.
